008 An overview of Diabetes Mellitus

Question 1

Which ethnic group is most susceptible to diabetes mellitus?

Answer 1

Afrocarribean
Indian
East Asian

Question 2

What is the prevalance of DM in the population??

Answer 2

1/4 people have DM

Question 3

FPG diagnosis

Answer 3

> 7 mmol/L

Question 4

RPG diagnosis

Answer 4

> 11.1 mmol/L

Question 5

75g 2 hr OGTT diagnosis

Answer 5

> 11.1 mmol/L

Question 6

HbA1c diagnosis

Answer 6

> 6.5% (48mmol/L)

Question 7

How frequent do diabetics develop foot ulcers?

Answer 7

15% of diabetic patients

Question 8

What is the BMI cut off for bariatric surgery?

Answer 8

35

Question 9

What is the main form of bariatric surgery?

Answer 9

Gastric bypass or gastric sleeve

Question 10

What does Metformin do?

Answer 10

Increases glucose uptake and reduces glucose production

Question 11

What does Sulphonylureas do?

Answer 11

Stimulates insulin secretion

Question 12

What are Gliptins

Answer 12

Increases blood concentration of GLP1

Question 13

What are Gliflozins

Answer 13

These are SGLT2 inhibitors that reduce glucose uptake in the kidney and increases its disposal

Question 14

What are a-glucosidase inhibitors

Answer 14

These delay the absorption of glucose but gut intake

Question 15

What do GLP1 analgues do

Answer 15

These stimulate insulin secretions

Question 16

What drugs can help insulin sensitization?

Answer 16

Thiazolidinediones

Question 17

If someone is not sensitive to HbA1c testing, what can be used?

Answer 17

Fructosamine