Work-up & Staging Flashcards
What type of workup is necessary?
LCH workup: H&P, labs, skeletal survey (lucency in the medullary cavity), and Bx
What is the appearance of LCH lesions on plain radiograph?
LCH lesions appear lytic or “punched-out” on plain radiograph.
What other radiographic studies are useful?
PET scan has been found to be the most sensitive test. Bone can be used in conjunction with skeletal survey if PET is not available.
What staging system is used for LCH?
A staging system was proposed by Greenberg et al. in 1981, but is not universally accepted. The Histiocyte Society guidelines describe a 2-system stratification. Single system: 1 organ or system involved or Multisystem: 2 or more organs/systems involved.