01 Flashcards

1
Q

cell division stages:

A

interphase
early prophase
late prophase
metaphase
anaphase
telophase
interphase

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2
Q

types of cell division

A

mitosis and meiosis

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3
Q

only splits into two

A

mitosis

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4
Q

splits into four

A

meiosis

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5
Q

mitosis process:

A

prophase
prometaphase
metaphase
anaphase
telophase

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6
Q

meiosis process:

A

prophase 1
metaphase 1
anaphase 1
telophase 1
prophase 2
metaphase 2
anaphase 2
telophase 2

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7
Q

result either from errors
in DNA replication or from the
damaging effects of mutagens,
such as chemicals and radiation,
which react with DNA and change
the structures of individual
nucleotides

A

mutations

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8
Q

is the highly condensed form of
DNA

A

chromosome

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9
Q

when does chromosome shape into its familiar shape X?

A

metaphase

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10
Q

humans have how many autosomal pairs?

A

22

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11
Q

how many pairs of sex chromosomes do humans have?

A

1

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12
Q

Study of chromosomes and chromosomal abnormalities

A

cytogenetics

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13
Q

picture of an individual’s chromosomes in Metaphase, spread out on a slide

A

study karyotypes

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14
Q

– More condensed
– Silenced genes (methylated)
– Gene poor (high AT content)
– Stains darker

A

heterochromatin

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15
Q

– Less condensed
– Gene expressing
– Gene rich (higher GC content)
– Stains lighter

A

euchromatin

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16
Q

– chromosome tips
– Repeats
– Act as sort of biological clock
– Being whittled down at each Mitosis

17
Q

– middle
– Highly condensed
– Also repetitive sequence
– Region where spindle fibers attach
– Pulling chromatids apart during Mitosis

A

centromeres

18
Q

the smaller of the two arms
– p stands for petite

19
Q

the longer of the two arms

20
Q

chromosome parts:

A

heterochromatin
euchromatin
telomeres
centromeres
p arm
q arm

21
Q

4 types of chromosomes:

A
  1. Telocentric
  2. Acrocentric
  3. Submetacentric
  4. Metacentric
22
Q

no p arm; centromere is on end

A

telocentric

23
Q

no p arm; centromere is on end

A

acrocentric

24
Q

p arm just a little smaller than q arm;
centromere in middle

A

submetacentric

25
Q

p and q arms are exactly the same length; centromere in exact middle of chromosome

A

metacentric

26
Q

what chromosomes are not identical
and can have different alleles of genes

A

homologous

27
Q

what are identical
– Form as cells go through S phase (replication)
– Attached to each other by centromere
– Until Anaphase of Mitosis
– Once separated each is again referred to as a chromosome

A

sister chromatids

28
Q

– Two q arms of two different chromosomes come together
– Two p arms are lost entirely

A

robertsonian translocation

29
Q

– Two different chromosomes exchange parts
– Since all parts are still present – often normal

A

reciprocal translocation

30
Q

types of translocations:

A

robertsonian and reciprocal

31
Q

one chromosome absent is called?

31
Q

one chromosome extra is called?

32
Q

When nondisjunction occurs in both themother and the father’s gametes

Causing two copies of one chromosome to come only from one parent

A

uniparental disomy