01b: COPD Flashcards
Emphysema is pathologically characterized by (increase/decrease) in (X) and an abnormal (increase/decrease) in size of (Y).
Decrease;
X = total gas-exchanging airspaces
Increase;
Y = remaining airspaces
Which portion of respiratory airspaces are destroyed in emphysema?
Resp bronchioles and beyond (alv duct, alv sac, or alveolus)
T/F: Breath sounds are diminished in emphysema.
True - diaphragm doesn’t move with respiration
(X) is an alteration in structure/function of (R/L) (atrium/ventricle) caused by primary disorder of the respiratory symptom. This can occur in advanced emphysema.
X = cor pulmonale
RV
Dyspnea of extreme severity occurring with normal ADLs is typically seen at FEV1 less than:
750 mL
Emphysema patients usually die as a result of which diseases/complications?
- HF
- PE
- Infection
- Resp insufficiency
What’s a downside to utilization of inhaled corticosteroids in COPD patients?
Increased risk of pneumonia
T/F: If emphysema patient doesn’t exhibit improvement in flow rate after bronchodilator use in pulmonary lab, a bronchodilator should not be prescribed; patient may rely on it too heavily.
False - should be tried in those patients
Chronic bronchitis and (emphysema/bronchiectasis/asthma) patients always produce sputum.
Bronchiectasis
(Bronchitis/bronchiectasis) directly involves destruction of the gas exchanging structures in lung.
Neither! Destruction is of the airway wall components
List some etiologies of bronchiectasis.
- CF
- Kartagener’s syndrome (“immotile ciliary syndrome”)
- Post-infectious (rare)
- Allergic aspergillosis
T/F: Chronic bronchitis/bronchiectasis patients will have diminished breath sounds and hyper-aeration (like emphysema)
False - no hyper-aeration
Secondary erythrocytosis aka polycythemia is an (increase/decrease) in (X). It’s seen in (emphysema/bronchitis) and occurs in response to (Y).
Increase;
X = RBCs
Bronchitis/bronchiectasis
Y = Chronic hypoxia (leads to increased EPO production)
T/F: Diffusing capacity is usually within normal limits in chronic bronchitis/bronchiectasis patients.
True
Why might diuretics be important in medical therapy for (emphysema/bronchitic) patients?
Bronchitic;
Help mobilize fluid and improve cardiac performance
Normally, (X)% of forced vital capacity is exhaled in the first second.
X = over 70%
Hence: FEV1/FVC ratio should be over 70%