Woo Midterm Flashcards

1
Q

Wakefields definition of psychopathology

A

psychopathology is a harmful dysfunction.

  1. harmful: a value judgment (what we consider to be harmful is socially constructed. this may change over time (e.g. male aggressiveness as necessary is now seen as harmful)
  2. dysfunction: failure of internal mechanisms to perform naturally selected functions (evolutionary theory)
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2
Q

What is a symptom?

A

experienced subjectively and reported by client (e.g. hallucinations)

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3
Q

whats the difference between a symptom, syndrome, and sign?

A
  1. symptoms: experienced subjectively and reported by client (e.g. hallucinations)
  2. signs: can be observed and documented objectively (e.g. agitation, crying, psychomotor retardation)
  3. syndrome: a cluster of signs and symptoms
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4
Q

ways in which culture can affect the manifestation of psychopathology

A
  1. psychiatric dx is an INTERPRETATION of a person’s experience
  2. they are concepts - not diseases (invented)
  3. interpretations of distress may be different depending on client’s background/tx provider
  4. language used to describe emotional difficulties (e.g. emotional or mental problem)
  5. what symptoms and signs of a syndrome are prominent or commonly reported (ex: PTSD)
  6. what approaches will be used to treat or deal w/ the problem (e.g. delays in help seeing among asian americans due to stigma might result in coming w/ more severe symptoms)
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5
Q

universalist approach to the question regarding manifestation of psychopathology across cultures (what are the basic tenets and assumptions?)

A

universal, see around the world, signs/clusters of syndromes with specific manifestations. basically, disorder are found everywhere, same symptoms occur no matter where you look. that said, teh manifestation of that disorder and the threshold varies between cultures.

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6
Q

relativistic approach to the manifestation of psychopathology across cultures? (basic tenets and and assumptions?)

A

culture shapes everything so on Dx system is not best, we may miss important disorders by trying to make them fit in the DSM and look homogeneous (Ex ataque de nervios and anxiety disorders). Depends on the disorder, some have evidence for a universal component (Schizophrenia) but different content in delusions.
-“there are certain groups of symptoms that we see only in certain environments. in some cases there are culture bound symptoms, that if missed, are confused for being same or mistake definition of symptoms mean same thing to different cultures

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7
Q

What is Emic versus etic perspective?

A

Emic and etic are terms used by anthropologists and by others in the social and behavioral sciences to refer to two kinds of data concerning human behavior. In particular, they are used in cultural anthropology to refer to kinds of fieldwork done and viewpoints obtained

  • An ‘emic’ account is a description of behavior or a belief in terms meaningful (consciously or unconsciously) to the actor; that is, an emic account comes from a person within the culture. Almost anything from within a culture can provide an emic account.
  • An ‘etic’ account is a description of a behavior or belief by an observer, in terms that can be applied to other cultures; that is, an etic account attempts to be ‘culturally neutral’.
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8
Q

What are the ways in which DSM tries to address cultural/ethnic diversity issues?

A

o for each clinical condition there is a “specific culture, age, and gender features section” that identifies variations in clinical presentation that can be affected by cultural or lifespan considerations
o provides information on differential prevalence rates related to culture/gender/age
o provides an outline for cultural formulation highlighting factors to consider in assessing clients from diverse cultural backgrounds

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9
Q

what is the dsmIV outline for cultural formulation?

A

cultural identity of individual
cultural explanations for illness
cultural factors related to teh psychosocial environment and level of functioning
cultural elements of the relationship between the individual and clinician

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10
Q

what is a syndrome?

A

a cluster of signs and symptoms

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11
Q

what is a sign?

A

can be observed and documented objectively (e.g. agitation, crying, psychomotor retardation)

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12
Q

what does culture influence?

