פסיכומפרמקולוגיה - תרופות Flashcards
L-Dopa
agonist for dopamine, goes through barrier
monosodium glutamate
indirect agonist for glutamate
AMPT
antagonits for L-Dopa by blocking enzyme that produces it from tyrosine, therefore anti to all catecholamines (dop, epi, norepi)
PCPA
antagonist to Serotonin by blocking its procusing enzyme
Reserpine
anta- blocks monoamines from entering vesicles, thus their uptake
Black widow spider venom
ACh agonist to its realese from buttons
Butulinium toxin
botox, ACh antagonist by preventing release
Nicotine
Direct ACh agonist - nicotinic ionoreceptor
Muscarine
Direct ACh agonist - Muscarinic metareceptor
LSD
Direct serotonin agonist
Curare
Direct antagonist of ACh by blockin nicotinic receptor
Atropine
Direct antagonist of ACh by blockin Muscarinic receptor
Sarin
ACh agonist by blocking AChE and expanding synapse expusure
Caffeine
Andenosine direct antagonist
PCP (angel dust)
Indirect glutamate agonist because it has a MNDA binding site
Benzodiazepine
Indirect GABA agonist because it has GABAa binding site
Cocaine
blocks dopamine reuptake transporter - indirect agonist by promoting exposure
Hemicholine
blocks choline uptake -there for ACh antagonist by blocking its sytethis in the cell.
Ritalin (Methylphenidate)
cathecolamine (dopamine and norepineprine) indirect agonist by preventing reuptake
Amphetamine (‘speed’)
monoamine indirect agonist by blocking reuptake
Fluoxetine (Prozac)
SSRI - blocks serotonin reuptke therfor indirect agonist
MDMA (‘Ecstasy’)
Indirect serotonin an norepinephrine agonist by blocking reuptake
Neostigmine
Binds to AChE and prevents it’s action, therfore ACh indirect agonist.
Apomorphine
indirect dopamin antagonist by stimulating autoreceptors
idazoxan
blocks norepinephrine autoreceptor therefor it’s indirect agonist.
