Ziolo Midterm Flashcards

1
Q

Hematocrit

A

RBC/Total blood volume

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2
Q

Microcirculation

A

arterioles, capillaries, venules

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3
Q

Force

A

DeltaP/R

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4
Q

Resistance

A

8(Length)(viscosity)/pi(r^4)

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5
Q

Most important factor in resistance

A

radius

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6
Q

Innervation of the atria

A

Parasympathetic and Sympathetic

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7
Q

Innervation of ventricle

A

Sympathetic ONLY

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8
Q

SA Node

A

Pacemaker of heart

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9
Q

Heart Conduction System

A

SA-AV-Bundle of His- Right and Left Bundle Branches- Perkinje Cells

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10
Q

Depolarization phase of myocardial ventricular cell

A

Opening of Na+ channels

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11
Q

Plateau of myocardial ventricular cell

A

Opening of calcium and potassium channels

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12
Q

Repolarization phase of myocardial ventricular cell

A

Opening of potassium channels, closure of calcium

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13
Q

F Channels

A

Leaky Sodium Channels in nodal cells

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14
Q

Depolarization in nodal cell

A

opening of calcium channels

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15
Q

repolarization in nodal cell

A

reopening of potassium channels, closure of calcium

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16
Q

P Wave

A

Atrial depolarization

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17
Q

QRS complex

A

ventricular depolarization

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18
Q

T Wave

A

ventricular repolarization

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19
Q

L Type Channels

A

calcium channels in plasma membrane that allow calcium to flow into cytosol

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20
Q

Why do we need a long refractory period in heart?

A

ventricular filling

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21
Q

First heart sound

A

closure of AV valves

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22
Q

Second heart sound

A

closure of aortic an pulmonary valves

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23
Q

Stenosis

A

narrowing

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24
Q

regurgitation

A

insufficiency

25
How are systemic and pulmonary systems arranged?
in series
26
How are organ systems arranged?
in parallel
27
Systole
ventricles contracting
28
diastole
ventricles relaxed
29
Cardiac Output
HR x SV
30
Stroke Volume
amount of blood ejected per cycle; EDV-ESV
31
How to speed up heart rate
increase sympathetic innervation, decrease parasympathetic
32
3 Factors influencing SV
Pre-load, Afterload, sympathetic input
33
Frank Starling Mechanism
Illustrates effects on stroke volume
34
How do sympathetics influence contraction and relaxation of heart
Stronger and more rapid contraction and more rapid relaxation
35
How do sympathetics increase SV
by increasing calcium
36
Compliance
deltaV/deltaP
37
Pulse Pressure
SP-DP
38
MAP
DP + 1/3(SP-DP)
39
Sympathetic Stimulation to alpha adrenergic receptors
vasoconstriction; less blood supply
40
Sympathetic Stimulation to beta adrenergic receptors
vasodilation; increase blood supply to that area
41
Do capillaries have smooth muscles
No, punk
42
Filtration
movement of fluid and solutes out of blood
43
Absorption
movement of fluid and solutes into blood
44
Hydrostatic pressure
outward force away from the fluid
45
Osmotic force due to plasma protein concentration
inward force pulling fluid towards it
46
Erythropoietin
release by kidneys in response to low oxygen to signal production of more erythrocytes in bone marrow
47
Anemia
decreased ability of blood to carry oxygen due to decreases total number of erythrocytes or diminshed concentration of hemoglobin
48
2 processes of hemostasis
platelet plug formation and coagulation
49
most important factor for clotting
thrombin
50
Why is liver important in clotting
help absorb vit K which is needed to make prothrombin
51
Protein C, TFPI, and Antithrombin III
limit clotting
52
Total Peripheral Resistance
sume of resistance from all systemic blood vessels
53
MAP
CO x TPR= Mean Systemic Arterial Pressure
54
Barroreceptors
monitor blood pressure, especially in aortic arch and carotid sinuses
55
Main reason CO increases during excercise
HR
56
Shock
any situation with decrease in blood to organs; can be hypovolemic, low-resistance, or cardiogenic
57
Ischemia
Atherosclerotic narrowing of coronary artery resulting in decreased blood supply to myocardium
58
Infarction
when severe ischemia causes myocardial damage
59
Angina pectoris
chest pain associated with ischemia or infarction