Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Wound Healing > Wound Healing > Flashcards

Wound Healing Flashcards

1
Q

“stoppage of bleeding”

A

Hemostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Two steps of Hemostasis

A

Vasoconstriction and clotting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

causes vasoconstriction

A

thromboxane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

components of a clot

A

aggregated platelets and fibrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

precursor that produces platelets, activated by thrombopoetin

A

magakaryocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

initiate platelet activation

A

agonist receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

result of platelet activation and aggregation

A

platelet plug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

cause platelet aggregation/ adhesion to collagen

A

ligand receptors - specifically von Willebrand Factor binding to GPlb-IX receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Secreted during platelet plug formation causing surface to become negative

A

granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

clotting factors of fibrin follow down a path causing the proteolytic cleavage of each other - path is called?

A

Cascade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

problems with factor IX and VII causing inability to clot

A

hemophilia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

subpathways of clotting cascade

A

intrinsic pathway and extrinsic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

subpathways follow same path starting at this step

A

prothrombin to thrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

damages surface causes the cascade - contact activation

A

intrinsic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

trauma releases tissue factor and causes the cascade

A

extrinsic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

catalyst that converts fibrinogen into fibrin

A

thrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

insoluble component that crosslinks and aggregates laterally to form a clot

A

fibrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

precursor to fibrin

A

fibrinogen (activated by thrombin to forn fibrin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

converts glutamic acid to y-carboxyglutamate forming specific clotting factors such as thrombin that are very good at binding Ca2+

A

Vitamin K

20
Q

inhibits cyclo-oxygenase from converting archidonic acid to endoperoxides in platelet activation

A

Aspirin

21
Q

anticoagulation drug that inhibits activity of Vit K

A

Warfarin

22
Q

blocks platelet agonist receptors, so platelets cannot be activated

A

Plavix (platelet activation nixed - good way to remember)

23
Q

anticoagulant “anti-thrombin” inhibits thrombin so fibrin clot cannot form

A

Heparin

24
Q

anticoagulant commonly used in blood extractions to prevent clotting in tubes

A

EDTA

25
Q

cleavage of fibrin - dissolving the clot

A

fibrinolysis

lysis of fibrin

26
Q

what is activated to form the enzyme that carries out the cleavage of fibrin?

A

plasminogen

27
Q

plasminogen is activated by what to form plasmin

A

TPA

28
Q

the enzyme that carries out the cleavage of fibrin

A

plaminogen

29
Q

come from platelet granules, signal to indicate cell damage and presence of foreign microorganisms

A

cytokines

30
Q

types of cytokines

A

interleukins, growth factors, and chemokines

31
Q

order of cells involved in inflammation

A

Neutrophils
Macrophages
Lymphocytes
(backwards alphabetical NML)

32
Q

first responders in inflammatory response, cause phagocytosis and degranulation

A

Neutrophils

33
Q

organize and regulate, phagocytosis, and cytokine production

A

Macrophages

34
Q

the adaptive inflammatory response, T Cells, and B cells

A

Lymphocytes

35
Q

Cell type in repithelialization

A

Keratinocyte Stem Cells

36
Q

Cell type in granulation of tissue

A

fibroblasts

37
Q

fibroblast cells that cause wound contraction

A

myofibroblasts

38
Q

Cells that deposit connective tissue

A

Fibrin and Fibronectin

39
Q

transmembrane proteins bound to ECM and actin skeleton allowing for signaling and adhesion

A

integrins

40
Q

four steps of bone healing

A

stem cell recruitment,
deposition of bone,
Vasucularization, Remodeling

41
Q

remodeling of bone moves from this type of bone to that type of bone

A

Woven bone to Lamellar Bone

42
Q

What type of cells are involved in angiogenesis? What are they activated by?

A

Epithelial cells activated by VEGF

43
Q

process of forming new blood vessels

A

angiogenesis

44
Q

membranes, growth factors, substrates, and stem cells are ways to do what?

A

guided tissue regeneration

45
Q

types of procedures that can benefit from guided tissue regeneration

A

extractions, periodontal regeneration, and implant placement

Wound Healing (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions