Wrong stuff Flashcards

1
Q

A 13 year old girl in the Paediatric Emergency Department has drowsiness, weight loss and tiredness over the last 10 days. Her capillary blood gas results on arrival shows:
pH 7.01 (7.35 - 7.45)
PCO2 2.9 kPa (4.6 - 6.4)
HCO3 9 mmol/L (22 - 30)
Glucose 24 mmol/L (3.0 - 6.0)
Blood ketones 6 mmol/L

Following an initial ABC assessment, bloods were taken. Her latest observations are: temperature 37C, pulse rate 118 bpm, BP 105/74 mmHg, capillary refill time 3 seconds, respiratory rate 27 breaths per minute, oxygen saturation 96% breathing air.

Rank the following subsequent management steps in order of priority with (1) being performed first and (5) being performed last
SC insulin
Repeat blood gas
Administer a fluid bolus
IV insulin
Calculate IV fluid requirement

A

Administer a fluid bolus 1
Calculate IV fluid requirement 2
IV insulin 3
Repeat blood gas 4
SC insulin 5

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2
Q
  1. A previously well, fully immunised, 2 year old girl, has a fever, irritability and vomiting for the last 3 days. A lumbar puncture is performed, and her CSF results are as follows:
    CSF protein 0.8 g/L (0.15 - 0.45)
    Glucose 0.9 mmol/L (2.2 - 2.4) (blood glucose 7 mmol/L)
    Polymorphonuclear cells 95%
    Mononuclear cells 5%

Rank the following causative organisms in order of likelihood with (1) being the most likely and (5) being the least likely.
Streptococcus pneumoniae
Cryptococcus
Haemophilus influenzae type B
Staphylococcus aureus
Enterovirus

A

Streptococcus pneumoniae 1
Haemophilus influenzae type B 2
Staphylococcus aureus 3
Cryptococcus 4
Enterovirus 5

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3
Q

A 2 week old baby has been recently diagnosed with trisomy 21. Rank the following cardiac defects in order of likelihood
ASD
Pulmonary atresia
Mild coarctation of the aorta
AVSD
VSD

A

AVSD 1
VSD 2
ASD 3
Mild coarctation of the aorta 4
Pulmonary atresia 5

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4
Q

A 21 year old woman in the Emergency Department states that she is going to kill herself because the voices in her head are telling her to do so. Her feelings reportedly intensified following an argument with her mother earlier in the day. She demands to be admitted to the mental health unit, saying ‘it will all be your fault when I commit suicide”. She has a history of cutting and is well known to mental health services from previous crisis presentations.

Rank the following differential diagnoses in order of likelihood, with (1) being the most likely and (5) being the least likely.
Dissocial personality disorder
Paranoid schizophrenia
Depressive episode of moderate severity
Severe depressive episode with psychotic features
Emotionally unstable personality disorder

A

Severe depressive episode with psychotic features 1
Emotionally unstable personality disorder 2
Depressive episode of moderate severity 3
Paranoid schizophrenia 4
Dissocial personality disorder 5

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5
Q

A 37 year old woman in the Emergency Department has low mood, insomnia, an inability to concentrate and hopelessness for the past 6 weeks. She recently lost her job as a corporate lawyer. She had an episode of depression at the age of 26 years, which was treated with fluoxetine for 6 months. She reports being a social drinker (average consumption is 2 glasses of wine per week).

Rank the following risk factors for depression in order of significance for this woman, with (1) being the most significant and (5) being the least significant.
Alcohol intake
Gender
Age
Previous depressive episode
Recent unemployment

A

Recent unemployment 1
Previous depressive episode 2
Gender 3
Age 4
Alcohol intake 5

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6
Q

The son of an 81 year old man in General Practice is concerned about his father. His father lives alone and has become more forgetful over the past 3 months. He has left his house without shutting the door several times and has been getting lost on the way to the shops. He has well-controlled hypertension and diet-controlled Type 2 Diabetes Mellitus.

Rank the following management steps according to the sequence in which they should be implemented with (1) being carried out first and (5) being carried out last.
Arrange joint consultation with father and son
Refer to local Memory Clinic
Perform an assessment of cognition with a cognitive assessment tool
Arrange confusion screen blood tests
Assess for acute reversible causes of confusion

A

Arrange joint consultation with father and son 1
Assess for acute reversible causes of confusion 2
Perform an assessment of cognition with a cognitive assessment tool 3
Arrange confusion screen blood tests 4
Refer to local Memory Clinic 5

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7
Q

A 24 year old woman presents with a 2 day history of worsening right-sided lower abdominal pain. She is sexually active and normally uses condoms. She has a 28 day cycle and her last period was 6 weeks ago. One day ago she had loose stools and attributed this to a bad take away. She has nausea and loss of appetite but no vomiting. Her temperature is 37.3C, pulse 96 bpm, BP 110/64 mmHg, respiratory rate 18 breaths per minute, oxygen saturation 98% breathing room air.

Urine dip: blood 1+ only
Blood test results: Hb 85 g/L (115 - 150), CRP 10 mg/L (<5)

Rank the following diagnoses in order of likelihood with (1) being the most likely and (5) being the least likely.
Appendicitis
Urinary tract infection
Pyelonephritis
Ectopic pregnancy
Ovarian cyst accident

A

Ectopic pregnancy 1
Ovarian cyst accident 2
Appendicitis 3
Urinary tract infection 5
Pyelonephritis 4

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8
Q

A 36 year old mother of three young children is not using any contraception. She had a recent unplanned pregnancy and opted for a termination. She occasionally experiences headaches and smokes five cigarettes per day. Her BMI is 30 kg/m2. She has been in a relationship for 18 months.

Rank the following contraceptive choices for this woman in order of appropriateness, with (1) being the most appropriate and (5) being the least appropriate.
Combined oral contraceptive pill
Nexplanon implant
Sterilization
Mirena IUS
Condoms

A

Mirena IUS 1
Nexplanon implant 2
Condoms 3
Combined oral contraceptive pill 4
Sterilization 5

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9
Q
  1. A heterosexual couple in their early 30s have been trying to conceive for more than 1 year without success. Neither has any children.

Rank the following potential causes of their infertility in order of likelihood with (1) being the most likely and (5) being the least likely.
Gamete defects
Male infertility
Uterine or peritoneal disorders
Tubal damage
Ovulatory disorders

A

Ovulatory disorders 1
Male infertility 2
Uterine or peritoneal disorders 3
Tubal damage 4
Gamete defects 5

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10
Q
  1. A 3 week old girl has had loose stools since day 2 of life and there are now streaks of blood in the stool. The baby examies well with normal observations, normal findings on abdominal examination, but there is dry skin on the scalp and face. Which is the most likely diagnosis?
    Coeliac disease
    Cow’s milk protein allergy
    Gastroenteritis
    Intussusception
    Lactose intolerance
A

Cow’s milk protein allergy

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11
Q

A 3 year old girl with eczema has a 2 day history of a new rash on her arms (see image). Which is the most appropriate treatment for this rash?

IV aciclovir
IV flucloxacillin
Topical clobetasone
Topical emollient
Topical fucidin

A

IV aciclovir

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12
Q

A 7 year old boy has a history of recurrent chest infections, persistent sinusitis and has been prescribed multiple courses of antibiotics. He has bibasal crepitations and a right-sided apex beat. Which is the most likely underlying diagnosis?
Agammaglobulinaemia
Cystic fibrosis
HIV
Primary ciliary dyskinesia

A

Primary ciliary dyskinesia

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13
Q

A 3 day old baby girl is not feeding well. Her temperature is 36.7C, heart rate 180 bpm, respiratory rate 66 breaths per minute. There is a systolic murmur and femoral pulses are not palpable. Which is the most likely diagnosis?
Atrial septal defect
Coarctation of the aorta
Patent ductus arteriosus
Patent foramen ovale
Ventricular septal defect

A

Coarctation of the aorta

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14
Q

A 5 year old boy in General Practice has bright red blood when opening his bowels for 1 week. He opens his bowels every 3 days. He has no past medical history and is thriving. He has a well-balanced diet and has good fluid intake. There are no safeguarding concerns. Abdominal examination is unremarkable. Rectal inspection reveals a fissure. Which is the most appropriate management?
Dietary advice
Osmotic laxative
Phosphate enema
Stimulant laxative
Toilet training

A

Osmotic laxative

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15
Q

A 7 year old boy in General Practice has a sore throat, fever and pain on swallowing for 1 day. His temperature is 38.5C, pulse rate 110 bpm, respiratory rate 24 breaths per minute, and oxygen saturation 99% breathing air. He has bilateral tonsillar enlargement with exudate and bilateral cervical lymphadenopathy. He is talking in full sentences without using accessory muscles. Which is the most appropriate management?
Admit to hospital
Continue supportive measures
Prescribe amoxicillin
Prescribe phenoxymethylpenicillin
Review in 48 hours

A

Prescribe phenoxymethylpenicillin

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16
Q

A 7 year old boy in General Practice has ongoing night time bed-wetting. He is dry during the day but has never been dry at night. His mother has tried managing his fluid intake, regular toileting and a star chart for 6 months with no success. He has no past medical history and takes no regular medication. He is doing well at school and at home. Abdominal examination is unremarkable.
Urinalysis:
Glucose - negative
Protein - negative
Ketone - negative
Blood - negative
Nitrites - negative
Leukocytes - negative
Which is the most suitable management option?
Continue star chart
Desmopressin
Enuresis alarm
Imipramine
Oxybutynin

A

Enuresis alarm

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17
Q

A 30 year old woman with type I diabetes mellitus has developed end-stage renal failure and requires dialysis. She believes that the hospital (where she is admitted) has conspired to intentionally give her diabetes. She is therefore refusing to have dialysis and is actively attempting to leave the hospital. She is able to retain the relevant information and communicate her decision to refuse dialysis, which she justifies based on her thoughts that dialysis will cause her further harm. Blood investigations: potassium 6.7 mmol/L (3.5 - 5.3), Urea 50 mmol/L (2.5 - 7.8), creatinine 1200 micromol/L (60 - 120). Which is the most appropriate next step in regards to her management?
Detain the patient under Section 5(2) of the Mental Health Act and provide emergency dialysis
Facilitate a Mental Health Act assessment
Facilitate an urgenT best interests assessment
Facilitate dialysis under common law, using sedation if required
Facilitate discharge and continue discussions with the patient in the community

A

Facilitate dialysis under common law, using sedation if required

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18
Q

A 50 year old man has been feeling low in mood and describes ‘not enjoying anything’ in recent weeks. He has difficulties concentrating at work, where his performance has been declining. He is unkempt and losing weight. He has seen his GP who initiated sertraline 100mg daily 1 month ago and referred him to the community mental health team. Which is the most appropriate next step in his management?
Add lithium
Add mirtazapine
Add olanzapine
Increase the dose of sertraline
Switch to dosulepin (a TCA)

A

Increase the dose of sertraline

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19
Q

A 25 year old woman is currently an informal inpatient on a mental health ward for management of a depressive episode. She has intent to end her life. She wants to leave the ward. She is deemed to have capacity to make a decision to leave hospital. Which is the next most appropriate step in management?
Allow her to self discharge
Detain her under the Deprivation of Liberty Safeguards
Detain her under the Mental Capacity Act
Detain her under the Section 2 of the Mental Health Act
Detain her under the Section 5(2) of the Mental Health Act

A

Detain her under the Section 5(2) of the Mental Health Act

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20
Q

A 24 year old paramedic is referred to see a psychiatrist by her GP. She reports that she has not been herself after attending a call last month when the patient ultimately died. She complains of low mood and difficulty falling asleep on most nights. Her appetite is not affected and she has not lost any weight. Blood test results including full blood count and thyroid function tests are unremarkable. Which is her most likely diagnosis?
Acute stress reaction
Adjustment disorder
Depressive episode
Generalised anxiety disorder
Post-traumatic stress disorder

A

Acute stress reaction

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21
Q
  1. A 55 year old woman in General Practice has a history of recurrent depression. She has previously had cognitive behavioural therapy and antidepressant medication. She is currently well but her work has been stressful and she is worried her depression may recur. Which is the most appropriate next management option?
    Group based CBT
    Mindfulness-based cognitive therapy
    Prescribe prophylactic SSRI
    Prescribe zopiclone
    Regular follow up with GP and screening for depression
A

Mindfulness-based cognitive therapy

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22
Q

A 24 year old woman in her first pregnancy, is in spontaneous labour on the labour ward. She is using Entonox for analgesia and has now been in the second stage for 3 hours. She has been in good descent from pushing for 2 hours. The baby is in the cephalic presentation in an occipito-anterior position, vertex below the ischial spines. The foetal heart rate has been suspicious for 30 minutes. Which is the most appropriate management in this scenario?
Caesarean section
Epidural analgesia
Episiotomy
Forceps delivery
Ventouse delivery

A

Forceps delivery

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23
Q

A 27 year old woman is seen in the antenatal clinic for a routine appointment. She has a black eye which has been covered with makeup. When asked, she does not provide a clear cause for her injury. Which is the most appropriate initial course of action.
Refer to safeguarding midwife
Refer to the Caldicott guardian
Refer to the Emergency Department
Refer to the police
Refer to women’s aid

A

Refer to safeguarding midwife

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24
Q

A 42 year old woman is 12 weeks into her third pregnancy. She would like to have screening for Trisomy 21. Which is the most sensitive screening test?
Amniocentesis
Chorionic villous sampling
Non-invasive pre-natal testing (cell free DNA)
Nuchal translucency
Quadruple test

A

Non-invasive pre-natal testing (cell free DNA)

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25
Q

A 27 year old woman in the early pregnancy unit has light vaginal bleeding, 6 weeks after her last menstrual period. Transvaginal ultrasound scan (USS) shows an intrauterine gestation sac. There was no visible yolk sac or foetal pole. Which is the recommended management?
Arrange a repeat USS in 10-14 days
Arrange a repeat USS in 48 hours
Offer management for miscarriage
Reassure and discharge
Take beta-HCG and repeat in 48 hours

A

take beta-HCG and repeat in 48 hours

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26
Q

A 38 year old woman has a total abdominal hysterectomy for dysmenorrhoea. Histology shows that there were CIN 1 changes in the cervix, which were completely excised. Which is the most appropriate follow-up?
Back to routine smear recall
Colposcopy in 6 months
No follow up required
Vault smear in 6 months
Vault smear in 12 months

A

No follow up required

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27
Q

A 22 year old woman with cystic fibrosis attends the obstetric medicine clinic for preconception counselling. Development of which obstetric complication is she at greatest risk, given her pre-existing disease?
Foetal congenital malformation
Gestational diabetes
Obstetric cholestasis
Pregnancy induced hypertension
Spontaneous miscarriage

A

Pregnancy induced hypertension

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28
Q

A 40 year old woman with uterine fibroids require the active management of the third stage of labour. At which point in labour should IM syntocinon (oxytocin) be administered?
When the anterior shoulder has been delivered
When the head has been delivered
When the neonate has been delivered
When the trunk has been delivered
When the vertex is crowning

A

When the anterior shoulder has been delivered

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29
Q

A 55 year old woman in gynaecology outpatients has a BMI of 23.5 kg/m2 and a history of stress incontinence. Pelvic floor exercises have not improved her symptoms. Which is the most appropriate next step in management?
Hysterectomy
Intra urethral bulking
Ring pessary
Surgical repair
Weight loss

A

Intra urethral bulking

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30
Q

A 19 year old woman presents with an acutely painful large swelling near the opening of the vagina. She is unable to sit and passing urine is uncomfortable. Her last menstrual period started 2 days ago. Which is the most likely diagnosis?
Bartholin’s abscess
Bartholin’s cyst
Congenital urethral cyst
Urinary tract infection
Vaginal endometriosis

A

Bartholin’s abscess

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31
Q

A 34 year old woman attends her GP for her 32 week antenatal appointment. She feels well in herself and has regular foetal movements. She has had normal scans to date and an uncomplicated pregnancy. Her temperature is 36.8C, pulse 93 bpm, blood pressure 113/72 mmHg, and oxygen saturation 98% breathing air. Her booking blood pressure was 110/68 mmHg.

Urinalysis - negative
Ketones - negative
Blood - negative
Protein - 2+
Nitrites - negative
Leukocytes - negative
Which is the most appropriate next step in management?
Ask midwife to review in 2 weeks
Reassure and review at 36 week antenatal appointment
Refer for antenatal same day assessment
Send a mid-stream urine for microscopy, culture and sensitivity
Send a protein creatinine ratio

A

Refer for antenatal same day assessment

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32
Q

A 30 year old woman presents to General Practice 2 weeks after delivery of her first baby. She has low mood, exhaustion, difficulty sleeping, and is very tearful for the last week. She felt well during her pregnancy. She is bonding well with her baby and has good support at home. She has a history of depression but has been stable for the last 2 years. She has no thoughts of self-harm or suicide. Which is the most likely diagnosis?
Adjustment disorder
Baby blues
Dysthymia
Postnatal depression
Recurrent depression

A

Postnatal depression

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33
Q

A 35 year old woman in General Practice has epilepsy and is currently taking sodium valproate and desogestrel. She has not had a seizure for 13 months. She and her boyfriend would like to conceive a child. Which is the most appropriate management option?
Perform blood tests to check sodium valproate levels
Reduce sodium valproate dose
Refer to epilepsy clinic, continue current medication in the meantime
Refer to epilepsy clinic, meanwhile switch to a different anti-epileptic
Stop all medication now and refer to epilepsy clinic

A

Refer to epilepsy clinic, continue current medication in the meantime

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34
Q

A widespread rash is found on a 2 day old baby at his newborn check (see image). He is feeding well, is active and has no fever. What is the most appropriate management?

A

Nothing

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35
Q

A 6 year old girl with known sickle cell disease is in the Emergency Department with lethargy and shortness of breath. This is in the context of a recent febrile illness with a rash that has now resolved. Her blood results show: Hb 45 g/L (115 - 140), WBC 2.8 x 10^9/L (3.8 - 10), platelets 55 x 10^9/L (150 - 400). What pathogen is likely to have caused this presentation?

A

Parvovirus B19

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36
Q

The mother of a 3 year old boy in General Practice has noticed that her son’s foreskin is ballooning on urination. The foreskin is non-retractile. There is no redness or discomfort. What is the most likely diagnosis?

A

Phimosis

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37
Q

A 5 month old girl in General Practice has a worsening nappy rash for the last 2 weeks despite regular nappy changes, barrier cream and nappy-free time. She is feeding normally and otherwise well. Her temperature is 36.8C, and pulse rate 128 bpm. The rash is depicted in the image provided. What is the most appropriate management option in this scenario?

A

Keep clean and dry + barrier cream with castor oil and zinc

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38
Q

A 30 year old man with a brain injury following a road traffic accident reports experiencing an odd smell of burnt plastic. He is surprised that this is not bothering his flatmates. He recently reported seeing an image of Jesus on the walls of his bedroom reciting the ten commandments. What is the most likely diagnosis?

A

Post traumatic delirium

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39
Q

A 75 year old man with recurrent depressive disorder stopped taking his medication 1 month ago. He now has significant low mood and suicidal thoughts. He is admitted informally following an apparent attempt to hang himself. His wife died of cancer 2 years ago and he has no children. What level of observation should be provided by the ward nursing staff in this scenario?

A

1:1

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40
Q

A 61 year old man with alcohol dependence is brought to the Emergency Department by ambulance following concerns by neighbours. He presents with confusion and disorientation. He is irritable, tremulous and sweating. He appears to be responding to external visual stimuli. His temperature is 37.9C, pulse rate 125 bpm, BP 140/95 mmHg, respiratory rate 20 breaths per minute and oxygen saturation 95% breathing air. His breathalyser reading is 80 microgram alcohol / 100 mL of breath (legal limit for drivers <35). What is the most likely diagnosis?

A

Delirium tremens

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41
Q

A 13 year old boy attends the child psychiatry clinic with his parents, who describe a 7 month history of overeating. He frequently rummages through the cupboards at odd times of the day. He has said at times that he feels fat. His BMI is 18.5 kg/m2 (just under the 50th centile for his age). He has calluses on his knuckles. He performs well academically. What is the most likely diagnosis?

A

Bulimia nervosa

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42
Q

A 20 year old woman in the outpatient clinic has sudden episodes of palpitations, shortness of breath, sweating, chest pain and dry mouth. These episodes started 6 months ago, occur randomly and last for about 15 minutes. Education and lifestyle modification advice have not been helpful. What is the most appropriate next step in regards to her management?

A

CBT

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43
Q

An 18 year old girl in General Practice has had no periods for the previous 4 months. She had the contraceptive implant inserted 2 years ago. She reports missing meals as she has been stressed for her university exams. She admits to making herself vomit occasionally when she is stressed. Her temperature is 36.8C, pulse rate 65 bpm, BP 109/70 mmHg, BMI 17.5 kg/m2. A pregnancy test is negative. What is the most likely diagnosis? =

A

Anorexia nervosa

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44
Q

A 36 year old woman presents with spontaneous rupture of membranes at 33 weeks’ gestation. She has no abdominal pain. Speculum examination confirms a <1cm dilated cervix. She has no allergies. Her temperature is 36.6C, pulse 88 bpm, BP 110/55 mmHg, respiratory rate 16 breaths per minute, oxygen saturation 99% breathing air. What antibiotic should be prescribed in this scenario?

A

IV Benzylpenicillin

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45
Q

An active 50 year old who has no medical problems has a total abdominal hysterectomy for large multiple fibroids. She loses 300mls of blood. The procedure is uncomplicated. For how long should she be advised to take bed rest following discharge home?

A

6 weeks

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46
Q

A woman is due to have an elective caesarean section for breech presentation at 39 weeks’ gestation. For how many hours should she be fasted for solids prior to the operation?

A

6 hours

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47
Q

A 19 year old woman complains of irritability, aggression and low mood every month. She has no other medical conditions, takes no regular medication and is sexually active. The symptom diary shows that her work and social life are being affected in a cyclical way. What, specifically, is the aim of the hormonal management in this scenario?

A

Reduce premenstraul syndrome symptoms

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48
Q

A 27 year old woman has a complete molar pregnancy and only receives surgical management. She subsequently has regular serum beta-HCG monitoring. For how long should she be told to avoid pregnancy after the beta-HCG has returned to normal? (Your answer should be expressed numerically in the form: X months) =

A

12 months

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49
Q

A 24 year old woman with a BMI of 22 kg/m2, has an elective, uncomplicated laparoscopic procedure for removal of a 6 cm simple ovarian cyst. Assuming good postoperative recovery, after how long would she be appropriate to be discharged? (Your answer should be expressed numerically in the form: X hours)

A

24 hours

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50
Q

A 30 year old woman in the third trimester of her first pregnancy develops an itchy, bumpy rash on her abdomen, with sparing of the periumbilical area. She is usually fit and well and has had an uneventful pregnancy so far. What is the most likely diagnosis?

A

pruritic urticarial papules and plaques of pregnancy (PUPPP)

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51
Q

A 36 year old woman presents with a 4 day history of lower abdominal pain, dyspareunia and offensive vaginal discharge. She denies any bowel or urinary symptoms. She takes the combined oral contraceptive pill only and denies any missed pills. Her temperature is 38.2C. Her lower abdomen is mildly tender on palpation. Vaginal and speculum examinations are normal and pelvic swabs are taken. Her urine dipstick is normal. What is the most likely diagnosis?

A

Pelvic inflammatory disease

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52
Q

Woman with a little bit of pink post-coital bleeding on wiping. Smear is fine, ultrasound is clear. What is the next investigation?

A

TRIPLE SWAB

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53
Q

Total abdo Hysterectomy yesterday. Woman goes upstairs and faints. Normal BP. DX.

A

Vasovagal syncope/ortho hypotension

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54
Q

Gravidity and Parity - currently pregnant woman with hx of 1 x 37 week stillbirth, 1 x current 7 week pregnancy, 1 x premature baby, 1 x miscarriage

A

G5P2

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55
Q

Girl with dyskaryosis has colposcopy and biopsy showing CIN1. When should next colposcopy be?

A

1 year

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56
Q
  1. 5 y/o boy brought to GP with vague abdo pain. He has been having several loose bowel motions per day with occasional soiling of his underwear. His parents recall him passing a hard blood-streaked stool 5 days ago. Which is the most appropriate investigation?
    a. Colonoscopy with biopsies
    b. No investigations at this stage
    c. Stool microscopy, culture, and sensitivity
    d. Tissue transglutaminase antibody titres
    e. Urgent abdominal x-ray
A

anti-ttg? or no Ix

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57
Q
  1. 3 m/o boy presents in acute respiratory failure and is diagnosed with Pneumocystis pneumonia. His parents are first cousins from Pakistan. What is the most likely underlying cause?
    a. Agammaglobulinaemia
    b. Chronic granulomatous disease
    c. Cystic fibrosis
    d. HIV infection
    e. Severe combined immunodeficiency
A

SCID

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58
Q
  1. 2 y/o girl with loud barking cough and stridor is finding it increasingly difficult to breathe. Temperature 38.3, HR 190bpm, RR 53, O2 sats 92% on room air. Which is the most appropriate immediate treatment?
    a. Intravenous salbutamol
    b. Intubation and ventilation
    c. Nebulised adrenaline
    d. Nebulised salbutamol
    e. Oral dexamethasone
A

Nebulised adrenaline

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59
Q
  1. 14 y/o girl seen in GP for short stature. The mid-parental height is on the 50th centile. She has no secondary sexual characteristics. She is not taking any medications and is otherwise well, and her progress at school is satisfactory. Which is the most likely diagnosis?
    a. Constitutional delay
    b. Familial short stature
    c. Hypothyroidism
    d. Pituitary tumour
    e. Turner’s syndrome
A

Turner’s syndrome

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60
Q
  1. 18 m/o presents to GP with 1 day history of left ear pain. There is no discharge and mum reports normal number of wet nappies for that day. There is a bulging erythematous left tympanic membrane with no perforation. Temperature 38, HR 135, RR 33, O2 sats 98 on room air. What is the most appropriate management?
    a. Offer simple analgesia and an immediate prescription of amoxicillin
    b. Offer simple analgesia and ciprofloxacin ear drops
    c. Offer simple analgesia and delayed prescription of amoxicillin
    d. Offer simple analgesia and gentamicin ear drops
    e. Offer simple analgesia and reassurance
A

Offer simple analgesia and reassurance

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61
Q
  1. A 2 y/o in GP has worsening painful rash behind the knee for 5 days. He has eczema managed with E45 cream. Temperature 37.2, HR 130, RR 30, O2 sats 98%. What is the most appropriate management?
    a. Immediate referral to Paediatric A&E
    b. Give oral Aciclovir for 1 week
    c. Give oral Flucloxacillin for 1 week
    d. Give topical dermovate
    e. Give topical fusidic acid
A

go to A+E

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62
Q
  1. 11 y/o girl in GP with nausea, vomiting, headaches, and loss of appetite. School say she is starting to lag behind in class and has attended the school nurse regularly with playground falls. She is a healthy weight and has no focal neurology. What is the most appropriate next step?
    a. Immediately discuss with on call paediatrician
    b. Reassure and review in 4 weeks
    c. Refer for a non-urgent MRI brain scan
    d. Refer to neurologist under 2 week wait
    e. Routine bloods
A

Immediately discuss with on call paediatrician

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63
Q
  1. 35 y/o man presents to A&E agitated and requesting medication. He has mild tremor, cool and clammy skin, and goosebumps (piloerection). Ambulance staff found him in the street with an empty bottle of cider. Temperature 36.8, BP 140/100, HR 100. What is the most likely diagnosis?
    a. Alcohol intoxication
    b. Alcohol withdrawal syndrome
    c. Opiate intoxication
    d. Opiate withdrawal syndrome
    e. Tricyclic antidepressant intoxication
A

Opiate withdrawal syndrome

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64
Q
  1. 15 y/o girl has 12 months of irritable mood, lack of pleasure, poor sleep, poor concentration, and low appetite. She is struggling to concentrate at school and is getting into trouble for low marks. What is the most appropriate first-line treatment?
    a. Cognitive analytic therapy
    b. Cognitive behavioural therapy
    c. Family therapy
    d. Fluoxetine
    e. Sertraline
A

CBT

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65
Q
  1. 19 y/o woman with OCD is prescribed Sertraline at the maximum dose but it doesn’t control her symptoms. She has been unable to attend university for 4 months, and CBT has not helped in the past. What is the most appropriate next step in her management?
    a. Add another antidepressant
    b. Change to an antidepressant of another class
    c. Refer for additional and more intensive CBT
    d. Refer for deep brain stimulation
    e. Refer for ECT
A

Change to an antidepressant of another class

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66
Q
  1. 18 y/o man admitted under MHA to inpatient mental health unit for anorexia nervosa. He is commenced on nasogastric feeds and begins to show signs of confusion, weakness, and dyspnoea. Which electrolyte abnormality is most likely to be seen?
    a. Hypercalcaemia
    b. Hyperkalaemia
    c. Hypomagnesaemia
    d. Hyponatraemia
    e. Hypophosphataemia
A

Hypophosphataemia

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67
Q
  1. 25 y/o man attends A&E with headache. He is speaking rapidly and smiling as he talks. He scratches his skin constantly and claims to feel insects crawling up him. His temperature is 36.5, HR 130, and BP 154/84. What is the most likely diagnosis?
    a. Alcohol withdrawal
    b. Benzodiazepine withdrawal
    c. Cannabis intoxication
    d. Cocaine intoxication
    e. Heroin withdrawal
A

Cocaine intoxication

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68
Q
  1. 58 y/o man attends addiction services for initial alcohol dependence assessment. He regularly attends A&E following overdose attempts. He requests detoxification. He lives alone with few social contacts and has poorly controlled asthma. What is the most appropriate next step in management?
    a. CBT
    b. Community detoxification
    c. Disulfiram
    d. Inpatient detoxification
    e. Motivational interviewing
A

SURELY inpatient

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69
Q
  1. 28 y/o woman with history of depressive disorder is referred to community mental health team with a 3 day history of increased energy and restlessness; she has been working till 02:00 and writing new articles (she is the creative director of a magazine). She recognises that this is unusual for her, describes her mood as 10/10, and says she feels creative and full of ideas. What is the most likely diagnosis?
    a. Agitated depression
    b. Hypomania
    c. Manic episode
    d. Schizoaffective disorder
    e. Schizophrenia
A

Hypomania

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70
Q
  1. 24 y/o seen in GP for 6 months of low mood, poor concentration, and trouble sleeping. He denies suicidal ideation or self-harm. He denies drinking excessively, smoking at all, and using recreational drugs. He is a waiter and is struggling at work and has a PHQ-9 of 6 (mild severity). What is the most appropriate course of action?
    a. Advise mindfulness classes
    b. Refer for CBT
    c. Start Citalopram
    d. Start Fluoxetine
    e. Write a fit note (medical certificate) for 4 weeks
A

Refer for CBT

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71
Q
  1. 42 y/o woman is 34 weeks pregnant and has had repeat admissions for severe abdominal pain. She currently needs opiate analgesia but is still struggling with the pain. USS shows a sub-serosal fibroid measuring 7cm x 9cm. What is the best management option for her pain?
    a. Continuous regular opiates
    b. Epidural anaesthesia
    c. NSAIDs
    d. Remifentanyl patient-controlled analgesia
    e. Uterine artery embolisation
A

Continuous regular opiates

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72
Q
  1. 40 y/o woman is successfully treated for ectopic pregnancy with methotrexate. After what interval may she safely conceive again?
    a. 1 year
    b. 3 months
    c. 6 months
    d. Her next menses
    e. Immediately
A

3 months

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73
Q
  1. A woman is having a repeat USS at 32 weeks gestation for a previously low-lying placenta. The USS shows the placenta is clear of the cervical os and an additional succenturiate lobe is seen. Which condition needs to be excluded in the USS?
    a. Cervical shortening
    b. Fetal growth restriction
    c. Placenta praevia
    d. Vasa praevia
    e. Velamentous cord insertion
A

Vasa praevia

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74
Q
  1. 63 y/o woman presents with a 2 week history of post-menopausal vaginal bleeding. BMI is 39.2. Pelvic USS shows irregular endometrial thickening (14mm). Outpatient endometrial sampling fails because of cervical stenosis. What is the most appropriate management?
    a. CT abdomen and pelvis
    b. Hysteroscopy with dilatation and curettage
    c. Repeat USS in 2 weeks
    d. Total abdominal hysterectomy + bilateral salpingo-oopherectomy
    e. Total laparoscopic hysterectomy + bilateral salpingo-oopherectomy
A

Hysteroscopy with dilatation and curettage

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75
Q
  1. 29 y/o woman with past history of cocaine and cannabis use denies using for the past 3 years. Which additional test should be done for this patient at booking?
    a. Hair toxicology screen
    b. Hepatitis C
    c. Hepatitis E
    d. Serum toxicology screen
    e. Urine toxicology screen
A

Hep C

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76
Q
  1. 33 y/o woman has Ventouse delivery at 39 weeks gestation and requires manual removal of placenta. The removal is uncomplicated with an EBL of 600ml. She plans to mix feed her baby for the first 6 months. When can she expect her menstrual cycle to return?
    a. Cannot be predicted
    b. When she is more than 50% bottle feeding
    c. When she stops breastfeeding
    d. Within 6 months
    e. Within 6 weeks
A

CANNOT predict

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77
Q
  1. 29 y/o attends A&E with SOB, abdo pain, nausea, bloating, and feeling faint. She is having her first cycle of IVF and had her embryo transfer 3 days ago. What is the most likely diagnosis?
    a. Ectopic pregnancy
    b. Miscarriage
    c. Ovarian hyperstimulation syndrome
    d. Pulmonary embolism
    e. Ruptured ovarian cyst
A

Ovarian hyperstimulation syndrome

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78
Q
  1. 60 y/o woman presents with discomfort during sex and vaginal dryness. What is the best management option?
    a. Commence oral HRT
    b. Commence SSRI
    c. Commence topical vaginal oestrogen
    d. Commence transdermal HRT
    e. Commence vaginal lubricants
A

Commence topical vaginal oestrogen

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79
Q
  1. 32 y/o woman has diagnostic laparoscopy to investigate pelvic pain, and has a catheter inserted in recovery for urinary retention. The catheter is removed the next morning. When can she be safely discharged home?
    a. When she has voided more than 200ml
    b. Straight away with advice to return if she has problems voiding
    c. When her post-void residual volume is 0ml
    d. When her post-void residual volume is 100ml
    e. When her post-void residual volume is 300ml
A

When her post-void residual volume is 100ml

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80
Q
  1. 25 y/o woman who is 38 weeks pregnant is seen in triage for irregular painful contractions lasting 6 hours. She took paracetamol 6 hours ago. She is examined and found to be 2cm dilated. Which analgesia is most appropriate?
    a. Co-dydramol
    b. Epidural analgesia
    c. Nitrous oxide
    d. NSAID
    e. Warm bath
A

co-drydamol

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81
Q
  1. 41 y/o women attends her dating scan. LMP dates make her 12 weeks pregnant. An intrauterine pregnancy is seen with no fetal heartbeat. CRL is equivalent to a fetus of 9 weeks gestation. What is the best next step?
    a. Admit her for laparoscopy
    b. Counsel her on management options for miscarriage
    c. Offer her a repeat USS in 1 week
    d. Offer treatment with methotrexate
    e. Serum beta-hCG now and repeat in 48 hours
A

Counsel her on management options for miscarriage

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82
Q
  1. 37 y/o woman has her anomaly scan at 20+3 weeks of pregnancy, and it reveals echogenic bowel. What is the most likely cause?
    a. Duodenal atresia
    b. Incidental finding
    c. Male gender
    d. Trisomy 18
    e. Trisomy 21
A

trisomy 21

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83
Q
  1. A Rh negative woman has light vaginal bleeding and pain at 9 weeks gestation. USS shows a viable 9 week intrauterine pregnancy. The bleeding resolves 48 hours later. What further treatment does she require?
    a. 250IU Anti-D prophylaxis immediately
    b. Kleihauer test
    c. No further action
    d. Progesterone pessaries
    e. Repeat scan in 2 weeks
A

no further action

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84
Q
  1. 42 y/o Afro-Caribbean woman presents with ongoing menorrhagia. A uterine fibroid is identified on TVUSS, and a trial of tranexamic acid has not helped. Which is the next most appropriate management step?
    a. COCP
    b. Intrauterine coil device
    c. IUS
    d. Mefenamic acid
    e. Refer to gynaecology
A

IUS

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85
Q
  1. 36 y/o woman sees GP for routine appointment at 32 weeks pregnancy. This is her first pregnancy and has so far been uncomplicated. She has normal fetal movements and is generally well with temperature 36.3, HR 90, BP 128/82, RR 13, O2 sats 96% on room air. Fundal height is 32cm and fetal HR is normal. Urine dipstick shows ++ protein but no other abnormalities. What is the most appropriate management?
    a. Immediate referral to obstetrics
    b. Repeat urinanalysis in 1 day
    c. Repeat urinanalysis in 1 week
    d. Send urine for MC&S and start Nitrofurantoin
    e. Send urine for MC&S and start Trimethoprim
A

Immediate referral

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86
Q
  1. 19 y/o woman in GP has a 3 week history of post-coital vaginal bleeding. She had a Nexplanon (Progesterone-only subdermal implant) inserted 18 months ago and has been amenorrhoeic for the last 12 months. Vaginal and speculum exams are normal and urine pregnancy test is normal. What is the most appropriate next investigation?
    a. Blood test for clotting screen
    b. Cervical cytology
    c. Endocervical, chlamydial, and high vaginal swabs
    d. Transvaginal USS
    e. Urine for microscopy, culture, and sensitivities
A

Endocervical, chlamydial, and high vaginal swabs

87
Q
  1. 19 y/o woman attends GP for contraception review. She started Microgynon-30 14 months ago and reports a recent migraine without aura which lasted 2 days (which she has never experienced before). She is currently a smoker but has no other CVS disease or VTE risk factors. Her temperature is 36.5, HR 70, BP 115/63, RR 14, O2 sats 97% on room air, and her BMI is 21. What is the most appropriate next step in management?
    a. Continue Microgynon-30 and offer smoking cessation
    b. Continue Microgynon-30 and start Sumitriptan
    c. Stop Microgynon-30 and offer Microgynon-20
    d. Stop Microgynon-30 and offer progesterone-only contraception
    e. Stop Microgynon-30 and start NuvaRing
A

Stop Microgynon-30 and offer progesterone-only contraception

88
Q
  1. 26 y/o woman has 24 hours of vulval rash and painful urination. What is the most appropriate treatment?
    a. Oral aciclovir
    b. Oral flucloxacillin
    c. Topical aciclovir
    d. Topical clotrimazole
    e. Topical fusidic acid
A

oral aciclovir

89
Q
A
90
Q
  1. 29 y/o seen in GP wanting to conceive. She has epilepsy and her last seizure was 18 months ago. She currently has a copper IUD in situ and is taking sodium valproate 1000mg BD. What is the most appropriate management?
    a. Leave IUD in situ, continue sodium valproate, and refer her for specialist advice
    b. Remove IUD, continue sodium valproate 1000mg BD and start folic acid 5mg OD
    c. Remove IUD, stop sodium valproate 1000mg and start carbamazepine 600mg BD and folic acid 5mg OD
    d. Remove ID, stop sodium valproate, and start folic acid 400mcg OD
A

Leave IUD in situ, continue sodium valproate, and refer her for specialist advice

91
Q
  1. 32 y/o woman presents to GP with dyspareunia, sweating, and low mood. She has not had a period in over a year, and has previously been treated with chemotherapy for breast cancer. What is the most appropriate investigation?
    a. LH and FSH
    b. Oestradiol level
    c. Pelvic USS
    d. Prolactin
    e. Testosterone
A

LH/FSH

92
Q

16 hour old baby is jaundiced, has yellow stools, is sleepy, and is not feeding. The mother was positive for Group B Streptococcus in her previous pregnancy. What is the most likely diagnosis?

A

Group B Streptococcus Sepsis

93
Q
  1. A baby is born with 45XO karyotype. What is the most likely cardiac abnormality associated with this syndrome?
A

Bicuspid aortic valve

94
Q
  1. 15 y/o boy has worsening severe headaches for 1 month and has been vomiting in the morning. There is no history of trauma and he is afebrile. What definitive investigation should now be requested?
A

Brain MRI

95
Q
  1. Child has symptoms of perennial rhinitis (blocked nose, nasal voice, running eyes). What is the most likely causative allergen in this scenario?
A

DUST MITES

96
Q
  1. 2 y/o girl has a fever of 39.7 and a painful, swollen right eye with preserved eye movements (see picture below). What is the most appropriate first-line treatment?
A

Oral co-amoxiclav

97
Q
  1. 15 y/o girl weighs 100kg. She has striae and darker skin in her armpits and neck. She has been feeling tired and has had episodes of vulval thrush, but is otherwise well. A blood test shows a fasting blood glucose of 7.6mmol/L (3-6 normal range). What pharmacological treatment should be considered?
A

metformin

98
Q

Mother with SLE has a baby who is born with a slow heartbeat. What is the most likely diagnosis?

A

congenital heart block

99
Q
  1. 13 y/o girl seen in GP with fever, sore throat, and cervical lymphadenopathy. Her temperature is 37.9 and she has white exudates on enlarged tonsils. She is prescribed Amoxicillin 500mg TDS, then 7 days later re-presents with a widespread rash (see picture below). What is the most likely causative organism?
A

EBV

100
Q
  1. 27 y/o woman reviewed by community mental health team for schizophrenia follow-up. She describes experiences where she thinks she isn’t real. What phenomenon is this?
A

derealisation

101
Q
  1. 55 y/o man admitted to hospital 3 days ago for knee replacement. Now complaining of seeing ants crawling up his legs and appears confused and tremulous. What is the most likely diagnosis?
A

delirium tremens

102
Q
  1. 11 y/o boy excluded from school following destructive behaviour including arson and aggressive behaviour towards peers. He has repeatedly been cautioned by police for shoplifting. What is the most likely diagnosis?
A

conduct disorder

103
Q
  1. 50 y/o man believes wife is cheating on him, gathering evidence by repeated obsessive examination of her underwear. What is the most likely psychiatric diagnosis?
A

Othello syndrome

104
Q
  1. 20 y/o man with schizophrenia tells his support worker that the TV news presenter talks about him. What psychotic phenomenon is he describing?
A

3rd person auditory hallucination

105
Q
  1. 78 y/o woman has 2 weeks of progressive lethargy, nausea, and dizziness. She has depression and has recently increased her dose of Citalopram. What is the most likely biochemical abnormality?
A

hyponatremia

106
Q
  1. 22 y/o woman has 6 months of restricted eating, amenorrhea, social anxiety, and low mood. She has fine hair on her face and her BMI is 16.8. Her observations are otherwise normal. What is the most appropriate first-line pharmacological intervention?
A

SSRI - fluoxetine

107
Q
  1. 35 y/o woman has frothy and thin offensive yellow vaginal discharge. She is afebrile and last has sexual intercourse 3 weeks ago. She describes dysuria for the last few days and soreness and itchiness of her vulva. What is the most likely diagnosis?
A

TV

108
Q
  1. Which 4 strains of HPV are targeted by the current UK quadrivalent vaccination program?
A

6, 11, 16, 18

109
Q
  1. 8 y/o girl brought to gynaecology clinic with offensive vaginal discharge, but is otherwise well. What is the most likely cause?
A

foregin body

110
Q
  1. 40 y/o woman has had miscarriages at 8 weeks, 11 weeks, and 22 weeks. She has also had one ectopic pregnancy for which she had a laparoscopic salpingectomy. Last year she has a stillbirth at 24 weeks gestation. She has one 4 year old daughter delivered at 39 weeks by C-section, and is currently 6 weeks pregnant. What is her gravidity and parity (express as GxPx)?
A

G7P2 + 4

111
Q
  1. 28 y/o woman has a regular 35 day cycle. The first day of her LMP is 27/11/2019. What is her estimated delivery date?
A

09/09/2020

112
Q
  1. 49 y/o woman has heavy, irregular menstrual bleeding. TVUSS shows a thickened endometrium with cystic spaces. What investigation would be diagnostic in this scenario?
A

biopsy

113
Q
  1. 32 y/o with mild asthma has unexplained intra-uterine death at 37 weeks gestation. She is induced and has epidural analgesia and a spontaneous vaginal delivery. She is very distressed and would like to go home. What should be given to prevent her from expressing breast milk in this scenario?
A

Cabergoline

114
Q
  1. 21 y/o woman is 5 weeks pregnant with abdominal pain. USS shows no evidence of an intrauterine pregnancy, a corpus luteum in the left ovary, and otherwise normal adenexae. Her serum b-hCG is 700 (<18 normal range). How should this pregnancy be classified?
A

Pregnancy of unknown location

115
Q

Baby born 1 day ago. what is this

A

erythema toxicum

116
Q

Neonate had just one episode of billous vomiting. What should be done?

A

admit into neonate unit and assess and observe

117
Q

Hand foot and mouth Tx

A

nothing - supportive

118
Q

Child is brought in as they have a fever of 37.8 or sth (mild), 12 hours after the Meningiococcal vaccine was given that morning. What do?

A

reassure and safety net

119
Q

Worst prognostic factor of schizophrenia?
male, gradual onset, negative social withdrawal symptoms, positive affective symptoms, university education

A

gradual onset

120
Q

Woman is 20 weeks, says she’s going to FGM to the child when born because it’s her culture and she’s had it. What is the first/best (?) management?
Safeguarding, give her leaflets, call the police, call social services

A

safeguarding

121
Q

Pregnant lady with bullous rash on R forearm, started at umbilicus and spread from there.

