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CCS drug bank > Year 3 drug bank > Flashcards

Year 3 drug bank Flashcards

1
Q

Amitriptyline

Drug type:

Indications:

Main side effects:

Notes:

A

Drug type: Tricyclic antidepressant

Indications:

  • major depressive disorder
  • neuropathic pain
  • prophylaxis for chronic pain
  • tension headaches
  • migraine

Main side effects:

  • drowsiness
  • dry mouth
  • blurred vision
  • constipation
  • urinary retention
  • lengthening of QT interval

Notes: amitripyline are most dangerous in overdose, lofepramine is less

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2
Q

Amlodipine

Drug type:

Indications:

Side effects:

Notes:

A

Drug type: Dihydropridine clacium channel blocker

Indications:

  • angina prevention
  • hypertension
  • Raynaud’s

Side effects:

  • Flushing
  • headache
  • ankle swelling

Notes:

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3
Q

Apixaban

Drug type:

Indications:

Side effects:

Notes:

A

Drug type: DOAC- highly specific direct factor Xa inhibitor

Indications:

  • reduce the risk of stroke and systemic embolism
  • prophylaxis for DVT –> PE following hip or knee surgery

Side effects:

  • anaemia
  • haemorrhage
  • nausea
  • skin reaction

Notes:

reversal via andexanet

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4
Q

Aripiprazole

Drug type:

Indications:

Side effects:

A

Drug type: atypical antipsychotic–> D2 partial agonist with weak 5HTLa partial agonism

Indications:

  • Schizophrenia
  • Mania
  • Major depressive disorder

Side effects:

  • weight gain
  • hyperprolactinaemia
  • increased risk of stroke and venous thromboembolism in elderly patients
  • galactorrhoea
  • gynaecomastia
  • hypotension
  • leucopaenia
  • muscle rigidity, parkinsonism
  • QT prolongation
  • tremor

Notes: atypical antispychotics are now first line treatment for schiuzophrenia due to less extra-pyramidal side effects

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5
Q

Aspirin

Drug class

Indication

Side effects

Notes

A

Drug class: NSAID antiplatelet

Indication:

  • Unstable angina
  • NSTEMI
  • STEMI
  • TIA
  • Ischaemic stroke
  • AF

Side effects:

  • Dyspepsia (so prescirbe PPI)
  • haemorrhage

Notes: works by blocking cyclooxygenase-1 and 2. COX produces prostaglandin, prostacyclin and thromboxane. Blocking thromboxane A2 stops platelet aggregation.

300mg in acute heart attacks.

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6
Q

Atenolol

Drug class:

Indication

Side effects

Contraindications

A

Drug class: beta blocker- beta 1 selective blocker

Indication:

  • Hypertension
  • Angina
  • Arrhythmias- rate control for AF
  • Migraine prophylaxis
  • thyrotoxicosis
  • migraine prophylaxis
  • physiological symptoms of anxiety

Side effects:

  • hypotension–> falls
  • dry eyes
  • bronchospasm–> dyspnoea
  • cold peripheries
  • fatigue
  • sleep disturbances inc. nightmares
  • erectile dysfunction
  • vomiting

Contraindications:

  • Uncontrolled HF
  • asthma
  • sick sinus syndrome
  • concurrent verapamil use –> severe bradycardia
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7
Q

Atorvastatin

Drug class

Indication

Side effects

Notes

A

Drug class: statin–> HMG-CoA reductase inhibitor

Indication;

  • dyslipidaemias (rfx for atherosclerosis) e.g., T2DM
  • prevention of MI, stroke, angina

Side effects:

  • myopathy–> myalgia, rhabdomyolysis and asymptomatic raised creatinione kinase
  • liver impairment –> check LFTs
  • nausea
  • indigestion
  • nosebleeds
  • constipation
  • diarrhoea

Notes:

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8
Q

Beclametasone

Drug class

Indication

Side effects

Notes

A

Drug class: inhaled corticosteroid

Indication:

  • prophylaxis asthma
  • allergic rhinits
  • severe inflammatory skin disorders (psoriasis)
  • oral ulceration

Side effects:

  • headache
  • oral candiasis
  • pneumonia in COPD patients

Notes

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9
Q

Bendroflumethiazide

Drug class

Indication

Side effects

Notes

A

Drug class: thiazide diuretic

Indication:

  • hypertension
  • oedema related to HF
  • supresses lactation

Side effects:

  • hypokalaemia- constipation, palpitations, fatigue, muscle weakness, spasms, tingling, numbness
  • hyponatraemia- nausea, vomiting, headache, confusion, seizures
  • hypercalcaemia
  • gout
  • impaired glucose tolerance
  • impotence

Notes: block sodium reabsorption in DCT via thiazide-sensitive Na+ CL- symporter.

