Wound Healing

Question 1

Wound healing is an intericate coordinate series of processes that involve?

And it leadds to the release of?

Answer 1

Cellular and subcellular response
Cytokines and growth factors

Question 2

Acute wounds has?

Answer 2

Surgical traumatic, pathological, ischemic causes

Question 3

Intentionally created in the operating room environment

Answer 3

Surgical wounds

Question 4

caused by blunt or penetrating trauma result in tissue laceration, abrasion, or even tissue avulsion

Answer 4

Traumatic injuries

Question 5

When the tissue’s normal healing process experiences a disruption or delay, a ______ wound forms.

Answer 5

chronic

Question 6

Begins at the time of injury and lasts for 3 to 5 days.

Answer 6

INFLAMMATORY PHASE

Question 7

Normal wound healing results in tissue regeneration and takes place in three separate but overlapping phases

Answer 7

Inflammation, proliferation, remodelling

Question 8

Inflammatory phase begins at? And last for?

Answer 8

time of injury and lasts for 3 to 5 days.

Question 9

What initiates the process of inflammatory phase?

Answer 9

Vasoconstriction

Question 10

_____,_____ cause small blood vessels to constrict for initial hemostasis.

Answer 10

catecholamines and prostaglandins

Question 11

When platelets adhere to the exposed subendothelial collagen of injured vessels with the aid of von Willebrand factor, they degranulate, releasing

Answer 11

adenosine triphosphate, serotonin, prostaglandins, and thromboxane A2.

Question 12

Fourth or fifth day and last 2 to 3 weeks

Answer 12

Proliferative phase

Question 13

Characterized by the ingrowth and proliferation of granulation tissue within the wound

Answer 13

PROLIFERATIVE PHASE

Question 14

Proliferative phase start at____ day and last ___ to___ weeks

Answer 14

Fourthh or fifth, 2-3 weeks

Question 15

Actively produce proteoglycans and collagen, with force, stress, strain, and motion directing the collagen and proteoglycan alignment

Answer 15

Fibroplasia

Question 16

Crucial part of healing

new vasculature is required for the influx of oxygen and nutrients and the removal of metabolic waste products

Answer 16

Angiogenesis

Question 17

Epithelialization three phases

Answer 17

Epithelial migration, proliferation and differentiation

Question 18

Tissue remodeling finalizes the wound healing process

Characterized by an increase in wound tensile strength related to increased collagen production and breakdown

Answer 18

MATURATION

Question 19

Begins after the third week and usually lasts 6 to 12 months

Answer 19

MATURATION

Question 20

Maturation phase begins at the _____ week and usually last ___ to___ months

Answer 20

Third week, 6-12 months

Question 21

Abnormal Soft Tissue Healing (Repair)

Clinically similar, they differ in their formative timeline and boundaries

Answer 21

KELOIDS AND HYPERTROPHIC SCARS

Question 22

TYPES OF WOUND HEALING

Answer 22

PRIMARY INTENTION SECONDARY INTENTION TERTIARY INTENTION

Question 23

Healing by ________ occurs in wounds with dermal edges that are close together (e.g a scalpel incision).

It is usually faster than by secondary intention, and occurs in four stages

Answer 23

primary intention

Question 24

Healing by _______ occurs when the sides of the wound are not opposed, therefore healing must occur from the bottom of the wound upwards.

Answer 24

secondary intention

Question 25

An uncommon complication from wound healing (particularly in people with darker skin), are keloid scars, whereby there is excessive collagen production, leading to extensive scarring. This can occur in both primary and secondary intention healing.

Answer 25

SECONDARY HEALING INTENTION

Question 26

is delayed primary wound healing after 4–6 days. This occurs when the process of secondary intention is intentionally interrupted and the wound is mechanically closed.

Answer 26

TERTIARY HEALING INTENTION

Question 27

the action of platelets and cytokines forms a haematoma and causes vasoconstriction, limiting blood loss at the affected area

Answer 27

Haemostasis

Question 28

a cellular inflammatory response acts to remove any cell debris and pathogens present

Answer 28

Inflammation

Question 29

cytokines released by inflammatory cells drive the proliferation of the fibroblasts and the formation of granulation tissue

Answer 29

Proliferation

Question 30

collagen fibres are deposited within the wound to provide strength in the region, with the fibroblasts subsequently undergoing apoptosis

Answer 30

Remodelling

Question 31

located between the ramus of the mandible and the ear, and deep to the muscles in that area

Answer 31

Parotid

Question 32

located in the posterior area of the floor of the mouth, beneath the mylohyoid muscle

Answer 32

Submandibular

Question 33

located in the anterior area of the floor of the mouth, above the mylohyoid muscle

Answer 33

Sublingual

Question 34

MAJOR SALIVARY GLANDS

Answer 34

Parotid,submandibular,sublingual

Question 35

The parotid gland secretes saliva into the oral cavity via

Answer 35

Stensens duct

Question 36

The submandibular gland secretes saliva into the floor of the mouth via

Answer 36

Whartons duct

Question 37

The sublingual gland secretes saliva into the floor of the mouth via

Answer 37

Bartholin’s duct

Question 38

Largest salivary gland

Answer 38

Parotid gland

Question 39

Situated in the posterior part of the floor of the mouth, adjacent to the medial aspect of the mandible and wrapping around the posterior border of the mylohyoid muscle

Answer 39

Submandibular gland

Question 40

Submandibular blood supply and parasympathetic nerve supply?

Answer 40

Facial and lingual arteries CN VII- vestibulocochlear nerve

Question 41

Smallest of the paired major salivary glands Located in the anterior part of the floor of the mouth between the mucosa and the mylohyoid muscle

Answer 41

SUBLINGUAL GLAND

Question 42

Sublingual. Blood supply and parasympathetic innervation?

Answer 42

Sublingual and submental A. CNII-facial nerve

Question 43

The major salivary gland begin development in the embryo at around the ___

Answer 43

seventh week

Question 44

The parotid glands begin to develop at ___ to___ week of embryonic life

Answer 44

4 to 6

Question 45

The submandibular glands begin to develop at ___ weeks

Answer 45

6 weeks

Question 46

The Sublingual and minor salivary glands at ___ to ___ weeks

Answer 46

8-12 weeks

Question 47

difficulty in eating, speaking, and swallowing, prone to mucosal infections and rampant caries

Answer 47

Xerostomia

Question 48

Complex fluid

Answer 48

SALIVA

Question 49

SECRETORY CELLS

Answer 49

Serous cells, Mucous cells

Question 50

Serous cells:

Answer 50

Proteins and glycoproteins Enzymatic, antimicrobial, calcium binding activities

Question 51

Mucous cells

Answer 51

Mucin (apomucin) Lubricate and form a barrier on surfaces and to bind and aggregate microorganism

Question 52

Parotid gland blood supply and parasympathetic nerve supply?

Answer 52

External carotid A, Glossopharyngeal N