A

pemphigus gestationis

122
Q

63 yo lady just had a vaginal hysterectomy, she works as a carer in a care home. How long does she have to take off work assuming she has no complications?

A

4 weeks

123
Q

Woman has an intrauterine device/system put in. How often does she have to check for the strings?
Every 3m, every 6m, not at all, after coitus (specifically wrote coitus not sex bc idk why), after menstruation

A

after menstruation

124
Q

Woman pregnant RFM at 36w, CTG normal after some time of monitoring, similar episodes at 30, 32 weeks, something like what should you offer now?
Doppler, USS growth scan, induce labour now, c section,

A

USS growth scan

125
Q

Women recently underwent LLETZ for CIN(1 or 2?), when should next smear be?

A

6 months

126
Q

32 weeks Pregnant woman had fall, fell on abdomen, Well in herself, no bruising or haemorrhage. Third pregnancy, is Rhesus negative. What should be done?

A

anti-D and kleihauer

127
Q

Pregnant woman with swelling in lower leg. Some other details. What should be done?

A

prophylactic LMWH

128
Q

Best test for predicting preterm labour?

A

Cervical length

129
Q

Neonate, no femoral pulses, hepatomegaly, blue. Dx?

A

coarctation of the aorta

130
Q

Child being exclusively fed bottle feed at 2 months. Starts crying during AND after feeds, arches back. Dx?

A

gord

131
Q

Girl with barking cough and stridor. What is the scoring system for this condition?

A

westley croup score

132
Q

Mum comes in with child, she saw him swallow a 20p coin in the garden 30 mins ago, no choking, coughing, blood etc. Whats the best investigation?

A

metal detector

133
Q

Lady w schizophrenia and actively psychotic declines some physical health intervention, which is the best framework (“act”) to provide treatment under?

A

mental capacity act

134
Q

What anti-depressant medication causes gynecomastia

A

amitriptylline

135
Q

Women presenting with hyperreflexia, tremor etc, what drugs did she likely overdose on?

A

lithium

136
Q

Baby felt on examination to have the fontanelle with 4 suture lines coming out of it at 12 o’clock, what position is the baby?

A

occipito-posterior

137
Q

Catheter out after hysterectomy, how many hours until urination?

A

4 hours

138
Q

65F medium size multi loculated cyst on USS, next investigation?

A

Ca125 then TVUSS

139
Q

Older lady comes in with feeling of bearing down. She needs to digitate her vagina to defacate every time. Name which exact type of vaginal prolapse she has?

A

RECTOCOELE

140
Q

Women had had previous miscarriage, where Trisomy 21 found at ?16 weeks. Now pregnant again, wants to know what testing she can have for Down’s syndrome??

A

quadruple test

141
Q

. You suspect a lady who is 35 years old, G4P3 30+6 might have a PE. You would like to investigate her for this. US doppler of the lower limbs comes back normal but you still strongly suspect a PE. She has a strong family history of breast cancer and is worried about radiation to her breast tissue. Which investigation would be most appropriate for her? * 哚
* Repeat US doppler LL
* V/Q scan
* СтРА
) CT chest
CXR

A

V/Q scan

142
Q

Which type of ovarian cancer typically affects young women under the age of 20? *
Mucinous adenocarcinoma
* Serous adenocarcinoma
Krukenberg tumour
* | Dysgerminoma
Clear cell adenocarcinoma

A

dysgerminoma

143
Q
  1. You are asked to perform an ARM for a lady with GDM who was breech yesterday, but is cephalic today. The head is high and she is known to have polyhydramnios. Which emergency are you anticipating imminently? *
    Pre-eclampsia
    Shoulder dystocia
    Umbilical cord prolapse
    * Undiagnosed breech
    Post-partum haemorrhage
A

cord prolapse

144
Q

Which is not a common cause for oligomenorrhoea? * Anovulation
Puberty
Peri-menopause
Copper IUD
Obesity

A

copper IUD

145
Q

According to the NICE guidelines, when is it inappropriate to use ultrasound appearances of the ovaries to make a diagnosis of PCOS? *
In patients with diabetes
During adolescence
* Previous unilateral oophorectomy
* When using transabdominal ultrasound
In postpartum women

A

adolescence

146
Q

Which of the following does not increase your risk of endometrial cancer? *
Obesity
* Older age
Tamoxifen
* Polycystic ovarian syndrome
* Combined oral contraceptive pill

A

COCP

147
Q
  1. Which statement about contraception is true? *
    Both levonorgestrel and ulipristal can be used more than once in the same cycle as emergency contraception
    * The Mirena® Coil - levonorgestrel 20 mcg/24 hrs is effective for at least 10 years
    * * The progesterone injection is not associated with weight gain
    * ) The contraceptive implant is contraindicated 4wks after delivery
    Migraine with aura is UKMEC 3 for starting a patient on the combined oral contraceptive pill
A

Both levonorgestrel and ulipristal can be used more than once in the same cycle as emergency contraception

148
Q

What value corresponds with Down’s syndrome on antenatal genetic testing? *
hCG = low
Oestriol = low
PAPP-A = high
* Nuchal Translucency = reduced
* Inhibin A = normal/low

A

low oestriol

combined test result for down’s = low PAPP-A, high hCG, thickened nuchal translucency

quadruple test result for down’s = low oestriol, low AFP, high hcG, high inhibin A

149
Q
  1. During the evaluation of secondary amenorrhea in a 24-year-old woman, hyperprolactinaemia is diagnosed. Which of the following conditions could cause increased circulating prolactin concentration and amenorrhea in this patient? *
    Stress
    Primary hyperthyroidism
    Anorexia nervosa
    Congenital adrenal hyperplasia
    Polycystic ovarian disease
A

STRESS

150
Q
  1. Lumacaftor is a novel drug used to treat Cystic Fibrosis. What is it’s mechanism of action? *
    Breaks down mucus within the airways
    * Opens up non-functioning channels (potentiates channels)
    * Increases pancreatic exocrine function
    Enhances ciliary motility
    Prevents misfolding and increases protein trafficking
A

Prevents misfolding and increases protein trafficking

151
Q
  1. A neonate born at 34 weeks is found in NICU to be passing bloody stools and have profound abdominal distension. Given the likely diagnosis, the consultant asks the keen medical student what would be an X-ray sign for an urgent laparotomy? *
    * Rigler sign
    * Line of Klein
    * Sail sign
    * Battle sign
    * Kerley B lines
A

rigler sign

152
Q
  1. Clara is a 34-year-old female who has developed manic symptoms following the delivery of her first baby 3 years ago. Now she and her partner present to the pre-conception clinic, anxious to find out the chance of her mental health illness relapse in future pregnancies? *
    1 in 2
    1 in 5
    * ) 1 in 50
    * 1 in 100
    ) 1 in 500
A

1 in 2

153
Q

. A 17-year-old female with BMI of 17 believes she is obese. She is always on a low calorie diet and walks excessively. She reports a regular menstrual cycle.
What is the most likely diagnosis? *
Anorexia nervosa
Atypical anorexia nervosa
Body dysmorphic disorder
Bulimia nervosa
Normal teenage presentation

A

atypical anorexia nervosa

154
Q

Kid with episodes of stiffening of hands and limbs, accompanied by screaming and sweating. diagnosis?

A

Anoxic reflex seizure

155
Q

Question on a kid who had bloods that demonstrated: low platelets, normal white cells and normal red cells.

A

ITP

156
Q

7 year old kid headache and secondary nocturnal enuresis. He’s lost 1.5kg. Urine dipstick normal (i.e. no glucose, proteins, blood. Specific gravity ?1.010 to 1.030) What is the likely diagnosis? Urinalysis nil (plasma osmolality not given?). Diabetes insipidus, diabetes mellitus, behavioral enuresis, constipation

A

DI

157
Q

Voraciously hungry kid, hypotonia and almond eyes what was the diagnosis? Initial problems feeding and almond eyes.