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10
Q

Bisoprolol

Drug class

Indication

Side effects

Notes

A

Drug class: beta blocker

Indication:

  • Hypertension
  • Angina
  • Arrhythmias- rate control for AF
  • Migraine prophylaxis
  • thyrotoxicosis
  • migraine prophylaxis
  • physiological symptoms of anxiety

Side effects:

  • hypotension–> falls
  • dry eyes
  • bronchospasm–> dyspnoea
  • cold peripheries
  • fatigue
  • sleep disturbances inc. nightmares
  • erectile dysfunction
  • vomiting
  • Contraindications:
  • Uncontrolled HF
  • asthma
  • sick sinus syndrome
  • concurrent verapamil use –> severe bradycardia
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11
Q

Bumetanide

Drug class

Indication

Main side effects

Notes

A

Drug class: loop diuretic

Indication: oedema

Main side effects:

  • Dizziness
  • Electrolyte imbalance
  • Fatigue
  • Headache
  • Metabolic alkalosis
  • Muscle spasms
  • Nausea

Notes:

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12
Q

Candesartan/ losartan/ irbesartan

Drug class:

Indications:

Main side effects:

Notes:

A

Drug class: antihypertensive–> angiotensin II receptor blocker (AT1 receptor)

Indications:

  • hypertension
  • HF w left vent hypertrophy
  • delay progression of diabetic nephropathy
  • migraine prophylaxis

Main side effects:

  • headaches
  • dizziness
  • hyperkalaemia
  • hypotension

Notes:

  • usually used in those that can’t tolerate ACEi usually due to cough
  • use w caution in those with renal impairment
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13
Q

Carbamezapine

Drug class

Indication

Main side effects

Notes

A

Drug class: Anticonvulsant- particularly partial seizures (1st line)

Indication:

  • Seizures
  • pain from trigeminal neuralgia
  • bipolar disorder

Main side effects:

  • P450 inducer
  • dizziness and ataxia
  • drowsiness
  • visual disturbances
  • Steven-Johnson syndrome- disorder of skin and mucous membranes- flu like then painful rash and blisters killing skin
  • leucopaenia and agranulocytosis
  • hyponatraemia 2* to inappropriate ADH secretion

Notes:

  • chemically similar to tricyclic antidepressant
  • binds to Na+ channels and increases their refractory period
  • autoinduction- return of seizures after 3-4 weeks treatment
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14
Q

Carbimazole

Drug class

Indication

Main side effects

Notes

A

Drug class: imizadole antithyroid agent

Indication: treatment of

  • hyperthyroidism
  • thyrotoxicosis

Main side effects:

  • agranulocytosis
  • crosses the placenta, can be used in low doses in pregnancy
  • nausea
  • vomiting
  • diarrhoea
  • dizziness
  • headache
  • arthralgia
  • itchy skin or rash

Notes:

  • regular blood tests
  • 6 weeks high dose until euthyrotic
  • blocks thyroid peroxidase from coupling and iodinating tyrosine on thyroglobulin reducing thyroid hormone production
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15
Q

Carbocisteine

Drug class

Indication

Main side effects

Notes

A

Drug class: expectorant mucolytic

Indication

  • reduction of mucous viscosity
  • reduction of COPD and other conditions associated with increased mucous viscosity

Main side effects

  • GI haemorrhage
  • Skin reactions
  • Stevens-Johnson syndrome (rare, serious disorder of the skin and mucous membranes. Starts with flu-like symptoms  painful rash and blisters)
  • Vomiting

Notes

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16
Q

Cetrizine

  • Drug class
  • Indication
  • Side effects
  • Notes
A

Drug class: selective histamine-1 antagonist–> “non drowsy antihistamine”

Indication: symtomatic release in conditions like

  • allergic rhinitis
  • chronic urticaria
  • atopic dermatitis

Side effects:

  • sleepiness
  • dry mouth
  • feeling sick
  • dizziness
  • diarrhoea
  • weight increase

Notes:

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17
Q

Chlorphenamine

Drug class

Indication

Side effects

Notes

A

Drug class: Histamine H1 receptor antagonist

Indication:

  • rhinitis
  • urticaria
  • allergy
  • common cold
  • asthma trigger control
  • hay fever
  • vestibular disease symptoms
  • motion sickness

