0818 - Epidemiology of CKD - EG

Question 1

Define CKD

Answer 1

CKD is defined with a >3 months of:

(1) A marker of kidney damage: albuminuria, urine sediment abnormalities, electrolyte abnormalities, structural or histological abnormalities
(2) Decreased GFR <60 ml/min/1.73m2.

Question 2

What are some of the epidemiological statistics on CKD?

Answer 2

Renal disease accounts for <1% of total disease burden (Aus), yet its management consumes 5.7% of the Australian Health Care budget.
In Australia, dialysis is required by about 0.1% of the population
o 35% due to diabetes
o 22% due to glomerulonephritis
o 14% due to hypertension

Question 3

What were some of the findings of the Asudiab study?

Answer 3

• 1 in 7 have evidence of kidney disease
• 1 in 50 have severe kidney disease (GFR <30ml/min – stages 4 or 5
• Major risk factors are hypertension and diabetes.
• CKD is more common in those over 65 years of age, and at this age more likely to have proteinurea, haematuria, and renal impairment (stage 3a most prevalent).
• Greatest prevalence in those with stage 3 CKD (10.9%)
• Low prevalence of people with ESRD (0.02%)

Question 4

What are the implications of DM and CKD?

Answer 4

50% of DM patients develop CKD in 30 years

Question 5

What are the implications of proteinuria and CKD?

Answer 5

presence of proteinuria is linked to increased stage and risk of CKD.