Zollinger-Ellison syndrome Flashcards
1
Q
Pathophysiology?
A
There are excessive levels of gastrin, usually from a gastrin secreting tumour usually of the duodenum or pancreas.
2
Q
Associated with which condition?
A
30% occur as part of MEN type I syndrome
3
Q
Symptoms?
A
- multiple gastroduodenal ulcers
- diarrhoea
- malabsorption
4
Q
Diagnostic tests?
A
- fasting gastrin levels: the single best screen test
- secretin stimulation test
