Year 3 drug bank Flashcards

1
Q

Amitriptyline

Drug type:

Indications:

Main side effects:

Notes:

A

Drug type: Tricyclic antidepressant

Indications:

  • major depressive disorder
  • neuropathic pain
  • prophylaxis for chronic pain
  • tension headaches
  • migraine

Main side effects:

  • drowsiness
  • dry mouth
  • blurred vision
  • constipation
  • urinary retention
  • lengthening of QT interval

Notes: amitripyline are most dangerous in overdose, lofepramine is less

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2
Q

Amlodipine

Drug type:

Indications:

Side effects:

Notes:

A

Drug type: Dihydropridine clacium channel blocker

Indications:

  • angina prevention
  • hypertension
  • Raynaud’s

Side effects:

  • Flushing
  • headache
  • ankle swelling

Notes:

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3
Q

Apixaban

Drug type:

Indications:

Side effects:

Notes:

A

Drug type: DOAC- highly specific direct factor Xa inhibitor

Indications:

  • reduce the risk of stroke and systemic embolism
  • prophylaxis for DVT –> PE following hip or knee surgery

Side effects:

  • anaemia
  • haemorrhage
  • nausea
  • skin reaction

Notes:

reversal via andexanet

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4
Q

Aripiprazole

Drug type:

Indications:

Side effects:

A

Drug type: atypical antipsychotic–> D2 partial agonist with weak 5HTLa partial agonism

Indications:

  • Schizophrenia
  • Mania
  • Major depressive disorder

Side effects:

  • weight gain
  • hyperprolactinaemia
  • increased risk of stroke and venous thromboembolism in elderly patients
  • galactorrhoea
  • gynaecomastia
  • hypotension
  • leucopaenia
  • muscle rigidity, parkinsonism
  • QT prolongation
  • tremor

Notes: atypical antispychotics are now first line treatment for schiuzophrenia due to less extra-pyramidal side effects

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5
Q

Aspirin

Drug class

Indication

Side effects

Notes

A

Drug class: NSAID antiplatelet

Indication:

  • Unstable angina
  • NSTEMI
  • STEMI
  • TIA
  • Ischaemic stroke
  • AF

Side effects:

  • Dyspepsia (so prescirbe PPI)
  • haemorrhage

Notes: works by blocking cyclooxygenase-1 and 2. COX produces prostaglandin, prostacyclin and thromboxane. Blocking thromboxane A2 stops platelet aggregation.

300mg in acute heart attacks.

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6
Q

Atenolol

Drug class:

Indication

Side effects

Contraindications

A

Drug class: beta blocker- beta 1 selective blocker

Indication:

  • Hypertension
  • Angina
  • Arrhythmias- rate control for AF
  • Migraine prophylaxis
  • thyrotoxicosis
  • migraine prophylaxis
  • physiological symptoms of anxiety

Side effects:

  • hypotension–> falls
  • dry eyes
  • bronchospasm–> dyspnoea
  • cold peripheries
  • fatigue
  • sleep disturbances inc. nightmares
  • erectile dysfunction
  • vomiting

Contraindications:

  • Uncontrolled HF
  • asthma
  • sick sinus syndrome
  • concurrent verapamil use –> severe bradycardia
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7
Q

Atorvastatin

Drug class

Indication

Side effects

Notes

A

Drug class: statin–> HMG-CoA reductase inhibitor

Indication;

  • dyslipidaemias (rfx for atherosclerosis) e.g., T2DM
  • prevention of MI, stroke, angina

Side effects:

  • myopathy–> myalgia, rhabdomyolysis and asymptomatic raised creatinione kinase
  • liver impairment –> check LFTs
  • nausea
  • indigestion
  • nosebleeds
  • constipation
  • diarrhoea

Notes:

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8
Q

Beclametasone

Drug class

Indication

Side effects

Notes

A

Drug class: inhaled corticosteroid

Indication:

  • prophylaxis asthma
  • allergic rhinits
  • severe inflammatory skin disorders (psoriasis)
  • oral ulceration

Side effects:

  • headache
  • oral candiasis
  • pneumonia in COPD patients

Notes

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9
Q

Bendroflumethiazide

Drug class

Indication

Side effects

Notes

A

Drug class: thiazide diuretic

Indication:

  • hypertension
  • oedema related to HF
  • supresses lactation

Side effects:

  • hypokalaemia- constipation, palpitations, fatigue, muscle weakness, spasms, tingling, numbness
  • hyponatraemia- nausea, vomiting, headache, confusion, seizures
  • hypercalcaemia
  • gout
  • impaired glucose tolerance
  • impotence

Notes: block sodium reabsorption in DCT via thiazide-sensitive Na+ CL- symporter.

