פסיכומפרמקולוגיה - תרופות Flashcards

1
Q

L-Dopa

A

agonist for dopamine, goes through barrier

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2
Q

monosodium glutamate

A

indirect agonist for glutamate

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3
Q

AMPT

A

antagonits for L-Dopa by blocking enzyme that produces it from tyrosine, therefore anti to all catecholamines (dop, epi, norepi)

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4
Q

PCPA

A

antagonist to Serotonin by blocking its procusing enzyme

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5
Q

Reserpine

A

anta- blocks monoamines from entering vesicles, thus their uptake

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6
Q

Black widow spider venom

A

ACh agonist to its realese from buttons

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7
Q

Butulinium toxin

A

botox, ACh antagonist by preventing release

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8
Q

Nicotine

A

Direct ACh agonist - nicotinic ionoreceptor

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9
Q

Muscarine

A

Direct ACh agonist - Muscarinic metareceptor

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10
Q

LSD

A

Direct serotonin agonist

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11
Q

Curare

A

Direct antagonist of ACh by blockin nicotinic receptor

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12
Q

Atropine

A

Direct antagonist of ACh by blockin Muscarinic receptor

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13
Q

Sarin

A

ACh agonist by blocking AChE and expanding synapse expusure

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14
Q

Caffeine

A

Andenosine direct antagonist

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15
Q

PCP (angel dust)

A

Indirect glutamate agonist because it has a MNDA binding site

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16
Q

Benzodiazepine

A

Indirect GABA agonist because it has GABAa binding site

17
Q

Cocaine

A

blocks dopamine reuptake transporter - indirect agonist by promoting exposure

18
Q

Hemicholine

A

blocks choline uptake -there for ACh antagonist by blocking its sytethis in the cell.

19
Q

Ritalin (Methylphenidate)

A

cathecolamine (dopamine and norepineprine) indirect agonist by preventing reuptake

20
Q

Amphetamine (‘speed’)

A

monoamine indirect agonist by blocking reuptake

21
Q

Fluoxetine (Prozac)

A

SSRI - blocks serotonin reuptke therfor indirect agonist

22
Q

MDMA (‘Ecstasy’)

A

Indirect serotonin an norepinephrine agonist by blocking reuptake

23
Q

Neostigmine

A

Binds to AChE and prevents it’s action, therfore ACh indirect agonist.

24
Q

Apomorphine

A

indirect dopamin antagonist by stimulating autoreceptors

25
Q

idazoxan

A

blocks norepinephrine autoreceptor therefor it’s indirect agonist.