Side effects:

  • impaired concentration
  • dizziness
  • dry mouth
  • fatigue
  • headache
  • nausea
  • blurred vision

Notes

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18
Q

Cinnarizine

Drug class

Indication

Side effects

Notes

A

Drug class: antihistamine calcium channel blocker

Indication:

  • vertigo/ menieres
  • nausea
  • motion sickness
  • vestibnular symptoms

Side effects:

  • drowsiness
  • GI disomfort
  • nausea
  • weight increase

Notes

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19
Q

Clopidrogel

Drug class

Indication

Side effects

Notes

interactions

A

Drug class: antiplatelet (thienopyridines like ticagrelor)

Indication:

  • management of CV disease

Side effects:

  • Diarrhoea
  • GI discomfort
  • excessive bleeding
  • skin reactions

Notes: antagonist of P2Y12 adenosine diphosphate (ADP) receptor inhibiting the activation of platelets

interaction: PPI concurrent use makes clopidogrel less useful - lansoprazole ok

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20
Q

Co-beneldopa

Drug class

Indication

Side effects

Notes

A

Drug class: mixture of Levodopa (dopamine precursor) and Benserazide-peripheral decaroxylase inhibitor

Indication:

  • Parkinsons disease
  • Restless leg disease

Side effects

  • Wearing off- long term levodopa use –> wears off at end of dose –> stiff and slow
  • Dyskinesia (involuntary movements)
  • impulsive and compulsive behaviours
  • withdrawal syndrome–> sudden cessation–> depression, anxiety, pain
  • nausea
  • vomiting
  • loss of appetite
  • hallucinations
  • sleep problems

Notes

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21
Q

Co-careldopa

Drug class

Indication

Side effects

Notes

A

Drug class: mixture of carbidopa (dopa decarboxylase inhibitor) and levodopa

Indication: parkinsons disease

Side effects

  • Wearing off- happens when you have levodopa for a long time. Wears off at the end of dose stiff and slow
  • Dyskinesia (involuntary movements)
  • Impulsive and compulsive behaviours
  • Withdrawal syndrome- sudden cessation of use  depression, anxiety, pain
  • Nausea
  • Vomiting
  • Hypotension
  • Loss of appetite
  • Hallucinations
  • Sleep problems

Notes

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22
Q

Codeine sulphate:

Drug class

indication

side effects

notes

A

Drug class: opioid analgesic

indication:

  • treatment of moderate to severe pain
  • cough suppressant
  • acute diarrhoea

side effects:

  • Constipation
  • Nausea and vomiting
  • Feeling sleepy
  • Confusion, dizzy and vertigo
  • Dry mouth
  • Headaches
  • Addiction
  • Respiratory depression
  • Anaphylaxis
  • Eurphoric mood
  • Palpitations

notes

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23
Q

cyclizine

drug class

indications

side effects

notes

A

drug class:

  • anti-histamine (histamine H1 antagonist)
  • anti-emetic

indications:

prevention and treatment of:

  • nausea
  • vomiting
  • dizziness (e.g., from vertigo)

side effects:

  • drowsiness
  • blurred vision
  • dry mouth
  • headaches
  • constipation

serious:

  • muscle stiffness
  • shaking
  • severe bleeding
  • jaundice
  • anaphylaxis

notes

24
Q

Dabigatran

drug class

indications

side effects

notes

A

drug class: oral anticoagulant–> direct rhrombin inhibitor

indications:

  • prophylaxis for VTE following hip or knee surgery
  • prevention of stroke in patients w non-valvular AF who have one or more of:

previous stroke, TIA or systemic emboli

left vent ejection fraction <40%

>75 years

65+ with DM, coronary artery disease or hypertension

side effects: haemorrhage

notes:

  • reduce doses in CKD or dont prescribe if creatinine clearance <30 ml/min
  • reverse via Idarucizumab
25
Q

Diazepam

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: Benzodiazepine with

  • anticonvulsant
  • anxiolytic
  • sedative
  • muscle relaxant
  • amnesic properties

Indications:

  • panic disorders
  • severe anxiety
  • alcohol withdrawal
  • seizures

Side effects:

  • tolerance and dependance
  • withdrawal syndrome
  • insomnia
  • irritibility
  • anxiety
  • tremor
  • loss of appetite
  • tinnitus
  • perspiration
  • perceptual disturbances
  • seizures

Notes: enhance the effect of inhinitory GABA by increasing frequency of Cl- channels

