01. KFP Insights: Formats and Cases Flashcards
Characteristics of migraine?
- Recurrent attacks that last 4-72 hours
- Typically on sided, pulsating, moderate to severe intensity, aggravated by routine physical activity
Characteristics of migraine with aura?
Migraine
- Recurrent attacks that last 4-72 hours
- Typically on sided, pulsating, moderate to severe intensity, aggravated by routine physical activity
Aura:
- Reversible focal neurological symptoms that usually develop over 5-20 minutes and last for less than 60 minutes
- Symptoms can affect vision, sensors, speech and/or , motor function, brainstem and retina
Characteristics of tension type headache?
- Last from 30 minutes to seven days
- Usually bilateral, feels like pressure or tightness in their head
- Not associated with nausea
- May be associated with photophobia
Management of medication over-use headache?
- Commence NSAID e.g. naproxen
- Cease/gradually reduce offending medication
Options for prophylaxis in migraine?
- Candesartan
- Amitriptyline
- Verapamil SR
- Propranolol
- Pizotifen
Characteristics of pityriasis rosea?
- Self limiting inflamamtory skin condition
- Cause: viral infection (reactivation of human herpesvirus 6 or 7)
- Starts with a herald patch and then 2 weeks later, multiple scaly, oval, salmon-coloured macules appear
- Macules confined to the trunk and proximal limbs, Christmas tree appearance as it follows the skin tension lines
- Rx: no specific treatment is required as it is benign and not contagious
- DDx: guttate psoriasis, secondary syphilis
What exam findings would you search for when assessing for an alternative cause of frequent urination other than urge urinary incontinence?
- Appearance of frailty
- Problems with mobility, problems with transfers
- Cognitive impairment, cognitive function
- Presence of enlarged bladder
- Presence of pelvic mass
- Presence of Atrophic vulval or vaginal changes
- Presence of pelvic organ prolapse
- Loss of urine observed at the urethral meatus on coughing
- Presence of constipation, faecal impaction on digital rectal examination
- Presence of altered perineal sensation on digital rectal examination
- Presidents of altered anal tone
- Presence of perineal skin disease (e.g. Dermatitis, thrush)
- Presence of lower limb weakness
- Presence of upper motor neuron signs On lower limb neurological examination
- Signs of other conditions associated with incontinence(eg diabetes, neuropathy, cerebro vascular disease, parkinson’s disease)
Risk factors for overactive bladder syndrome?
Non-modifiable risk factors:
* Age
* Female
* Metabolic syndrome
* Post menopausal
* Benign prostatic hyperplasia
* Pelvic organ prolapse in women
Modifiable risk factors
* Alcohol
* Smoking
* Obesity
* Caffeine intake
* Carbonated beverages
* Spicy foods
* Bladder stones
Differentials for overactive bladder?
Neurological (neurogenic detrusor overactivity):
* Stroke
* Multiple sclerosis
* Dementia
* Diabetic neuropathy
* Spina bifida
* Spinal trauma
* Reversed diurnal rhythm
Malignancy
* Urothelial carcinoma
Lower urinary tract
* Recurrent urinary tract infection
* Bladder outlet obstruction (Including benign prostatic hyperplasia, urethral stricture)
* Foreign body in lower urinary tract’s (eg eroded synthetic mesh)
* Overflow incontinence
Systemic pathologies
* Obstructive sleep apnea
* Congestive heart failure
* Diabetes resulting in polyuria
Medications
* Diuretics
* Anticholinergics
* Narcotics
Management for overactive bladder?
Non-pharmacological:
* Treatment of modifiable risk factors eg weight reduction
* Reduction of exposure to bladder stimulants (eg alcohol, caffeine, smoking, carbonated beverages)
* Constipation avoidance - aiming for soft stools passing every one to two days, increasing daily fibre intake, using stool softeners and laxatives
* Fluid optimization - Restricting fluid intake to 6-8 glasses of water per day, avoiding prepared hydration by two hours
* Pelvic floor exercises bladder training with physiotherapy
* Containment devices eg incontinence pads
* Bladder training - Scheduling voiding times, using urge control techniques
Pharmacological:
* Topical estrogen - post menopausal female
* Anticholinergic, nonselective - oxybutynin
* Anticholinergic, M3 selective - solifenacin
* Beta 3 agonist - mirabegron
Non-pharmacological management of urge urinary incontinence?
