0-1 Chapter 16 - sense Organs Flashcards
sense organs
nerve tissue surrounded by other tissues that enhance response to certain type of stimulus
•added epithelium, muscle or connective tissue
transduction
the conversion of one form of energy to another
–fundamental purpose of any sensory receptor
receptor potential
small, local electrical change on a receptor cell brought about by an initial stimulus
•results in release of neurotransmitter or a volley of action potentials that generates nerve signals to the CNS
sensation
a subjective awareness of the stimulus
–most sensory signals delivered to the CNS produce no conscious sensation
Receptors Transmit Four Kinds of Information
Modality
Location
Intensity
Duration
Modality
type of stimulus or the sensation it produces
–vision, hearing, taste
labeled line code
all action potentials are identical. Each nerve pathway from sensory cells to the brain is labeled to identify its origin, and the brain uses these labels to interpret what modality the signal represents
Location
encoded by which nerve fibers are issuing signals to the brain
receptive field
area that detects stimuli for a sensory neuron
sensory projection
brain identifies site of stimulation
projection pathways
the pathways followed by sensory signals to their ultimate destination in the CNS
Intensity
encoded in 2 ways
Strength
frequency
Duration
how long the stimulus lasts
sensory adaptation
if stimulus is prolonged, the firing of the neuron gets slower over time, and we become less aware of the stimulus
phasic receptor
generate a burst of action potentials when first stimulated, then quickly adapt and sharply reduce or stop signaling even though the stimulus continues
tonic receptor
adapt slowly, generate nerve signals more steadily
Classification of Receptors by
modality
origin of stimuli
distribution
by modality
–thermoreceptors, photoreceptors, nociceptors, chemoreceptors, and mechanoreceptors
origin of stimuli
–exteroceptors -detect external stimuli
–interoceptors -detect internal stimuli
–proprioceptors -sense body position and movements
by distribution
–general (somesthetic) senses -widely distributed
–special senses -limited to head
•vision, hearing, equilibrium, taste, and smell
General Senses
structurally simple receptors
–one or a few sensory fibers and a little connective tissue
unencapsulated nerve endings
•dendrites not wrapped in connective tissue
–free nerve endings
–tactile (Merkel) discs
–hair receptors (peritrichial endings
free nerve endings
–for pain and temperature
–skin and mucous membrane
tactile discs
–for light touch and texture
–associated with Merkel cells at base of epidermis
hair receptors
–wrap around base of hair follicle
–monitor movement of hair
encapsulated nerve endings
- dendrites wrapped by glial cells or connective tissue
* connective tissue enhances sensitivity or selectivity of response
encapsulated nerve endings
types
–tactile (Meissner) corpuscles –Krause end bulbs –bulbous (Ruffini) corpuscles –lamellar (pacinian) corpuscles –muscle spindles –golgi tendon organs
tactile (Meissner) corpuscles
–light touch and texture
–dermal papillae of hairless skin
Krause end bulb
–tactile; in mucous membranes
lamellated (pacinian) corpuscles
phasic
–deep pressure, stretch, tickle and vibration
–periosteum of bone, and deep dermis of skin
bulbous (Ruffini) corpuscles
tonic
–heavy touch, pressure, joint movements and skin stretching
Sound receptors are
mechanoreceptors
Somesthetic Projection Pathways
from receptor to final destination in the brain, most somesthetic signals travel by way of three neurons
1st order neuron (afferent neuron)
–from body, enter the dorsal horn of spinal cord via spinal nerves
–from head, enter pons and medulla via cranial nerve
–touch, pressure and proprioception on large, fast, myelinated axons
–heat and cold on small, unmyelinated, slow fibers
2nd order neuron
–decussation to opposite side in spinal cord, medulla, or pons
–end in thalamus, except for proprioception, which ends in cerebellum
3rd order neuron
–thalamus to primary somesthetic cortex of cerebrum
pain
discomfort caused by tissue injury or noxious stimulation, and typically leading to evasive action
–important since helps protect us
nociceptors
two types providing different pain sensations
fast pain
travels in myelinated fibers at 12 -30 m/sec
•sharp, localized, stabbing pain perceived with injury
slow pain
travels unmyelinated fibers at 0.5 -2 m/sec
•longer-lasting, dull, diffuse feeling
somatic pain
from skin, muscles and joints
visceral pain
from the viscera
–stretch, chemical irritants or ischemia of viscera (poorly localized
bradykinin
most potent pain stimulus known
–makes us aware of injury and activates cascade or reactions that promote healing
Projection Pathway for Pain
two main pain pathways to brain, and multiple subroutes
first-order neuron cell bodies
in dorsal root ganglion of spinal nerves or cranial nerves V, VII, IX, and X
spinothalamic tract
most significant pain pathway
–carries most somatic pain signals
spinoreticular tract
carries pain signals to reticular formation
–activate visceral, emotional and behavioral reactions to pain
referred pain
pain in viscera often mistakenly thought to come from the skin or other superficial site
analgesic
(pain-relieving) mechanisms of CNS just beginning to be understood
enkephalins
two analgesic oligopeptides with 200 times the potency of morphine
endogenous opioids
internally produced opium-like substances
•enkephalins, endorphins, and dynorphins
neuromodulators
neuromodulators that can block the transmission of pain signals and produce feelings of pleasure and euphoria
spinal gating-
stops pain signals at the posterior horn of the spinal cord
SEE DIAGRAM
spinal gating-
rubbing or massaging injury
•pain-inhibiting neurons of the posterior horn receive input from mechanoreceptors in the skin and deeper tissues