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10
Q

Bisoprolol

Drug class

Indication

Side effects

Notes

A

Drug class: beta blocker

Indication:

  • Hypertension
  • Angina
  • Arrhythmias- rate control for AF
  • Migraine prophylaxis
  • thyrotoxicosis
  • migraine prophylaxis
  • physiological symptoms of anxiety

Side effects:

  • hypotension–> falls
  • dry eyes
  • bronchospasm–> dyspnoea
  • cold peripheries
  • fatigue
  • sleep disturbances inc. nightmares
  • erectile dysfunction
  • vomiting
  • Contraindications:
  • Uncontrolled HF
  • asthma
  • sick sinus syndrome
  • concurrent verapamil use –> severe bradycardia
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11
Q

Bumetanide

Drug class

Indication

Main side effects

Notes

A

Drug class: loop diuretic

Indication: oedema

Main side effects:

  • Dizziness
  • Electrolyte imbalance
  • Fatigue
  • Headache
  • Metabolic alkalosis
  • Muscle spasms
  • Nausea

Notes:

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12
Q

Candesartan/ losartan/ irbesartan

Drug class:

Indications:

Main side effects:

Notes:

A

Drug class: antihypertensive–> angiotensin II receptor blocker (AT1 receptor)

Indications:

  • hypertension
  • HF w left vent hypertrophy
  • delay progression of diabetic nephropathy
  • migraine prophylaxis

Main side effects:

  • headaches
  • dizziness
  • hyperkalaemia
  • hypotension

Notes:

  • usually used in those that can’t tolerate ACEi usually due to cough
  • use w caution in those with renal impairment
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13
Q

Carbamezapine

Drug class

Indication

Main side effects

Notes

A

Drug class: Anticonvulsant- particularly partial seizures (1st line)

Indication:

  • Seizures
  • pain from trigeminal neuralgia
  • bipolar disorder

Main side effects:

  • P450 inducer
  • dizziness and ataxia
  • drowsiness
  • visual disturbances
  • Steven-Johnson syndrome- disorder of skin and mucous membranes- flu like then painful rash and blisters killing skin
  • leucopaenia and agranulocytosis
  • hyponatraemia 2* to inappropriate ADH secretion

Notes:

  • chemically similar to tricyclic antidepressant
  • binds to Na+ channels and increases their refractory period
  • autoinduction- return of seizures after 3-4 weeks treatment
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14
Q

Carbimazole

Drug class

Indication

Main side effects

Notes

A

Drug class: imizadole antithyroid agent

Indication: treatment of

  • hyperthyroidism
  • thyrotoxicosis

Main side effects:

  • agranulocytosis
  • crosses the placenta, can be used in low doses in pregnancy
  • nausea
  • vomiting
  • diarrhoea
  • dizziness
  • headache
  • arthralgia
  • itchy skin or rash

Notes:

  • regular blood tests
  • 6 weeks high dose until euthyrotic
  • blocks thyroid peroxidase from coupling and iodinating tyrosine on thyroglobulin reducing thyroid hormone production
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15
Q

Carbocisteine

Drug class

Indication

Main side effects

Notes

A

Drug class: expectorant mucolytic

Indication

  • reduction of mucous viscosity
  • reduction of COPD and other conditions associated with increased mucous viscosity

Main side effects

  • GI haemorrhage
  • Skin reactions
  • Stevens-Johnson syndrome (rare, serious disorder of the skin and mucous membranes. Starts with flu-like symptoms  painful rash and blisters)
  • Vomiting

