X-linked Dominant Inheritance with Male Lethality

Question 1

X-linked dominant traits witg male lethality:

Answer 1

incontinentia pigmenti (NEMO gene)

Rett syndrome (MECP2 gene)

X - linked periventricular heterotopia (FLNA gene)

focal dermal hypoplasia

Question 2

T/F. For an X-linked dominant trait, the birth of an affected child to unaffected parents is most likely to be due to a new mutation w/ a resulting low risk of recurrence for the couple ’ s future offspring.

Answer 2

True.