Y3 Anaesthetics Flashcards
What is pain?
pain is the unpleasant sensory and emotional experience associated with actual or potential tissue damage
What are the 3 durations of pain?
acute, chronic and acute on chronic
What are the two broad causes for pain?
Cancer and non-cancer
What are the 2 pathway mechanisms of pain?
nociceptive and neuropathic
What is acute pain described as?
pain of recent onset and probable limited duration
What is chronic pain defined as?
pain lasting more than 3 months, pain lasting after normal healing, often no identifiable cause
What is cancer pain defined as a?
Progressive, may be a mixture of acute and chronic
Nociceptive pain is caused by what happening?
Obvious tissue injury or illness
Is nociceptive pain sharp/dull and well/poorly localised?
Can be sharp or dull and is well localised
What causes Neuropathic pain?
Nervous system damage or abnormality.
What is often used to describe neuropathic pain and is it well/not well localised?
burning, shooting +/- numbness, pins and needles
not well localised
What occurs in the periphery that causes pain?
Tissue injury
release of chemical e.g. prostaglandins, substance P
Stimulation of pain receptors (nociceptors)
What nerves does pain travel in?
Ad or C nerve fibres
Where do these pain fibres enter the spinal cord?
The dorsal horn
What side of the spinal cord does the second nerve travel up?
the opposite side
What is the second relay station for the pain?
the Thalamus
Where does pain perception occur in the brain?
Occurs in the cortex
What is modulation and does it increase/ decrease pain signal?
A descending pathway from brain to dorsal horn. Usually decreases pain signal
What are some examples of neuropathic pain?
nerve trauma, diabetic pain, fibromyalgia, chronic tension headache
What are some of the simple analgesics?
Paracetamol, non steroidal anti inflammatory- NSAIDs- diclofenac, ibuprofen
What are some opioids?
Mild- codeine, dihydrocodeine
Strong- morphine, oxycodone, fentanyl
What type of treatment would be used to deal with the peripheral injury?
Non-drug treatments= RICE
NSAIDs, local anaesthetics
What kind of tx would you use to treat the spinal cord?
non drug: acupuncture, massage, TENS
local anaesthetic, opioids, ketamine
Treatments for the brain?
non drug tx: psychological
drug tx: paracetamol, opioids, amitriptyline, clondine
What are the advantages of paracetamol?
advantages- cheap, safe, can be given orally, rectally or IV.
What are the disadvantages of paracetamol?
liver damage in overdose