Workup/Staging Flashcards

1
Q

What is the workup for pts with suspected OPG?

A

Suspected OPG workup: H&P (including a neuro-ophthalmic exam with a quantitative visual acuity assessment), MRI brain and orbits, genetic evaluation, and baseline endocrinology

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2
Q

What is the DDx of an optic nerve mass?

A

Optic neuritis, glioma, RB, optic nerve meningioma, lymphoma, hamartoma

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3
Q

How do OPGs appear on MRI?

A

On MRI, OPGs appear as well-circumscribed, homogeneously enhancing lesions (isointense on T1 and iso- to hyperintense on T2). Contrast enhancement and presence of cysts are more common in sporadic OPGs than in NF-1 associated.

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4
Q

Is Bx necessary for Dx?

A

No. Imaging and the clinical exam are sufficient for OPG Dx.

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