Notes

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16
Q

Cetrizine

  • Drug class
  • Indication
  • Side effects
  • Notes
A

Drug class: selective histamine-1 antagonist–> “non drowsy antihistamine”

Indication: symtomatic release in conditions like

  • allergic rhinitis
  • chronic urticaria
  • atopic dermatitis

Side effects:

  • sleepiness
  • dry mouth
  • feeling sick
  • dizziness
  • diarrhoea
  • weight increase

Notes:

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17
Q

Chlorphenamine

Drug class

Indication

Side effects

Notes

A

Drug class: Histamine H1 receptor antagonist

Indication:

  • rhinitis
  • urticaria
  • allergy
  • common cold
  • asthma trigger control
  • hay fever
  • vestibular disease symptoms
  • motion sickness

Side effects:

  • impaired concentration
  • dizziness
  • dry mouth
  • fatigue
  • headache
  • nausea
  • blurred vision

Notes

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18
Q

Cinnarizine

Drug class

Indication

Side effects

Notes

A

Drug class: antihistamine calcium channel blocker

Indication:

  • vertigo/ menieres
  • nausea
  • motion sickness
  • vestibnular symptoms

Side effects:

  • drowsiness
  • GI disomfort
  • nausea
  • weight increase

Notes

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19
Q

Clopidrogel

Drug class

Indication

Side effects

Notes

interactions

A

Drug class: antiplatelet (thienopyridines like ticagrelor)

Indication:

  • management of CV disease

Side effects:

  • Diarrhoea
  • GI discomfort
  • excessive bleeding
  • skin reactions

Notes: antagonist of P2Y12 adenosine diphosphate (ADP) receptor inhibiting the activation of platelets

interaction: PPI concurrent use makes clopidogrel less useful - lansoprazole ok

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20
Q

Co-beneldopa

Drug class

Indication

Side effects

Notes

A

Drug class: mixture of Levodopa (dopamine precursor) and Benserazide-peripheral decaroxylase inhibitor

Indication:

  • Parkinsons disease
  • Restless leg disease

Side effects

  • Wearing off- long term levodopa use –> wears off at end of dose –> stiff and slow
  • Dyskinesia (involuntary movements)
  • impulsive and compulsive behaviours
  • withdrawal syndrome–> sudden cessation–> depression, anxiety, pain
  • nausea
  • vomiting
  • loss of appetite
  • hallucinations
  • sleep problems

Notes

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21
Q

Co-careldopa

Drug class

Indication

Side effects

Notes

A

Drug class: mixture of carbidopa (dopa decarboxylase inhibitor) and levodopa

Indication: parkinsons disease

Side effects

  • Wearing off- happens when you have levodopa for a long time. Wears off at the end of dose stiff and slow
  • Dyskinesia (involuntary movements)
  • Impulsive and compulsive behaviours
  • Withdrawal syndrome- sudden cessation of use  depression, anxiety, pain
  • Nausea
  • Vomiting
  • Hypotension
  • Loss of appetite
  • Hallucinations
  • Sleep problems

Notes

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22
Q

Codeine sulphate:

Drug class

indication

side effects

notes

A

Drug class: opioid analgesic

indication:

  • treatment of moderate to severe pain
  • cough suppressant
  • acute diarrhoea

side effects:

  • Constipation
  • Nausea and vomiting
  • Feeling sleepy
  • Confusion, dizzy and vertigo
  • Dry mouth
  • Headaches
  • Addiction
  • Respiratory depression
  • Anaphylaxis
  • Eurphoric mood
  • Palpitations

notes

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23
Q

cyclizine

drug class

indications

side effects

notes

A

drug class:

  • anti-histamine (histamine H1 antagonist)
  • anti-emetic

indications:

prevention and treatment of:

  • nausea
  • vomiting
  • dizziness (e.g., from vertigo)

side effects:

  • drowsiness
  • blurred vision
  • dry mouth
  • headaches
  • constipation

serious:

  • muscle stiffness
  • shaking
  • severe bleeding
  • jaundice
  • anaphylaxis

notes

24
Q

Dabigatran

drug class

indications

side effects

notes

A

drug class: oral anticoagulant–> direct rhrombin inhibitor

indications:

  • prophylaxis for VTE following hip or knee surgery
  • prevention of stroke in patients w non-valvular AF who have one or more of:

previous stroke, TIA or systemic emboli

left vent ejection fraction <40%

>75 years

65+ with DM, coronary artery disease or hypertension

side effects: haemorrhage

notes:

  • reduce doses in CKD or dont prescribe if creatinine clearance <30 ml/min
  • reverse via Idarucizumab
25
Diazepam ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: Benzodiazepine with * anticonvulsant * anxiolytic * sedative * muscle relaxant * amnesic properties Indications: * panic disorders * severe anxiety * alcohol withdrawal * seizures Side effects: * tolerance and dependance * withdrawal syndrome * insomnia * irritibility * anxiety * tremor * loss of appetite * tinnitus * perspiration * perceptual disturbances * seizures Notes: enhance the effect of inhinitory GABA by increasing frequency of Cl- channels
26
Diltiazem ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: calcium channel blocker (antihypertensive) Indications: * treat hypertension * manage chronic stable angina CCB Side effects: * ankle swelling * flushing * palpitations * abdo pain * dizziness * drowsiness * headache * tachycardia * vomiting Specific diltiazem side effects: * cardiac reconstruction disorders * constipation * GI discomfort * Malaise Notes:
27
Doxazosin ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: alpha-1 adrenergic receptor antagonist Indications: * mild to moderate hypertension * urinary obstruction due to benign prostatic hyperplasia Side effects: * weakness * sleepiness * headaches * swollen feet, ankles or fingers * UTI or cystitis * stomach pain or back pain * nausea, indigestion or heartburn Notes:
28
***_Empagliflozin_*** ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: SGLT2 inhibitor (sodium glucose co-transporter) Indications: T2DM adjunct with diet and exercise Side effects: * Thrush * Dysuria * Polyuria * Skin reaction Notes:
29
Enalapril ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: Prodrug of ACEi Indications: * hypertension * CHF * diabetic nephropathy * secondary prevention of ischaemic heart disease Side effects: * Dry tickly cough * itchy or mild rash * blurred vision * hyperkalaemia- dizziness, headaches Notes: * younger patients \<55? * less used in afro-carribbeans Contraindications: * pregnancy and breastfeeding * renovascular disease * aortic stenosis
30
Eplerenone ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: Antihypertensive--\> Aldosterone receptor antagonist Indications: * Improve survival of stable patients with left vent systolic dysfunction (EF \<40%) * CHF after an MI Side effects: * Postural hypotension * Headaches * difficulty sleeping * Cough Severe: Hyperkalaemia (muscle cramps, diarrhoea, nausea, weakness) Notes: Aldosterone is a minerlocorticoid steroid hormone produced by the zona glomerulosa of the adrenal gland. It acts on mineralocorticoid receptors in the DCT and nephron. Aldosterone may: * increase sodium reabsorption * increase water retention * increase potassium excretion * increase acid (H+) excretion
31
Ethosuximide ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Anticonvulsant Indication: * Absence seizures * Petit mal seizures Side effects: * Upset stomach * Loss of appetite * Dairrhoea * Agranulocytosis * Impaired concentration * Erythema nodosum * Vomiting Notes:
32
Exenatide ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: GLP-1 agonist/ analogue Indication: As an adjunct to diet and exercise to improve glycaemic control in patients w T2DM Side effects: * Decreased appetite * Asthenia (weakness, lack of energy or strength) * Constipation * Diarrhoea etc. Notes: Works by activating the receptor and increasing insulin secretion, decrease glucagon and slows gastric emptying
33
Ezetimibe ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Cholesterol absorption inhinitor Indication: * Lower total cholesterol * Primary hyperlipidaemia * Familial cholesterolaemia Side effects: * Asthenia * Diarrhoea * GI discomfort * GI disorders Notes:
34
Finofibrate ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Peroxisome proliferator receptor alpha activator Indication: * Lowers LDL-C, total-C , triglycerides and Apo B * Increases HDL-C in hypercholesterolaemia and dyslipidaemia Side effects: * Abdo pain * Diarrhoea * Flatulance * Nausea * Vomiting Notes:
35
Fluoxetine ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Antidepressant --\> Selective serotonine reuptake inhibitor (SSRI) Indication: * Major depressive disorder * Bulimia * OCD * Premenstrual dysphoric dusorder * Panic disorder * Bipolar 2 Side effects: Anxiety * abnormal appetite * arthralgia * asthenia * impaired concentration * confusion * constipation * depersonalisation * diarrhoea Notes: Mood may worsen within first 2 weeks
36
Furosemide ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Potent loop diuretic (antihypertensive?) Indication: * Hypertension * Odema in right sided CHF * Liver failure * renal disease Side effects: * Dizziness * Electrolyte imbalances * Fatigue * Headache * Metabolic alkalosis * Muscle spasms * nausea Notes:
37
Gliclazide ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Sulfonylurea Indication: Treat hyperglycaemia in a patient w T2DM Side effects: * Abdo pain * Diarrhoea * Hypoglycaemia * Nausea Notes:
38
Glimeripiride ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Sulfonylurea Indication: Management of T2DM Side effects: * Abdo pain * diarrhoea * hypoglycaemia (?) * nausea Notes:
39
Gylceryl trinitrate ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: Nitrate vasodilator Indication: prophylaxis for angina Side effects: * Arrythmias * asthenia * dizziness * drowsiness * flushing * headache * hypotension * nausea * vomiting Notes:
40
Haloperidol ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: High potency 1st generation (typical) antipsychotic Indication: * Psychoses --\> schizophrenia * Symptoms of agitation --\> irritibilty, delirium Side effects: * Agitation * amenorrhoea * Arrhythmias * constipation * dizziness * drowsiness * dry mouth * erectile dysfunction * gynacomastia * hyperglycaemia * hyperprolactinaemia * hypotension * insomnia * leucopaenia * movement disorders (w PD patients) * muscle rigidity * neutropaenia * postural hypotension * QT interval prolongation * rash * seizure * tremor * urinary retention * vomiting * weight gain Notes:
41
Ibuprofen ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: NSAID--\> non steroidal anti-inflammatory. Non selective COX inhibitor Indication: * Mild- moderate pain * fever inflammation Side effects: * GI discomfort--\> Ulcer formation * skin reactions * headaches * dizziness * nausea * vomiting * indigestion Notes:
42
Indapamide ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: thiazide diuretic Indication: * hypertension * oedema from CHF Side effects: * drowsiness * hyperkalaemia (muscle cramps, weakness, irregular heartbeats, severe weakness, loss of co-ordination) * Restless feeling * numbness * tingling * vomiting * constipation * headache * slurred speech * dry mouth * increased thirst Notes:
43
Isosorbide mononitrate ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: nitrate vasodilator Indication: prevention of angina not treating it Side effects: * arrythmias * asthenia * cerebral ischaemia * dizziness * drowsiness * flushing * headache * hypotension * nausea * vomiting Notes:
44
labetol ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: alpha and beta adrenergic antagonist + beta blocker Indication: * hypertension * angina * sympathetic overactivity syndrome Side effects: * abdo discomfort * bradycardia * confusion * depression * diarrhoea * dizziness * dry eye * dyspnoea * erectile dysfunction * HF * syncope * vomiting Notes:
45
lamotrigine ## Footnote Drug class: Indication: Side effects: Notes:
Drug class: phenyl triazine antiepileptic Indication: * focal seizures * tonic-clonic seizures Side effects: * Aggression * Agitation * Arthralgia * Diarrhoea * Dizziness * Drowsiness * Headache * Irritability * Nausea * Pain * Rash * Sleep disorders * Tremor * vomiting Notes:
46
Lansoprazole ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: proton pump inhibitor (PPI) Indications: * part of H.pylori eradication (2 abxs and 1 PPI--\> amoxicillin, clarithromycin and metronidazole) * gastro-duodenal ulcer * ZE-syndrome * GORD * oesophagitis * dyspepsia Side effects: * abdo pain * constipation * diarrhoea * dizziness * dry mouth * GI disorders * headache * insomnia * nausea * skin reactions Notes:
47
Levitiracetam ## Footnote drug class: indication: side effects: notes:
drug class: anticonvulsant agent indication: * focal seizures * myoclonus and tonic seizures * convulsive status epilepticus side effects: * anxiety * appetite suppression * asthenia * abnormal behaviour * cough * depression * diarrhoea * dizziness * drowsiness * headache * increased risk of discomfort * insomnia * movement disorders * tremor * vomiting notes:
48
Levodopa ## Footnote drug class: indication: side effects: notes:
drug class: dopamine precursor indication: parkinsons disease side effects: * wearing off- happens when you have levodopa for a long time. Wears off at the end of dose stiff and slow * Dyskinesia (involuntary movements) * Impulsive and compulsive behaviours * Withdrawal syndrome- sudden cessation of use  depression, anxiety, pain * Nausea * Vomiting * Hypotension * Loss of appetite * Hallucinations * Sleep problems notes:
49
levopromazine ## Footnote drug class: indications: side effects: notes:
drug class: phenothiazine indications: * pain in palliative care * restlessness and confusion in palliative care * schizophrenia side effects: * Agitation * Amenorrhoea * Arrhythmias * Constipation * Dizziness * Drowsiness * Dry mouth * Erectile dysfunction * Fatigue * Galactorrhoea * Gynaecomastia * Hyperglycaemia * Hyperprolactinaemia * Hypotension * Insomnia * Muscle rigidity * Neutropaenia * Parkinsonism * Postural hypotension * QT interval * Rash * Seizure * Vomiting * Weight increase notes:
50
Levothyroxine ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: synthetic T4 hormone Indications: * primary hypothyroidism (w comorbid cardiac disease) * hyperthyroidism (block and replace regime) in combo with carbimazole Side effects: * angina pectoris * anxiety * arrhythmias * arthralgia * diarrhoea * fever * headache Notes:
51
Lithium ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: mood stabilizer Indications: manic episodes of bipolar Side effects: * nephropathy * allergic reactions: hives, difficulty breathing, swelling of face, lips and tongue * **lithium toxicity;** muscle weakness, drowsiness, light headed, mood changes, blurred vision, ringing in ears, confusion, slurred speech Notes:
52
Loratadine ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: 2nd generation antihistamine Indications: allergic rhinitis Side effects: * drowsiness * nervousness in children Notes:
53
Lorazepam ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: * short acting and rapidly acting benzodiazepine * sadative * anxiolytic Indications: * short term use in anxiety * acute panic attacks * conscious sedative for procedures * status epilepticus * febrile convulsion Side effects: * decreased alertness * anxiety * ataxia * confusion * depression * dizzinness * dysarthria * hypotension * nausea * withdrawal syndrome Notes:
54
Losartan ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: angiotensin receptor blocker--\> antihypertensive Indications: * hypertension * diabetic nephropathy Side effects: * abdo pain * asthenia * back pain * cough * diarrhoea * hypotension * nausea * postural hypotension * renal impairment * vertigo * vomiting Notes:
55
low molecular weight heparin ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: naturally occuring anticoagulant Indications: prophylaxis and treatment of: * VT * post op DVT * PE Side effects: * skin warmth or discolouration * chest pain * irregular heartbeats * SOB * dizziness * anxiety * sweating * excessive bleeding * dark blue skin on hands or feet Notes: often via injevction
56
Mefnamic acid ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: NSAID Indications: pain and inflammation in RA/ OA, post op pain Side effects: * agranulocytosis * anaemia * angiodema * appetite decreased etc... Notes:
57
Metformin ## Footnote Drug class: Indications: Side effects: Notes:
Drug class: biguanide antihyperglycaemic to be used in conjunction w diet and exercise Indications: * T2DM * POCS Side effects: * Abdo pain * Appetite decreased * diarrhoea * GI disorder * Nausea * Taste altered * Vomiting Notes: * Inhibits gluconeogenesis * Increases peripheral sensitivity to insulin