- Advise appropriate fluid intake of 15 to two litres per day
- Advise limit caffeine intake
- Advise to avoid constipation
- Advise regular toileting
- Advise good posture when toileting
- Advise to allow adequate time for emptying when toileting
- Advise bladder retraining programme
- Advise pelvic floor exercises
- Advice the use of incontinence products
- Advice use of mobility aids
- Advise the use of toileting aids (bedside commode)
- Advise to plan her outings by identifying local toilets
Differentials for pelvic discomfort, mildly tender uterus anne milky vagina discharge?
- STI infection: Pelvic inflammatory disease / Chlamydia / Gonorrhoea
- Non-STI infection: Bacterial vaginosis / vagina thrush / simplex virus
- Ectopic pregnancy
- Ovarian Torsion
- Endometriosis
Pharmacological management for pelvic inflammatory disease?
- Ceftriaxone 500mg in 2mL of 1% lidocaine IM
- Metronidazole 400mg BD PO for 14 days
- Doxycycline 100mg BD PO for 14 days
- Paracetamol or NSAID (ibuprofen)
Non-pharmacological management of pelvic inflammatory disease?
- Contact tracing for any partner in the last six months
- Avoid alcohol was metronidazole
- Avoid sexual intercourse for one week following completion of treatments Or until symptomatically better
- Review after three to seven days to ensure response to treatment
- Arranged test of cure after three to four weeks
- Advice regarding barrier contraception such as condoms
- Provide fact sheet regarding pelvic inflammatory disease
Typical presentation of pelvic inflammatory disease?
- Bilateral pelvic pain but may localise to right or left iliac fossa
- Deep dyspareunia
- Abnormal bleeding or discharge
- Cervical motion tenderness
- Fever, nausea, vomiting
Possible causes of pelvic inflammatory disease?
- Polymicrobial
- Sexually transmitted infections eg neisseria gonorrhoea, chlamydia trachomatis, mycoplasma genitalium
- Vaginal facultative bacteria and other vaginal bacteria associated with bacterial vaginosis
- Disruption of the cervical epithelium eg intrauterine device insertion
Pharmacological treatment of uncomplicated genital or pharyngeal chlamydia?
- First line: Doxycycline 100mg BD PO for 7 days
- Second line: Azithyromycin 1g PO STAT
Pharmacological treatment of asymptomatic anorectal chlamydia?
- First line: Doxycycline 100mg BD PO for 7 days
- Second line: Azithyromycin 1g PO STAT, then repeat in 12-24 hours
Pharmacological treatment of symptomatic anorectal chlamydia?
- First line: Doxycycline 100mg BD PO for 21 days
- Second line: Azithyromycin 1g PO STAT, then repeat in 12-24 hours
Which chlamydia patients should get a test of cure atleast 3 weeks after starting treatment?
- Pregnant
- Anorectal infection
- PID
What examination features do you search for when assessing erectile dysfunction?
- Penile plaques
- Small testicular size; low testicular volume - signs of androgen deficiency
- Lack of secondary sexual characteristics (eg lack of hair)
- Weak peripheral pulses
- Enlarged prostate
- Lower limb neurological deficits (eg anal tone, reflexes)
- Penile sensation
- Breast enlargement, gynecomastia
- Obesity
Initial investigations for erectile dysfunction?
- Fasting blood glucose
- Follicle stimulating hormone
- Lipid profile
- Liver function tests - NASH/MAFLD
- Luteinising hormone
- Morning testosterone
- Prolactin
Non-pharmacological management for erectile dysfunction?
- Increase exercise
- Refer to a psychologist; psychotherapist; sex therapist
- Appropriate dietary advice - Mediterranean diet
- Referral to physiotherapist for pelvic floor exercises
- Consideration of penile pump use
- Shared decision making/couple therapy
Management of acute paraphimosis?
