01 - oncology principles Flashcards

1
Q

(lymphoma)

(cause)

  1. in cat or dog can retrovirus cause?
A
  1. cat (FeLV and FIV)

no viral etio in dog

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2
Q

(lymphoma)

  1. stage 1 = ?

2

3

4

5

A
  1. single lymph node
  2. multiple LN in a regional area
  3. generalized lymphadenopathy
  4. liver or spleen involvement
  5. bone marrow/blood/non-lymphoid organ involvement

substage a = w/o Cx, b = with

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3
Q

(lymphoma)

  1. which form is most common in dog?
  2. Cx?
A
  1. multicentric
  2. enlarged LN

(wt loss, dec appetite, PU/PD)

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4
Q

alimentary lymphoma has GI signs

A
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5
Q

mediatstinal lymphoma causes what kinds of signs?

A

respiratory

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6
Q

cutaneous lymphoma can be pruritic

A
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7
Q

In dog are most b or t cell lymphomas?

T cell are associated with what?

A

b cell

hypercalcemia, and cranial mediastinal tumors

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8
Q

most FeLV associated tumors in cats are b or t cell?

A

t-cell lymphomas

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9
Q
A
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10
Q

(lymphoma)

(dx)

  1. palpate all LN
  2. evaluate organ involvement - especially what two organs?
  3. bone marrow involvement can cause hematologic abnormalities
  4. opthalmic problems occur in what % of dogs?
A
  1. liver or kidney
  2. 33%
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11
Q

(lymphoma)

(dx)

(lab eval)

  1. what are usually seen in circulation?
  2. hypercalcemia in what %?
  3. most cats with mediastinal or multicentric lymphoma are FeLV positive
A
  1. immature lymphocytes
  2. 20%
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12
Q

(lymphoma)

  1. what kind of radiographs should be taken in any case of hypercalcemia of unknown origin?
A
  1. thoracic
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13
Q

histo of LN is recommended

with only cytology, neoplasia can be difficult to distinguish from benign lymphadenopathy

A
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14
Q
A
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15
Q

what is the CHOP combination?

A

cyclophosphamide

doxorubicin (hydroxydaunorubicin)

vincristine (oncovin)

prednisone

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16
Q

what drug by itself achieves remission in what 70% of dogs?

A

doxorubicin

17
Q

prednisone by itself is cheap - but only get survival of about 2 months

A
18
Q
A
19
Q

which is worse - T or B cell lymphoma

A

T (t is for terrible!!!)

20
Q

(lymphoid leukemia)

(acute lymphoblastic leukemia)

1.

A
21
Q

(lymphoid leukemia)

(acute lymphoblastic leukemia)

(diagnosis)

  1. documentation of what in bone marrow or blood?
A
  1. abnormal lymphocytes
22
Q

(lymphoid leukemia)

(acute lymphoblastic leukemia)

  1. how different from lymphoma?
A
23
Q

(lymphoid leukemia)

(acute lymphoblastic leukemia)

  1. tx?
  2. prog?
A
  1. chop
  2. prog
24
Q
A
25
Q
A