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Immunology & Serology > 01 Introduction > Flashcards

01 Introduction Flashcards

1
Q

Substance capable of inducing an immune response

A

Antigen

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2
Q

Antigen that is not intrinsically present in the human body

A

Foreign/Non-self antigen

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3
Q

Antigen that is an intrinsic part of the human body

A

Self Antigen

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4
Q

Antigens in nucleated cells that are matched prior to organ transplantation

A

Human Leukocyte Antigen (HLA)

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5
Q

Antigens in anucleated cells that are matched prior to blood transfusion

A

Blood Group Antigen

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6
Q

Capacity of the immune system to differentiate self from non-self, harmless from harmful

A

Tolerance

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7
Q

Exaggerated response of the immune system towards harmless antigens

A

Hypersensitivity Reaction

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8
Q

Antigen that triggers hypersensitivity reaction

A

Allergen

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9
Q

The immune system attacks and destroys self antigens due to its inability to distinguish self from non-self

A

Autoimmune disease

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10
Q

Antibodies that attack self-antigens

A

Autoantibodies

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11
Q

Antinuclear antibodies attack the components of the nucleus of the cells in the body

A

Systemic Lupus Erythematosus (SLE)

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12
Q

Common cause of death of SLE patients

A

Kidney failure

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13
Q

Cancer of the bone marrow results in the release of immature blood cells into circulation

A

Immunoproliferative disease

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14
Q

High cell count, mostly blast cells in the blood

A

Leukemia

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15
Q

High cell count, mostly blast cells in the lymphoid organs

A

Lymphoma

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16
Q

Due to decrease leukocyte count or decreased leukocyte function

A

Immunodeficiency disorder

17
Q

Field of immunology concerning cells that destroy cancerous cells

A

Tumor Immunology

18
Q

Antigens expressed by cancer cells in abnormal levels

A

Tumor markers

19
Q

Tumor marker for pancreatic cancer

A

CA 19-9

20
Q

Tumor marker for ovarian cancer

A

CA 15-3

21
Q

Tumor marker for colorectal cancer

A

Carcinoembryonic antigen (CEA)

22
Q

Matching of HLAs prior to organ transplantation

A

Transplantation Immunology

23
Q

Method of manipulating the immune system via introduction of attenuated organism into the body

A

Vaccination / Immunization

24
Q

Ability to cause disease

A

Pathogenicity

25
Q

Ability to stimulate antibody production

A

Immunogenicity

26
Q

Study of antigen-antibody reaction

A

Serology

27
Q

Antibodies react with different but closely related antigen

A

Cross reactivity

28
Q

Immunoassays, Immunofluorescense, Chemiluminescence

A

Primary Reactions

29
Q

Agglutination, Precipitation, Flocculation, Complement-fixation

A

Secondary Reactions

30
Q

In vivo tests

A

Tertiary Reactions

31
Q

Primary sample used in serology

A

Serum

32
Q

Study of the immune system

A

Immunology

Immunology & Serology (2 decks)

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