year 4 cap test Flashcards

1
Q

muscle rigidity , pyrexia, agitation, autonomic instability. when atyipical antipsychotics have been used (+ physical restraint needed)

A

neuroleptic malignant syndrome

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2
Q

parkinsinonsim is a common side effect of

A

antiphsychotics

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3
Q

average onset of biploar

A

21

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4
Q

first place affected in alzheimers

A

nucleus basalis of meynert

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5
Q

paraproteins is a tumour marker for what

A

myeloma

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6
Q

ovarian cancer tumour marker

A

CA 125

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7
Q

aversive and defence systems

A

seretonin

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8
Q

aqueous humour drains via what

A

trabecular meshwork

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9
Q

otosclerosis- type of hearing loss?

A

conductive

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10
Q

type of hearing loss for gentamicin , loud noise exposure, vestibular shwannoma?

A

sensorineural

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11
Q

what bloods do you need to monitor for metformin

A

U&E and HbA1c

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12
Q

pain out of proportion

A

compartment syndrome

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13
Q

small bleed after rupture of membranes with severe fetal distres

A

vasa praevia

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14
Q

IQ of 45

A

moderate learning disability

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15
Q

most abundant antibody

A

IgG

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16
Q

antobody in breast milk and saliva

A

IgA

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17
Q

pentemeric antibody

A

IgM

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18
Q

what to do for a choking conscious baby

A

do chest thrusts

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19
Q

in polymalgia rheumatica, is there power loss

A

no - power is normal

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20
Q

in polymyositis , is there power loss.

A

yes- will have muscle weakness

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21
Q

appettitive anf approach systems

A

dopamine

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22
Q

cardio drug causing blurred vision

A

digoxin

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23
Q

what bloods do you check if going on lithium

A

U&E

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24
Q

gram neg diplococcus

A

gonorrhoea

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25
Q

used IV drip goes in which bag

A

organge

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26
Q

80 year old lady with hx of falls. rigth knee gives way when walking and she is waiting for a knee replacement. she has been struggling to climb stairs due to her knee. she takes paracetamol and was started on codeine 2 weeks ago. what is the most appropriate action?

A

strength and balance training before knee replacement

doing this before and after surgyer improves quad strength and stability of knee joint. they should be encouraged to exercise whilst waiting on surgery.
NSAIDS would increase risk of renal impairment

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27
Q

is this change correct when ageing?

body weight may remain normal despite reduction in muscle mass?

A

true

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28
Q

68 year old man recently discharged from an MI. does not understand his meds or his conditon.

who does he need to see?

A

specialist nurse

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29
Q

42 year old insulin dependent diabetic has a painful left toe . who should he see?

A

podiatrist

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30
Q

28 year old lady with 4 kids. struggling with their behavioir and has concerns about the youngest one’s growth.
who should she see?

A

health visitor

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31
Q

contraction results in elevation of the section of the resp tract containing the vocal cords

A

longitudinal muscles of the pharynx

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32
Q

located immediately superficial to the transversus abdominus muscle

A

internal oblique

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33
Q

can act as an accessor muscle to respiration due to its attachment to rib 1

A

scalenus

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34
Q

which has the highest mortality- depression, bipolar, schizoaffective disirder, anorxia, or bulimia ?

A

anorexia

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35
Q

brief episodes of vertigo. no tinnitus or hearing loss. usuually occuring on turning in bed

A

BPPV

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36
Q

6 month old infant seen by GP unwell with mild fever, cough, reduced oral intake and noisy breathing for 2 days. on exam there are mild signs of resp distress and sats are 92%. good air entry bilaterally and widely scattered high pitch rhonchi and fine crepitations

A

need to admit for supportive therapy.

this is a classic presentation of bronchilotis caused by RSV

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37
Q

preterm neonate born at 32 weeks becomes floppy and cyanosed. meningitis is suspected. CSF shows gram positive cocci in chains. mum was noticied to be carrying this in her vag.

A

group B strep

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38
Q

40 year old man admitted with confusion and fever. CT scan performed prior to LP shows inflamed temporal lobes.

