Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

medical biochem vitamins > xVitamin chart > Flashcards

xVitamin chart Flashcards

You may prefer our related Brainscape-certified flashcards:
USMLE® Step 1 flashcards
1
Q

thiamine-cofactor

A

TPP (thiamine phosphate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

thiamine-disease

A

beriberi/wernicke-kosakoff

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

thiamine-vitamin #

A

B1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

thiamine-typical reaction

A

decarboxylase of alpha keto-acids aldehyde transfer, transketolase
(pyruvate –> Acetyl CoA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Riboflavin-Vitamin#

A

B2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Riboflavin-cofactor

A

FAD/FMN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Riboflavin-disease

A

Deficiency rare in US chronic Alcoholics- glossitis, sebborrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Riboflavin_typical reaction

A

oxidation reduction

succinate–>fumarate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pyridoxine-vitamin #

A

B6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pyridoxine-cofactor

A

PLP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pyridoxine-disease

A

deficiency rare-

peripheral neuropathy, microcytic anemia - delta ALA synth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Pyridoxine-typical reaction

A

group transfer:
glycogen phosphorylase transaminations
Glutamate–>ketoglutarate
(aa catabolism/synth)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Nicotinic Acid-A.K.A.

A

Niacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Nicotinic Acid-vitamin #

A

B3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Nicotinic Acid-cofactor

A

NAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Nicotinic Acid-disease

A

pellagra(3D’s)

diarrhea,dermatitis,dementia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Nicotinic Acid-typical rxn

A

oxidation-reduction

malate–>OAA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Biotin-vitamin #

A

B7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Biotin-cofactor

A

Biotin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Biotin-disease

A

Dermatitis, enteritis

raw egg white consumption

21
Q

Biotin-typical rxn

A

Carboxylation-
pyruvate–>OAA
Acetyl CoA–>malonyl CoA

22
Q

Vitamin C-A.K.A

A

ASCORBIC ACID

23
Q

Vitamin C-cofactor

A

ASCORBIC ACID

24
Q

Vitamin C-disease

A

Scurvy-easily bruised, poor wound healing, hemmorrhaging

25
Q

Vitamin C-tyipical rxn

A

Hydroxylation of proline and lysine in collagen
or Dopamine Hydroxylase
Pro–>4hydroxy-Pro
or Dopamine–>NE

26
Q

Vitamin D-cofactor

A

calcitrol

27
Q

Vitamin D-disease

A

Rickets-osteomalacia:

inadequate bone mineralization

28
Q

Vitamin D-typical rxn

A

COntrols serum Ca 2+ w/ parathyroid hormone & calcitonin

Acts like steroid causing change in gene transcription

29
Q

Cu 2+: cofactor

A

Cu 2+

30
Q

Cu 2+:disease

A

menkes-deficiency

31
Q

Cu 2+:disease

A

Wilson- copper accumulation

32
Q

Cu 2+:typical rxn

A

Electron transport, lsyl oxidation

O2–> H20

33
Q

Iron: Cofactor

A

Fe2+

34
Q

Iron: disease

A

Microcytic anemia

(heme synth dependent on iron

35
Q

Iodine:cofactor

A

I+

iodinium required T3/T4

36
Q

Iodine:disease

A

associated with both:
hyperthyroid (graves disease)-BUGGED OUT EYES
hypothyroid

37
Q

Iodine:typical rxn

A

only used to make Thryoid Hormone

Tgb w/ Tyr residue + I+ –>Tgb w/T4

38
Q

Folic Acid:vitamin #`

A

B9

39
Q

Folic Acid:cofactor

A

Tetrahydrofolate-THF

40
Q

Folic Acid:disease

A

macrocytic megaloblastic anemia
spina bifida
(neurological symptoms rare)

41
Q

Folic Acid:typical rxn

A

deoxyuridylate–>Thymidylate

nucleotide biosynth

42
Q

Cobalamin:vitamin #

A

B12

43
Q

Cobalamin:cofactor

A

5’ DEoxyadenosyl cobalmin

44
Q

Cobalamin:disease

A

macrocytic megaloblastic anemia
neuropathy
(pernicious anemia=deficient in intrinsic factor)

45
Q

Cobalamin:typical rxn

A 
methyl transfer
intramolecular rearrangement 
2 relevant rxns in humans
methylmalonyl CoA-->Succinyl CoA
homocysteine + N-methyl THF--> Met + THF`
46
Q

Vitamin K:cofactor

A

Vitamin KH2

47
Q

Vitamin K:disease

A

hemmorrhagic syndrome=longer clotting times

48
Q

Vitamin K:typical rxn

A

carboxylation

Glu–>gama CarboxyGlu (gla)

medical biochem vitamins (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions