02 - sarcomas and mast cell tumors

Question 1

Question 2

(soft tissue sarcomas)

(biologic behavior)

1. usually invasive and infiltrative with poorly defined margins
2. metastasis depends on the grade of the tumor

Question 3

(soft tissue sarcomas)

(liposarcoma)

1. originate from adipocytes
2. rare
3. invasive and agressive?
4. how common is mets?

Answer 3

3. yes
4. rare

Question 4

(soft tissue sarcomas)

Question 5

(soft tissue sarcomas)

(fibrosarcoma)

1. common
2. invasive but slow grwoing
3. how common is mets?

Answer 5

3. rare

Question 6

(soft tissue sarcomas)

(hemangiosarcoma)

1. originates from what?
2. rapid growing and invasive?
3. usually in what organs?
4. how common is mets?
5. may cause collapse if what occurs?

Answer 6

1. endothelium of blood vessels
2. yes
3. spleen, heart, and skin
4. common
5. tumor ruptures with hemorrhage

Question 7

(soft tissue sarcomas)

(neurofibrosarcoma)

1. originates from what?
2. slow-growing but invasive, how common is mets?
3. commonly occurs where?

Answer 7

1. nerve sheaths
2. rare
3. brachial or lumbosacral plexus

Question 8

(soft tissue sarcomas)

1. what is the treatment of choice?

Question 9

(soft tissue sarcomas)

1. what is the treatment of choice?
2. when is radiation tx used?
3. chemo is best used when?

Answer 9

1. surgical excision (with wide margins)
2. when the tumor cannot be completely excised
3. after incomplete excision

Question 10

(mast cell tumors)

1. high risk breeds?

Answer 10

1. boxers, boston terriers, english bulldogs, english bull terriers, shar peis, labs, goldens

Question 11

(mast cells)

Question 12

(mast cells)

Question 13

(mast cells)

Question 14

(mast cells)

1. what is the treatment of choice?
2. give what before sx?

Answer 14

1. surgical excision with wide margins
2. anti-histamines

Question 15

(osteosarcoma)

1. what % of primary bone tumors in dogs are OSAs?
2. usually found where in bones?
3. more common in small or large dogs?
4. how aggressive in cats?
5. tx?
6. prog is poor if mets, long-term prog is poor

Answer 15

1. 85%
2. metaphysis
3. large dogs
4. less
5. tx with chemo

Question 16

(chondrosarcoma)

1. what % of primary bone tumors are these?
2. sx ^ survival, but long term survival still poor

Answer 16

1. 5-10%

Question 17

fibrosarcomas and hemangiosarcomas are the next most common bone tumors in dogs

Question 18

metastatic bone tumors usually go where?

Answer 18

diaphysis