Xanthines Flashcards
1
Q
Xanthines Proposed Theories
A
- Smooth muscle relaxation via inhibition of phosphodiesterase?->leading to increase intracellular cAMP
- Antagonism of Adenosine?
- Catecholamine Release
2
Q
Theophylline Serum Levels for COPD
A
COPD: 5-10 mcg/ml
3
Q
Theophylline Serum Levels for Asthma
A
Asthma: 5-15 mcg/mL
4
Q
Theophylline Serum Levels: No Effects Seen
A
No Effects Seen: less than 5mcg/mL
5
Q
Theophylline Serum Levels: Therapeutic Range
A
Therapeutic Range: 10-20 mcg/mL
6
Q
Theophylline Serum Levels: Nausea
A
Nausea: greater than 20 mcg/mL
7
Q
Theophylline Serum Levels: Cardiac Arrhythmias
A
Cardiac Arrhythmias: greater than 30 mcg/mL
8
Q
Theophylline Serum Levels: Seizures
A
Seizures: 40-45 mcg/mL
