Wound Healing Flashcards
Describe the body’s defense in would healing.
- Stop the blood loss.
- Clean up pathogens.
- Seal wound against infection.
- Regenerate natural epidermal covering.
- Repair deeper tissue damage.
What are the main phases of healing?
- Inflammation
- Proliferation
- Remodeling
What happens during the inflammation phase?
- hemostasis
- phagocytosis
- edema
Up to 7 Days
What happens during the proliferation phase?
- Epithelization
- Neovascularization
- Collagen synthesis
- Contraction
Up to 20 Days
What happens during remodeling?
- Tensile strength
- Collagen remodeling
Up to 2 Years
How soon does hemostasis begin?
0 to 2 hours, as soon as the incision is made.
Hemostasis occurs ______.
Within seconds, by vasoconstriction. Platelets aggregate to form a clot.
How soon does phagocytosis happen?
0-4 days. Wound is red and swollen.
How soon does Edema occur?
0-6 days
What does the wound look like when phagocytosis occurs?
Wound is red and swollen.
Phagocytosis occurs when…
Phagocytosis occurs when neutrophils and macrophages appear to digest and dispose of pathogens and debris.
What happens during edema?
Capillary walls become permeable to plasma. Plasma leaks into wound, causing edema.
Proliferation phase starts _____ and continues until ____.
Proliferation starts the second day after incision and continues until 22nd day.
What are the events in proliferation?
Epithelialization
Neovascularization
Collagen Synthesis
Contraction
When does epithelialization occur?
1 to 4 days
What happens during epithelialization?
Fibroblasts migrate toward the wound site. Keratinocytes begin the formation of a scab sealing of the wound.
When does neovascularization occur?
2-7 days
The time period when most wound disruptions occur?
Neovascularization.
When does collagen synthesis happen?
2 to 22 days.