Wurpel Drugs Flashcards
What is Pseudoephedrine?
An alpha-1 agonist.
What is phenylephrine?
An alpha-1 agonist.
What is nephazoline?
An alpha-1 agonist.
What is oxymetazoline?
An alpha-1 agonist.
What is xylometazoline?
An alpha-1 agonist.
What is propylhexidrine?
An alpha-1 agonist.
What is tetrahydrozoline?
An alpha-1 agonist.
Which drugs are Alpha-1 agonists?
Pseudoephedrine, phenylephrine, nephazoline, oxymetazoline, xylometazoline, propylhexidrine, tetrahydrozoline.
What are side effects of alpha-1 agonists?
NVD, restlessness, headache, reflex bradycardia, tachycardia, palpitations.
Jittery, jumpy, restless.
Which drugs are mucoactive?
Guaifenensin & N-acetylcysteine
What does Guaifenesin do?
Stimulates secretion and reduces viscosity
What does N-acetrlcysteine do?
Cleaves disulfide bonds linking mucin polymers
What does Benzonatate do?
Anesthetizes lung & pleural tissues responsible for the cough reflex.
“Numbs” the stretch sensors in the lungs. Stretch of these sensors during breathing causes cough.
What does Benzonatate do?
Local anesthetic action.
Anesthetizes lung & pleural tissues responsible for the cough reflex.
“Numbs” the stretch sensors in the lungs. Stretch of these sensors during breathing causes cough.
What does tetracaine do?
Local cough suppression, local anesthetic.
What is special about Codeine?
Rare polymorphis @ CYP2D6 which increases morphine conc.
What is special about Dextromethorphan?
High abuse potential.
MU opioid agonist (central antitussive)
Great drug to use in combo with other abusive drugs.