26
Q

Diltiazem

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: calcium channel blocker (antihypertensive)

Indications:

  • treat hypertension
  • manage chronic stable angina

CCB Side effects:

  • ankle swelling
  • flushing
  • palpitations
  • abdo pain
  • dizziness
  • drowsiness
  • headache
  • tachycardia
  • vomiting

Specific diltiazem side effects:

  • cardiac reconstruction disorders
  • constipation
  • GI discomfort
  • Malaise

Notes:

27
Q

Doxazosin

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: alpha-1 adrenergic receptor antagonist

Indications:

  • mild to moderate hypertension
  • urinary obstruction due to benign prostatic hyperplasia

Side effects:

  • weakness
  • sleepiness
  • headaches
  • swollen feet, ankles or fingers
  • UTI or cystitis
  • stomach pain or back pain
  • nausea, indigestion or heartburn

Notes:

28
Q

Empagliflozin

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: SGLT2 inhibitor (sodium glucose co-transporter)

Indications: T2DM adjunct with diet and exercise

Side effects:

  • Thrush
  • Dysuria
  • Polyuria
  • Skin reaction

Notes:

29
Q

Enalapril

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: Prodrug of ACEi

Indications:

  • hypertension
  • CHF
  • diabetic nephropathy
  • secondary prevention of ischaemic heart disease

Side effects:

  • Dry tickly cough
  • itchy or mild rash
  • blurred vision
  • hyperkalaemia- dizziness, headaches

Notes:

  • younger patients <55?
  • less used in afro-carribbeans

Contraindications:

  • pregnancy and breastfeeding
  • renovascular disease
  • aortic stenosis
30
Q

Eplerenone

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: Antihypertensive–> Aldosterone receptor antagonist

Indications:

  • Improve survival of stable patients with left vent systolic dysfunction (EF <40%)
  • CHF after an MI

Side effects:

  • Postural hypotension
  • Headaches
  • difficulty sleeping
  • Cough

Severe:

Hyperkalaemia (muscle cramps, diarrhoea, nausea, weakness)

Notes:

Aldosterone is a minerlocorticoid steroid hormone produced by the zona glomerulosa of the adrenal gland. It acts on mineralocorticoid receptors in the DCT and nephron. Aldosterone may:

  • increase sodium reabsorption
  • increase water retention
  • increase potassium excretion
  • increase acid (H+) excretion
31
Q

Ethosuximide

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Anticonvulsant

Indication:

  • Absence seizures
  • Petit mal seizures

Side effects:

  • Upset stomach
  • Loss of appetite
  • Dairrhoea
  • Agranulocytosis
  • Impaired concentration
  • Erythema nodosum
  • Vomiting

Notes:

32
Q

Exenatide

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: GLP-1 agonist/ analogue

Indication:

As an adjunct to diet and exercise to improve glycaemic control in patients w T2DM

Side effects:

  • Decreased appetite
  • Asthenia (weakness, lack of energy or strength)
  • Constipation
  • Diarrhoea etc.

Notes: Works by activating the receptor and increasing insulin secretion, decrease glucagon and slows gastric emptying

33
Q

Ezetimibe

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Cholesterol absorption inhinitor

Indication:

  • Lower total cholesterol
  • Primary hyperlipidaemia
  • Familial cholesterolaemia

Side effects:

  • Asthenia
  • Diarrhoea
  • GI discomfort
  • GI disorders

Notes:

34
Q

Finofibrate

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Peroxisome proliferator receptor alpha activator

Indication:

  • Lowers LDL-C, total-C , triglycerides and Apo B
  • Increases HDL-C in hypercholesterolaemia and dyslipidaemia

Side effects:

  • Abdo pain
  • Diarrhoea
  • Flatulance
  • Nausea
  • Vomiting

Notes:

35
Q

Fluoxetine

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Antidepressant –> Selective serotonine reuptake inhibitor (SSRI)

Indication:

  • Major depressive disorder
  • Bulimia
  • OCD
  • Premenstrual dysphoric dusorder
  • Panic disorder
  • Bipolar 2

Side effects:

Anxiety

  • abnormal appetite
  • arthralgia
  • asthenia
  • impaired concentration
  • confusion
  • constipation
  • depersonalisation
  • diarrhoea

Notes:

Mood may worsen within first 2 weeks

36
Q

Furosemide

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Potent loop diuretic (antihypertensive?)

