0815- immunopathologies- CG

Question 1

What is Immunopathology

Answer 1

Immunopathology = Defence evolved a number of strategies for dealing with different pathogenic threats, requiring accurate activation and termination.Immunopathology failure to regulate these responses normally

Question 2

Give examples of what could go wrong in the immune system to cause immunopathlogies

Answer 2

Problems arising from issues with:

soluble mediators (ie complements)

Antigen- binary response (self or not)

Cellular components- innate or acquired (unregulated)

Question 3

Compare qualitative and quantitative defects

Answer 3

quantitative defects- inappropriate magnitude leads to

Immune deficiency

Excessive immune response

qualitative defects- Inappropriate type of immune response for the

nature of pathogen

Nature of antigen- self vs foreign

Question 4

Describe Innate Immunopathologies: pathological activation of inflammation

Answer 4

Question 5

Describe Gel and coombe’s classification of Immunopathologies of the Specific Immune System

Answer 5