Wurpel Drugs Flashcards

1
Q

What is Pseudoephedrine?

A

An alpha-1 agonist.

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2
Q

What is phenylephrine?

A

An alpha-1 agonist.

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3
Q

What is nephazoline?

A

An alpha-1 agonist.

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4
Q

What is oxymetazoline?

A

An alpha-1 agonist.

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5
Q

What is xylometazoline?

A

An alpha-1 agonist.

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6
Q

What is propylhexidrine?

A

An alpha-1 agonist.

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7
Q

What is tetrahydrozoline?

A

An alpha-1 agonist.

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8
Q

Which drugs are Alpha-1 agonists?

A

Pseudoephedrine, phenylephrine, nephazoline, oxymetazoline, xylometazoline, propylhexidrine, tetrahydrozoline.

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9
Q

What are side effects of alpha-1 agonists?

A

NVD, restlessness, headache, reflex bradycardia, tachycardia, palpitations.

Jittery, jumpy, restless.

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10
Q

Which drugs are mucoactive?

A

Guaifenensin & N-acetylcysteine

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11
Q

What does Guaifenesin do?

A

Stimulates secretion and reduces viscosity

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12
Q

What does N-acetrlcysteine do?

A

Cleaves disulfide bonds linking mucin polymers

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13
Q

What does Benzonatate do?

A

Anesthetizes lung & pleural tissues responsible for the cough reflex.

“Numbs” the stretch sensors in the lungs. Stretch of these sensors during breathing causes cough.

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14
Q

What does Benzonatate do?

A

Local anesthetic action.

Anesthetizes lung & pleural tissues responsible for the cough reflex.

“Numbs” the stretch sensors in the lungs. Stretch of these sensors during breathing causes cough.

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15
Q

What does tetracaine do?

A

Local cough suppression, local anesthetic.

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16
Q

What is special about Codeine?

A

Rare polymorphis @ CYP2D6 which increases morphine conc.

17
Q

What is special about Dextromethorphan?

A

High abuse potential.

MU opioid agonist (central antitussive)

Great drug to use in combo with other abusive drugs.