01 - oncology principles

Question 1

(lymphoma)

(cause)

1. in cat or dog can retrovirus cause?

Answer 1

1. cat (FeLV and FIV)

no viral etio in dog

Question 2

(lymphoma)

1. stage 1 = ?

2

3

4

5

Answer 2

1. single lymph node
2. multiple LN in a regional area
3. generalized lymphadenopathy
4. liver or spleen involvement
5. bone marrow/blood/non-lymphoid organ involvement

substage a = w/o Cx, b = with

Question 3

(lymphoma)

1. which form is most common in dog?
2. Cx?

Answer 3

1. multicentric
2. enlarged LN

(wt loss, dec appetite, PU/PD)

Question 4

alimentary lymphoma has GI signs

Question 5

mediatstinal lymphoma causes what kinds of signs?

Answer 5

respiratory

Question 6

cutaneous lymphoma can be pruritic

Question 7

In dog are most b or t cell lymphomas?

T cell are associated with what?

Answer 7

b cell

hypercalcemia, and cranial mediastinal tumors

Question 8

most FeLV associated tumors in cats are b or t cell?

Answer 8

t-cell lymphomas

Question 9

Question 10

(lymphoma)

(dx)

1. palpate all LN
2. evaluate organ involvement - especially what two organs?
3. bone marrow involvement can cause hematologic abnormalities
4. opthalmic problems occur in what % of dogs?

Answer 10

2. liver or kidney
3. 33%

Question 11

(lymphoma)

(dx)

(lab eval)

1. what are usually seen in circulation?
2. hypercalcemia in what %?
3. most cats with mediastinal or multicentric lymphoma are FeLV positive

Answer 11

1. immature lymphocytes
2. 20%

Question 12

(lymphoma)

1. what kind of radiographs should be taken in any case of hypercalcemia of unknown origin?

Answer 12

1. thoracic

Question 13

histo of LN is recommended

with only cytology, neoplasia can be difficult to distinguish from benign lymphadenopathy

Question 14

Question 15

what is the CHOP combination?

Answer 15

cyclophosphamide

doxorubicin (hydroxydaunorubicin)

vincristine (oncovin)

prednisone

Question 16

what drug by itself achieves remission in what 70% of dogs?

Answer 16

doxorubicin

Question 17

prednisone by itself is cheap - but only get survival of about 2 months

Question 18

Question 19

which is worse - T or B cell lymphoma

Answer 19

T (t is for terrible!!!)

Question 20

(lymphoid leukemia)

(acute lymphoblastic leukemia)

1.

Question 21

(lymphoid leukemia)

(acute lymphoblastic leukemia)

(diagnosis)

1. documentation of what in bone marrow or blood?

Answer 21

1. abnormal lymphocytes

Question 22

(lymphoid leukemia)

(acute lymphoblastic leukemia)

1. how different from lymphoma?

Answer 22

Question 23

(lymphoid leukemia)

(acute lymphoblastic leukemia)

1. tx?
2. prog?

Answer 23

1. chop
2. prog

Question 24

Answer 24

Question 25