Indication:

  • Hypertension
  • Odema in right sided CHF
  • Liver failure
  • renal disease

Side effects:

  • Dizziness
  • Electrolyte imbalances
  • Fatigue
  • Headache
  • Metabolic alkalosis
  • Muscle spasms
  • nausea

Notes:

37
Q

Gliclazide

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Sulfonylurea

Indication: Treat hyperglycaemia in a patient w T2DM

Side effects:

  • Abdo pain
  • Diarrhoea
  • Hypoglycaemia
  • Nausea

Notes:

38
Q

Glimeripiride

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Sulfonylurea

Indication: Management of T2DM

Side effects:

  • Abdo pain
  • diarrhoea
  • hypoglycaemia (?)
  • nausea

Notes:

39
Q

Gylceryl trinitrate

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: Nitrate vasodilator

Indication: prophylaxis for angina

Side effects:

  • Arrythmias
  • asthenia
  • dizziness
  • drowsiness
  • flushing
  • headache
  • hypotension
  • nausea
  • vomiting

Notes:

40
Q

Haloperidol

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: High potency 1st generation (typical) antipsychotic

Indication:

  • Psychoses –> schizophrenia
  • Symptoms of agitation –> irritibilty, delirium

Side effects:

  • Agitation
  • amenorrhoea
  • Arrhythmias
  • constipation
  • dizziness
  • drowsiness
  • dry mouth
  • erectile dysfunction
  • gynacomastia
  • hyperglycaemia
  • hyperprolactinaemia
  • hypotension
  • insomnia
  • leucopaenia
  • movement disorders (w PD patients)
  • muscle rigidity
  • neutropaenia
  • postural hypotension
  • QT interval prolongation
  • rash
  • seizure
  • tremor
  • urinary retention
  • vomiting
  • weight gain

Notes:

41
Q

Ibuprofen

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: NSAID–> non steroidal anti-inflammatory. Non selective COX inhibitor

Indication:

  • Mild- moderate pain
  • fever inflammation

Side effects:

  • GI discomfort–> Ulcer formation
  • skin reactions
  • headaches
  • dizziness
  • nausea
  • vomiting
  • indigestion

Notes:

42
Q

Indapamide

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: thiazide diuretic

Indication:

  • hypertension
  • oedema from CHF

Side effects:

  • drowsiness
  • hyperkalaemia (muscle cramps, weakness, irregular heartbeats, severe weakness, loss of co-ordination)
  • Restless feeling
  • numbness
  • tingling
  • vomiting
  • constipation
  • headache
  • slurred speech
  • dry mouth
  • increased thirst

Notes:

43
Q

Isosorbide mononitrate

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: nitrate vasodilator

Indication: prevention of angina not treating it

Side effects:

  • arrythmias
  • asthenia
  • cerebral ischaemia
  • dizziness
  • drowsiness
  • flushing
  • headache
  • hypotension
  • nausea
  • vomiting

Notes:

44
Q

labetol

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: alpha and beta adrenergic antagonist + beta blocker

Indication:

  • hypertension
  • angina
  • sympathetic overactivity syndrome

Side effects:

  • abdo discomfort
  • bradycardia
  • confusion
  • depression
  • diarrhoea
  • dizziness
  • dry eye
  • dyspnoea
  • erectile dysfunction
  • HF
  • syncope
  • vomiting

Notes:

45
Q

lamotrigine

Drug class:

Indication:

Side effects:

Notes:

A

Drug class: phenyl triazine antiepileptic

Indication:

  • focal seizures
  • tonic-clonic seizures

Side effects:

  • Aggression
  • Agitation
  • Arthralgia
  • Diarrhoea
  • Dizziness
  • Drowsiness
  • Headache
  • Irritability
  • Nausea
  • Pain
  • Rash
  • Sleep disorders
  • Tremor
  • vomiting

Notes:

46
Q

Lansoprazole

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: proton pump inhibitor (PPI)

Indications:

  • part of H.pylori eradication (2 abxs and 1 PPI–> amoxicillin, clarithromycin and metronidazole)
  • gastro-duodenal ulcer
  • ZE-syndrome
  • GORD
  • oesophagitis
  • dyspepsia

Side effects:

  • abdo pain
  • constipation
  • diarrhoea
  • dizziness
  • dry mouth
  • GI disorders
  • headache
  • insomnia
  • nausea
  • skin reactions

Notes:

47
Q

Levitiracetam

drug class:

indication:

side effects:

notes:

A

drug class: anticonvulsant agent

indication:

  • focal seizures
  • myoclonus and tonic seizures
  • convulsive status epilepticus

side effects:

  • anxiety
  • appetite suppression
  • asthenia
  • abnormal behaviour
  • cough
  • depression
  • diarrhoea
  • dizziness
  • drowsiness
  • headache
  • increased risk of discomfort
  • insomnia
  • movement disorders
  • tremor
  • vomiting

notes:

48
Q

Levodopa

drug class:

indication:

side effects:

notes:

A

drug class: dopamine precursor

indication: parkinsons disease

side effects:

  • wearing off- happens when you have levodopa for a long time. Wears off at the end of dose stiff and slow
  • Dyskinesia (involuntary movements)
  • Impulsive and compulsive behaviours
  • Withdrawal syndrome- sudden cessation of use  depression, anxiety, pain
  • Nausea
  • Vomiting
  • Hypotension
  • Loss of appetite
  • Hallucinations
  • Sleep problems

notes:

49
Q

levopromazine

drug class:

indications:

side effects:

notes:

A

drug class: phenothiazine

indications:

  • pain in palliative care
  • restlessness and confusion in palliative care
  • schizophrenia

side effects:

  • Agitation
  • Amenorrhoea
  • Arrhythmias
  • Constipation
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Erectile dysfunction
  • Fatigue
  • Galactorrhoea
  • Gynaecomastia
  • Hyperglycaemia
  • Hyperprolactinaemia
  • Hypotension
  • Insomnia
  • Muscle rigidity
  • Neutropaenia
  • Parkinsonism
  • Postural hypotension
  • QT interval
  • Rash
  • Seizure
  • Vomiting
  • Weight increase

notes:

50
Q

Levothyroxine

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: synthetic T4 hormone

Indications:

  • primary hypothyroidism (w comorbid cardiac disease)
  • hyperthyroidism (block and replace regime) in combo with carbimazole

Side effects:

  • angina pectoris
  • anxiety
  • arrhythmias
  • arthralgia
  • diarrhoea
  • fever
  • headache

Notes:

51
Q

Lithium

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: mood stabilizer

Indications: manic episodes of bipolar

Side effects:

  • nephropathy
  • allergic reactions: hives, difficulty breathing, swelling of face, lips and tongue
  • lithium toxicity; muscle weakness, drowsiness, light headed, mood changes, blurred vision, ringing in ears, confusion, slurred speech

Notes:

52
Q

Loratadine

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: 2nd generation antihistamine

Indications: allergic rhinitis

Side effects:

  • drowsiness
  • nervousness in children

Notes:

53
Q

Lorazepam

Drug class:

Indications:

Side effects:

Notes:

A

Drug class:

  • short acting and rapidly acting benzodiazepine
  • sadative
  • anxiolytic

Indications:

  • short term use in anxiety
  • acute panic attacks
  • conscious sedative for procedures
  • status epilepticus
  • febrile convulsion

Side effects:

  • decreased alertness
  • anxiety
  • ataxia
  • confusion
  • depression
  • dizzinness
  • dysarthria
  • hypotension
  • nausea
  • withdrawal syndrome

Notes:

54
Q

Losartan

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: angiotensin receptor blocker–> antihypertensive

Indications:

  • hypertension
  • diabetic nephropathy

Side effects:

  • abdo pain
  • asthenia
  • back pain
  • cough
  • diarrhoea
  • hypotension
  • nausea
  • postural hypotension
  • renal impairment
  • vertigo
  • vomiting

Notes:

55
Q

low molecular weight heparin

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: naturally occuring anticoagulant

Indications: prophylaxis and treatment of:

  • VT
  • post op DVT
  • PE

Side effects:

  • skin warmth or discolouration
  • chest pain
  • irregular heartbeats
  • SOB
  • dizziness
  • anxiety
  • sweating
  • excessive bleeding
  • dark blue skin on hands or feet

Notes: often via injevction

56
Q

Mefnamic acid

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: NSAID

Indications: pain and inflammation in RA/ OA, post op pain

Side effects:

  • agranulocytosis
  • anaemia
  • angiodema
  • appetite decreased etc…

Notes:

57
Q

Metformin

Drug class:

Indications:

Side effects:

Notes:

A

Drug class: biguanide antihyperglycaemic to be used in conjunction w diet and exercise

Indications:

  • T2DM
  • POCS

Side effects:

  • Abdo pain
  • Appetite decreased
  • diarrhoea
  • GI disorder
  • Nausea
  • Taste altered
  • Vomiting

Notes:

  • Inhibits gluconeogenesis
  • Increases peripheral sensitivity to insulin

CCS drug bank (1 decks)

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