- Arrange for transfer to emergency department of a hospital with urology specialist cover by ambulance
- Anaesthetise the penile head eg local anaesthetic topical, penile nerve block, ring block
- Apply circumferential pressure to the glans of the penis to disperse oedema (eg gloved hand or cling film or compression bandage)
- Apply ice intermittently to the head of the penis to reduce the swelling
- Aspiration of blood from the head of the penis with a needle
- Apply granulated sugar to the head of the penis
Risk factors for erectile dysfunction?
- Increased age
- Cardiovascular disease and its risk factors: sedentary lifestyle, obesity, diabetes, hypertension, dyslipidaemia, obstructive sleep apnoea, smoking
- Endocrine: diabetes, androgen deficiency, thyroid disorders, hyperprolactinaemia
- Neurological: brain, spinal cord, or autonomic nervous system
- Medication: beta blockers, thiazides, antidepressants, antipsychotics, antiandrogens
- Prostate cancer therapy
- Penile disorders: Peyronie disease
- Recreational drug or alcohol use
Management options for erectile dysfunction?
Optimise modifiable risk factors and related comorbidities
* Lifestyle - smoking cessation, healthy diet, exercise, reduce alcohol intake, avoid recreational drugs
* Reinforce blood pressure, dyslipidemia, diabetes control
* Assessable cardiovascular disease
Treat reversible causes
* Low testosterone
* Medication induced erectile dysfunction - Consider alternatives
* Psychogenic erectile dysfunction - consider referral to a therapist
First line therapy: phosphodiesterase type 5 inhibitor
Referral to Urologist
* Second line: penile injections, vacuum erection devices, external shock wave lithotripsy
* Third line: penile prosthesis
Pharmacological management options for bone pain from bony metastases?
- Paracetamol
- Non steroidal anti inflammatory
- Opioid
- Bisphosphonate therapy: pamidronate, zoledronic acid
- Glucocorticoid therapy: dexamethasone
- Stool softening agents
What advice would you provide if a patient was concerned about Future loss of capacity to make decisions relating to their health care?
- Prepare an advance health directive; advance care plan; living well
- Appoint a Medical Enjuring Power of Attorney
- Appoint an Enduring Guardian
What are some signs and symptoms of hypercalcemia?
- Confusion/delirium
- Nausea and vomiting
- Pain
- Constipation
- Thirst
- Polyurea
Management actions for a young female sexual assault victim from two days ago who was released from prison weeks ago. No contraception. Intermittently used Intravenous heroin. She does not consent for further physical examination
- Offer referral to sexual assault referral centre
- Offer emergency contraception: levonorgestrel, ulipristal
- Refer to sexual assault community support group or counsellor
- Offer empirical sexually transmitted infection treatment
- Undertake sexually transmitted infection investigation screen
- Offer human immunodeficiency virus post exposure prophylaxis
- Provide education regarding safe needle use
- Offer referral to drug and alcohol service
- Undertake mental health assessment and suicide risk assessment
- Offer referral to homeless support service
Non pharmacological management for aggressive behaviour in an elderly patient In a nursing home?
- Identify and reduce triggers of his aggression
- Anxiety management techniques (eg reassurance, talking about anxiety provoking thoughts, cognitive interventions)
- Provide calm, low stimulating environments
- Simplify instructions (Ie clear, concise, neutral volume/tone) when conversing
- Offer positive reinforcement for good behaviour
- Provide familiar environment (eg photos of family, consistent staff/routine)
- Time orientation aids (eg whiteboards with instructions routine, clocks in vision, offering natural light during daytime)
- Touch therapies (eg massage, acupuncture)
- Integrate regular leisure activities (eg arts, craft, gardening)
What are some possible causes of erythema multiforme?
- Food additives/food allergy
- Idiopathic
- Infection - Eg herpes/hepatitis and other viruses, tuberculosis, leprosy, fungal infection, mycoplasma
- Neoplasia - eg hodgkin’s disease, myeloma, carcinoma
- Medications - Eg sulphonamides, barbiturates, penicillin, anticonvulsants
- Systemic disease eg systemic lupus erythematosus