A

herpes simplex- most common cause of encephalitis. it usually affects the temporal lobes

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39
Q

60 year old immunocompromised patient is admitted with fever and headache. he consumed soft cheese in france about 1 week ago. gram stain of CSF shows gram postive bacilli

A

listeria

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40
Q

patient in neuro clinic complaining of abnormal head movements and neck pain. he notes that his head has a tendency to turn to the left and he finds it uncomfortable

A

cervical dystocia

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41
Q

delay in femoral pulses suggest what

A

congential CVS disease in newborn infant e.g coarctation of aorta

42
Q

30 year old lady with itchy blisters on extensor surfaces. immunofluorescence reveals granular IgA at dermal papillae

A

dermatitis herpetaformis

43
Q

most appropriate drug for a 3 year old undergoing squint surgery who becomes bradycardic and hypotensive during surgical traction

44
Q

most appropriate drug for a 71 year old who suddenly develops AF with rate of 150. BP 125/70. has a hx of COPD and is on regular inhalers

A

amiodarone.

CVS is stable and she doesnt require immediate cardioversion and rate control is more appropriate
beta blockers are contraindicated

45
Q

most appropriate 1st line choice for 42 year old man with acute central chest pain, nausea and sweating for 1 hour. ST elevation ins V1-3

A

clopidogrel

46
Q

most appropraite first line for a 45 year old man with intermittent palpitations and light headedness . on arrival pulse is 100 irreg irreg but after 20 mins is settles to 56 regular

A

bisoprolol is first line

this is paraoxysmal AF

47
Q

gradual vision loss in both eyes. diminished red reflexes

48
Q

sudden painless loss of central vision in right eye. has been aware of distorted vision for past few days. large solitary haemorrhage at the fovea of affected eye

A

wet age related macular degeneration

49
Q

a long sighted 52 year old male presents with sudden loss of vision in left eye with is red and painfil. he has noticed halos around lights and feels nauseated and has vomited once. pupil is mid-dilated and non reactive

A

acute closed angle glaucoma

50
Q

18 year old girl. tired and dizzy. has heavy periods. Hb is low. MCV is 72 and ferritin is low

A

iron def anaemia

51
Q

38 year old man present to AMU with painless jaundice and exterional SOB. he is anaemic with MCV 115. retic ount is high. direct antiglobulin test is strongly positive. blood film shows spherocytes and polychromasia

A

autoimmune haemolytic anaemia

anaemia and jaundice should make you think of hameolysis. bone marrow is working hard to make new red cells

52
Q

62 year old man presents feeling non-specifically unwell and found to be in renal failure with creatinine of 43. he was noted to have back pain for 2 months has a corrcted calcium of 3.6 and IgA paraprotein

A

myeloma!!

bone pain
anaemia
hypercalcaemia
renal failure

53
Q

75 year olf got a dynamic hip screw for a intertrochanteric fracture 9 months ago. she returns to clinic complaining of discomfort on walking . CRP is normal b ut X rays show a somewhat back out dynamic screw

A

trochanteric bursitis from prominant mental work

54
Q

describe innveration to the detrusor muscle

A

sympatethic innerviation is via beta adrengeric recepotos. this relaxes the detrusor whilst contracting the urethral sphincter thereby inhibiting urge to void.

parasympathetic excite the bladder and relax the urethral sphincter, aiding voiding.

55
Q

a patient with fever and cough who you suspect to have TB but lab confirmation awaits.

A

need single room and surgical masks for staff

56
Q

patient with legionella

A

no special precautions needed and not transmissionable from person to person

57
Q

term infant aged 4 days delovered by C section due to pre-eclampsia is noted to be jaundiced. he is breast feeding well

A

physiological jaundice

58
Q

how does lamotrigine work

A

blocks voltage sensitive sodium channels and reduces release of glutamate

59
Q

legal course of action for a woman with severe dementia unable to make finance decisons. her nephew is financial power of attorney but is discovered to be taking her money to pay his morgage

A

adults with incapacity guardianship order

60
Q

legal course of action for a patient reported to A&E with mania. he has no insight and attempts to leave the department. on call psych is held up.

A

section 36- emergency detention.

this can be done with a doctor who is fully registered by GMC (FY2 up?)

61
Q

legal course of action for a man withy severe depression who is detained under short term detention. he still has no insight but doesnt think he need more ECT as he thinks he will die under the anaesthetic. the psych doctor still thinks he needs more ECT.

A

certificate of the designated medical practioner

62
Q

change from one mature cell type to another

A

metaplasia

63
Q

increase in number of cells

A

hyperplasia

64
Q

abnormal cell proliferation

65
Q

how to treat MODY?

A

sulphonylurea- glicizide

66
Q

30 year old man with change in personality, peripheral neuropathy, atxia and tremor. eye doctors notices somethin interesting

A

wilsons disease

67
Q

42 year old man presents with abnormal movements in his limbs that he cant control. his dad died young with similar issues

A

huntingsons

68
Q

80 year old man with tremor, visual hallucination and decline in cogntion with falls. these symptoms fluctuate

A

lewy body dementia

69
Q

6 month old baby. funny breathing and cough for last 2 days. subcostal recession and widespread wheeze. big bro had runny nose recently

A

bronchiolitis

70
Q

2 day old infant started vomiting. non projectile, mild and green colour.

A

volvulus.

bile coloured vomit is always abnormal. do plain AXR first line

71
Q

2 week old infant born at term started vomiting at day 4 of age. infant has been breastfed . vomiting is projectile and associated with constipation. they appear well and eager to feed

A

pyloric stenosis

-classical projectile vomit and hungry child

72
Q

3 week old infant born at term. started vomting on day 7. vomit is of small amount and is effortless. and almmost after every feed. appears well and is gaining weight

73
Q

perecentage of children that will have height within 2 standard deviations of the mena

74
Q

the age in months that it is recommended that a childs height should be measured rather than length

A

24 months ( 2 years)

75
Q

ST elevation in V2-5

A

anterior MI

76
Q

ST elevation in V1-3

A

anteroseptal

77
Q

ST elevation in V4-6, aVL, I

A

anterolateral

78
Q

ST elevation in II, III, aVF

79
Q

ST elevation iN V1-2 (reciprocal)

A

posterior MI

80
Q

is this a true adpation to pregnancy?

A

BP decreases in second trimester and returns to pre-preg levels by 3rd trimester

81
Q

45 year old female with red hot swolleb joints symmetrically in hands and feet . inflam markers are raised

A

this is rheumatoid- check anti-ccp

82
Q

middle aged woman, complains of fingers turning blue int he cold as well as bad heart burn. echo shows increased pulmonary artery pressure.

A

check anti-centromere

this is limited systemic slcerosis

83
Q

first line for C diff

A

oral metronidazol

84
Q

23 year old as abdo cramps and diarrhoea following a BBQ. vital signs are fine. temp 38. campylobacter is isolated in the stool… do you trear

A

in an otherwise fit person, the treatment is supportive

85
Q

45 year old travelller from pakistan presents with abdo pain and loose stools and fever, faint rash over abdo and chest. temp of 40 degrees, ,he is hypotensive and tachycardic. blood cultures are posiitve for gram neg rod and typhoid seems likely diagnosis,

A

this is salmonella typhi. usually resistant to ciprolfoxacin so give IV ceftriaxone

86
Q

60 year old man complains on 6 week history of sore throat and haorse voice. what is this likely to be?

A

laryngopharyngeal reflux

87
Q

preffered measure of central tendency in a normally distributed data set

88
Q

a measurement of how spread out data values are

A

standard deviation

measures the degree to which individuals differ from the sample mean

89
Q

a level of variable which is exceeded by 10% of the population

A

90th centile

90
Q

foul smelling discharge and microspopy shows flagellated protozoa

A

trichomonas vaginalis

91
Q

30 year old man presents to GP with painful red eye for a few days. he also complains of right knee piain and stinging on peeing. which test may identify the cause?

A

urine PCR

this is chlamydia

92
Q

50 year old man with fever, cough and right sided chest pain. CXR shows right sided consolidation. blood cultures are positive. likely bug?

A

this is strep. pneumoniae

gram positive diplocccci

93
Q

is the surgeons knot more secure than a reef knot?

94
Q

elderly lady with peripheral vascular disease presents with PR bleed. abdo pain and high lactate.

A

ischaemic bowel

common in old folk with known vascular disease

95
Q

30 year old female, abdo pain, weight loss, change in bowel habit and itcy rash on elbow

A

coeliac

associated with dermaitits herpetiformis

96
Q

24 year old male operning his bowels 10 times a day with blood and mucous, he has lost weight and has mouth ulcers

97
Q

does pheytoin reduce efficacy of the pill

98
Q

complication of thyroidectomy due to damaging the laryngeal nerve?

A

hoarse voice

99
Q

75 year old man with COPD, IHD and hypertension has a painful ulcer on top of right foot. ABPI’s are 0.76 (L) and 0.68(R) which are reduced.

what type opf ulcer?

100
Q

85 year old woman with undiagnosed connective tissue disease has many superficial ulcers over both lower legs from knee down. pupura is evident onn intact skin

A

vascualitis

101
Q

82 year old lady with ulcers on both malleoli of left leg and lipodermatsclerosis of surrounding skin. ABPI left is 1.13 and 0.96 on right.

what type of ucler