A

prader-willi

158
Q

Kid who had rashes which had crusted over and he was also scratching them and now he had a peak fever and cool peripheries. What is the cause for his acute presentation?
Varicella zoster viraemia, Streptococcal bacteraemia, Meningococcal bacteraemia, herpes simplex viraemia

A

streptococcal bacteraemia (superinfection)

159
Q

Another case with an unwell child where chest was clear, had a fever. Lost weight recently. What do you do next? Glucose, CXR, urine dip, ABG

A

glucose

160
Q

Kid growing along the 55th centile and is vomiting after food. He was bottle and breast-fed. So what is the cause?

A

GORD

161
Q

Baby who just started solid foods and was being weaned or something and has become constipated. What do you do?

A

MOVICOL

162
Q

Child who has a hx of very dry skin, rash over arms, getting worse & spreading to ?extensor surfaces. Sister has itchy rash on ankles and wrists. MANAGEMENT?

A

emollients+1% hydrocortisone

163
Q

Child is 12w, what would be an absolute contraindication to vaccintion for kids? Acute fever <38.4oC, severe cows milk protein intolerance, previous large erythematous rash at injection site, sibling with some reaction, whooping cough at 6w

A

acute fever

164
Q

Uncle gets TB, kid lives with him, Mantoux test showed a number between 10-14mm for the result. What should you do?

A

start anti-TB Tx (POSITIVE RESULT IS >10mm)

165
Q

Precocious puberty (5yo and has sparse axillary and pubic hair as well as breast bud development) and high centile growth parents are along some lower centile. What definitive diagnostic test do you do?

A

gonadotrophin stimulation test

166
Q

Cerebral Palsy (described hemiplegic weakness with brisk reflexes), what area of the brain is affected?

A

motor cortex (hemiplegic)

diplegic/quadaplegic = pyramidal

167
Q

Kid needs fluids, but you can’t get standard IV access. Where do you go?

A

intraosseous

168
Q

HIV with undetectable viral load. what is contraindicated in labour?

A

foetal blood sampling

169
Q

Woman with rupture of membranes, painless bleeding and something along those lines. What was the likely diagnosis?

A

vasa praevia

170
Q

What do you do for a woman in labour after 4 hours of checking, she’s like 4cm or something. Prostaglandins, Cervical sweep, Oxytocin, Ergometrine, ARM

A

ARM

171
Q

Woman with high BMI (28) who basically had stress incontinence. What’s the first line management? Pelvic floor exercises, oxybutinin, bladder training, weight loss

A

PELVIC FLOOR EXERCISES

172
Q

Woman with endometriosis, had laparoscopic adhesiolysis - had a whole range of sx - high CRP, low Hb, constipation, bowel sounds absents etc - what’s happened? Bowel obstruction perforation, urinary retention, intrabdo bleeding

A

perforation

173
Q

Woman at term has just SROM’d, transverse lie clear liquid but fetal distress, why? Cord prolapse, vasa previa, placenta previa, placental abruption, uterine rupture

A

cord prolapse

174
Q

Some girl with anorexia was admitted and she started eating and stuff. Then she gets muscle spasms, and abdominal pain and stuff. What would be deranged/ what’s the most important thing to check for?

A

phosphate

175
Q

Guy on haloperidol gets muscle probleums

A

IM procyclidine

176
Q

Guy on antipsychotic comes in with tremor- most likely drug

A

haloperidol

177
Q

patient with dilated pupils, urinary retention, obs normal-ish - cause of overdose?

A

TCAs

178
Q

Woman is pregnant and HIV negative at booking but her partner is HIV positive - what do you do?

A

nothing

179
Q

What signifies onset of active labour?

A

> 4cm dilation
contractions every 3-4 mins lasting 45-60s

180
Q

Couple seen in subfertility clinic and the female and male investigations are given (with normal ranges for sperm count, FSH etc etc). Results show azoospermia. How should they be managed? IVF, egg donation, ICSI, IUI

A

ICSI

181
Q

Ovarian cyst with ground glass appearance

A

endometrioma

182
Q

Woman has pain before periods and has been subfertile, cyst found on ovary. what is it?

A

endometrioma

183
Q

Lady is on Tamoxifen, which cancer does this increase the risk of?

A

Endometrial cancer

184
Q

3 months old baby with signs of HF, systolic murmur that radiates over the praecordium -

A

VSD

185
Q

What is the most important thing to look at in follow up of HSP?

A

urine protein and RBCs

186
Q

6 year old child with 24 hour history of left peri-orbital swelling. Had an upper respiratory tract infection last week. Left proptosis, visual acuity was normal and had a fever of 38.9. What is the best diagnostic investigation?

A

CT of nasal orbits

187
Q

Child with fever, white exudate on one tonsil, diagnosis?

A

quinsy

188
Q

Child with episodes of smelling strange things, hard to communicate with during these episodes, falls asleep for an hour after and doesn’t remember anything. Diagnosis?

A

focal seizure

189
Q

Nappy rash with satellite lesions

A

candida - topical nystatin or imidazole

190
Q

Woman comes in with a pneumothorax and said her husband kicked her and has previously hurt their baby too. Baby is currently at home with him - what do you do?

A

call police

191
Q

Woman wants to terminate her 8 week pregnancy because she already has 3 children - which clause of the abortion act does this fall under

A

A

192
Q

Woman in stage 2 of labour, pushing for 30 minutes, head pressing against perineum, when CTG becomes pathological - what do you do next? Emergency C section, forceps delivery, episiotomy

A

Episiotomy

193
Q

Woman has come for a sterilisation, has had protected sex (definitely protected) since her last menstruation one week ago, just post-ovulation - immediate Tx? Insert IUD, Cancel surgery, Continue with Surgery.

A

proceed with surgery

194
Q

Which test for Down syndrome screening at 15 weeks?

A

NIPT

195
Q

Previous baby 5.1Kg and mother has diabetes, fasting glucose and OGTT normal - what extra tests should be arranged for her?

A

OGTT at 24-28 weeks

196
Q

Deficiency of what vitamin is causing visual disturbances, ataxia and confusion

A

thiamine (B1 deficiency)

197
Q

risk of schizophrenia if person has a FHx

A

10-15%

198
Q

Treatment for patient with manic episode

A

olanzapine

199
Q

Girl witnesses car crash and goes few hours later blind. Dx

A

conversion disorder

200
Q

Treatment for torticollis

A

procyclidine

201
Q

3 year old girl with tiredness and snoring, and frequent coughs and colds, and speech was normal but difficulty articulating words. What Ix

A

karyotyping for down’s syndrome

202
Q

On newborn check, inverted ankles and plantar flexed, what sign is this?

A

talipes equinovarus

203
Q

Difficult balance, cannot build block of towers, hyperreflexia. Where is lesion?

A

cerebellum

204
Q

Medication for neonate in respiratory distress on oxygen

A

surfactant

205
Q

Kid with hepatomegaly and breathlessness - Ix

A

CXR

206
Q

Maintenance fluid to give to kid with diabetes mellitus

A

0.9% saline

207
Q

Man with azoospermia. What would be the most likely cause?

A

MUMPS

208
Q

heart sound not heard, scaphoid chest.

A

congenital diaphragmatic hernia

209
Q

Baby born at 37 weeks, via forceps. Showing signs of resp distress. CXR shows areas of consolidation throughout.

A

TTN

210
Q

Prem baby, resp distress, CXR looks like ground glass

A

surfactant deficiencty - RDS

211
Q

Scabies Tx

A

permethrin

212
Q

Man with treatment resistant schizophrenia on clozapine, recently stopped smoking. High level of clozapine now. Most likely consequence?

A

constipation, seizures, ileus

213
Q

Definition of feel insects under skin.

A

formication