Workup/Staging Flashcards
What is the workup for penile cancer?
Penile cancer workup: H&P, basic labs, Bx, MRI or US of penis to assess DOI. CT, MRI, or PET/CT to assess nodes in pts with high BMI, prior inguinal procedures, or palpable inguinal adenopathy.
What is the AJCC 8th edition (2017) T staging for penile cancer?
Tis: CIS only (aka PeIN)
Ta: noninvasive localized SCC
T1: Glans: tumor invades lamina propria
Foreskin: invades dermis, lamina propria, or dartos fascia
Shaft: invades connective tissue b/t epidermis and corpora regardless of location
T1a: grade 1–2, without LVI or PNI
T1b: either LVI, PNI, or grade 3
T2: invades corpora spongiosum (either glans or ventral shaft) with or without urethral invasion
T3: invades corpora cavernosum (including tunica albuginea) with or without urethral invasion
T4: invades into adjacent structures (i.e., scrotum, prostate, pubic bone)
What is the AJCC 8th edition (2017) clinical and pathologic N staging for penile cancer?
cN1: single palpable mobile unilat inguinal LN
cN2: multiple palpable mobile inguinal LNs or bilat inguinal LNs
cN3: palpable fixed inguinal nodal mass or pelvic LNs
pN1: ≤2 unilat inguinal LNs, no ENE
pN2: ≥3 unilat or bilat inguinal LNs
pN3: inguinal LNs with ENE or pelvic LNs
What is the AJCC 8th edition (2017) stage grouping for penile cancer?
Stage I: T1a, N0, M0
Stage IIA: T1b–T2, N0, M0
Stage IIB: T3, N0, M0
Stage IIIA: T1–3, N1, M0
Stage IIIB: T1–3, N2, M0
Stage IV: T4, N3 or M1