–rubbing stimulates mechanoreceptors which stimulates spinal interneurons to secrete enkephalins that inhibit second-order pain neurons
gustation
(taste) –sensation that results from action of chemicals on taste buds
MUST BE LIQUID TO TASTE
taste buds - location
4000 -taste buds mainly on tongue
–inside cheeks, and on soft palate, pharynx, and epiglottis
lingual papillae
4 areas
filiform
foliate
fungiform
vallate (circumvallate)
filiform
no taste buds
•important for food texture
foliate
no taste buds
•weakly developed in humans
fungiform
•at tips and sides of tongue
vallate (circumvallate)
- at rear of tongue
* contains 1/2 of all taste buds
taste cells
synapse with and release neurotransmitters onto sensory neurons at their base
Have: taste hairs, taste pores,
taste hairs
have tuft of apical microvilli(taste hairs) that serve as receptor surface for taste molecules
taste hairs are epithelial cells not neurons
taste pores
pit in which the taste hairs project
basal cells
stem cells that replace taste cells every 7 to 10 days
supporting cells
resemble taste cells without taste hairs, synaptic vesicles, or sensory role
Physiology of Taste
to be tasted, molecules must dissolve in saliva and flood the taste pore
five primary sensations
salty –sweet –sour –bitter –umami
mouthfeel
detected by branches of lingual nerve in papillae
two mechanisms of action
activate 2nd messenger systems
depolarize cells directly
either mechanism results in release of neurotransmitters that stimulate dendrites at base of taste cells
activate 2nd messenger systems
•sugars, alkaloids, and glutamate bind to receptors which activates G proteins and second-messenger systems within the cell
depolarize cells directly
sodium and acids penetrate cells and depolarize it directly
Projection Pathways for Taste
- facial nerve, glossopharyngeal nerve, vagus nerve
- all fibers reach solitary nucleus in medulla oblongata
- signals sent two destinations: hypothalamus and amygdala or Thalamus
facial nerve
collects sensory information from taste buds over anterior two-thirds of tongue
glossopharyngeal nerve
from posterior one-third of tongue
vagus nerve
from taste buds of palate, pharynx and epiglottis
hypothalamus and amygdala
control autonomic reflexes –salivation, gagging and vomiting
thalamus
relays signals to postcentral gyrus of cerebrum for conscious sense of taste
orbitofrontal cortex
sent on to orbitofrontal cortex to be integrated with signals from nose and eyes -form impression of flavor and palatability of food
olfaction
sense of smell
olfactory mucosa
–contains 10 to 20 million olfactory cells, which are neurons, as well as epithelial supporting cells and basal stem cells
–mucosa of superior concha, nasal septum, and roof of nasal cavity covering about 5 cm2
olfactory cells
–are neurons
–shaped like little bowling pins
only neurons in the body directly exposed to the external environment
–have a lifespan of only 60 days
olfactory hairs
head bears 10 –20 cilia called olfactory hairs
–have binding sites for odorant molecules and are nonmotile
–lie in a tangled mass in a thin layer of mucus
axons collect into small fascicles and leave cranial cavity through
the cribriform foramina in the ethmoid bone
fascicles are collectively regarded as
Cranial Nerve I
olfactory receptors adapt
quickly
–due to synaptic inhibition in olfactory bulbs
PHASIC
Human Pheromones
–human body odors may affect sexual behavior
olfactory cells synapse in
olfactory bulb
–on dendrites of mitral and tufted cells
glomeruli
dendrites meet in spherical clusters called glomeruli
•each glomeruli dedicated to single odor because all fibers leading to one glomerulus come from cells with same receptor type
tufted and mitral cell axons form
olfactory tracts
–reach primary olfactory cortex in the inferior surface of the temporal lobe
Hearing and Equilibrium
both senses reside in the inner ear, a maze of fluid-filled passages and sensory cells
•fluid is set in motion and how the sensory cells convert this motion into an informative pattern of action potentials
hearing
a response to vibrating air molecules
equilibrium
the sense of motion, body orientation, and balance
sound
any audible vibration of molecules
–a vibrating object pushes on air molecules
–in turn push on other air molecules
–air molecules hitting eardrum cause it to vibration
pitch
our sense of whether a sound is „high‟ or „low‟
–determined by the frequency
infrasonic
infrasonic frequencies below 20 Hz
ultrasonic
ultrasonic frequencies above 20,000 Hz
loudness
the perception of sound energy, intensity, or amplitude of the vibration
–expressed in decibels (dB)
–prolonged exposure to sounds > 90dB can cause damage
ear has three sections
outer, middle, and inner ear
–first two are concerned only with the transmission of sound to the inner ear
–inner ear –vibrations converted to nerve signals
outer ear
a funnel for conducting vibrations to the tympanic membrane (eardrum)
auricle
(pinna) directs sound down the auditory canal
•shaped and supported by elastic cartilage
auditory canal
passage leading through the temporal bone to the tympanic membrane
external acoustic meatus
slightly s-shaped tube that begins at the external opening and courses for about 3 cm
guard hairs
protect outer end of canal
cerumen
earwax) –mixture of secretions of ceruminous and sebaceous glands and dead skin cells
–sticky and coats guard hairs
–contains lysozyme with low pH that inhibits bacterial growth
–water-proofs canal and protects skin
–keeps tympanic membrane pliable
middle ear
located in the air-filled tympanic cavity in temporal bone
tympanic membrane
(eardrum) –closes the inner end of the auditory cana
•innervated by sensory branches of the vagus and trigeminal nerves
–highly sensitive to pain
tympanic cavity
is continuous with mastoid air cells
auditory (eustachian) tube
connects middle ear cavity to nasopharynx
•equalizes air pressure on both sides of tympanic membrane
auditory ossicles
malleus
incus
stapes