A

the language used to describe the emotional difficulties, whether an experience is even conceptualized as an emotional or mental problem, what symptoms/signs of a syndrome are prominent of commonly reported, and what approaches will be used to treat ordeal with the problem? (ex is help seeking behaviors among asian clients due to stigma concerns)

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13
Q

Diversity/Special Considerations for assessing children and older adults:

A

for age: think of language abilities between kids and adults
ex: social phobia presents differently in kids versus adults, things like depression and dementia are frequently confused in older adults, and gender can come in to play (like how women are more often diagnosed with depression or autism in boys)

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14
Q

Monotheistic criteria sets? (include advantages and disadvantages)

A

this requires that each one of several diagnostic criteria have to be present in order to make a diagnosis; hence, the criteria are jointly necessary and sufficient. thus, before a diagnosis of depersonalization disorder can be assigned, all four diagnostic criteria must be met. this approach works best when disorders are homogeneous: in relation to their defining features, each category is mutually exclusive and the boundaries distinguishing different disorders are all clear. it tends to increase the reliability of diagnosis, but at teh expense of validity and clinical utility. it also runs the risk of reifying diagnostic categories and reduces the need for clinical judgment or inferences.

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15
Q

polytheistic criteria sets (include advantages and disadvantages)

A

need a list/subset of Dx criteria (Ex 5/9 of the following symptoms…)
this approach involves many possible signs or symptoms as diagnostic criteria. this format lists a range of symptoms and signs, not all of which are required for a diagnosis; an individual may be assigned diagnosis based on a subset of possible idagnostic features that were sufficient to meet the diagnostic threshold. this organization allows for more open diagnostic system that can accountfor the natural heterogeneity of psychiatric disorders. unfortunately, it increases the complexity and heterogeneity of the diagnostic categories.

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16
Q

what are the major models of psychopathology? (7 of them)

A
psychodynamic
behavioral
cognitive
humanistic/existential
systems/sociocultural
neurobiological
sociobiological/evolutionary
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17
Q

what does the behavioral approach emphasize?

A

role of learning principles in the maintenance of problem behavior or absence of adaptive behaviors (social learning theory, modeling). Every behavior serves a purpose or is being reinforced
• ex phobia as result of conditioning experience, depression as result of loss of reinforcement in one’s environment
• influence of modeling on behavior has implications for treatment (that we can model for our clients)

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18
Q

what does the psychodynamic approach emphasize?

A

unconscious drives/conflict are the basis for psychopathology, fixation or arrest at different developmental stages, defense mechanisms to deal with anxiety or other negative emotional states, quality of early relationships with caregivers
• Conflict within 3 parts of psyche (id/ego/superego)
• Ex. Dependent personality disorder: rely excessively on others due to problem in oral stage where over indulged and cannot resolve independence/dependence issue
• In the DSM: defensive functioning scale, a nod to psychodynamic theory

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19
Q

what does the cognitive approach emphasize?

A

psychopathology in terms of illogical, inaccurate cognitive schemas that dominate an individual’s thinking and ways of processing information
• distorted thought processes are associated with negative affective states that can effect one’s behaviors
• think of depression and Beck or anxiety disorders. Where thoughts, feelings, and behaviors all intervene in a triangle. We intervene with behaviors or thoughts, which lead to changes in feelings.

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20
Q

what does the humanistic/existential approach emphasize?

A

emphasis on free will and search for meaning,
• psychopathology from the inability to exercise free will, mastery in one’s life, experiences that call into question the fundamental assumptions about oneself and the nature of the world, inability to satisfy hierarchy of needs.
• Downplays emphasis on mental illness or diagnosis
• Unconditional positive regard, empathy, genuineness seen as necessary therapeutic elements.

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21
Q

what does the systems/sociocultural approach emphasize?

A

psychopathology must be understood in the wider social, interpersonal context in which it exists. Family and other social relationships affect individual behavior; each member of the system influences and is influenced by others in the system.
• DSM doesn’t reflect this very well, mostly V Codes
• Ex. Behavioral couples therapy for alcoholism, Minuchin and family dynamics in anorexia (families in anorexics are usually ridig, overprotective, etc)
• Counterproductive to focus solely on IP

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22
Q

what does the neurobiological approach emphasize?

A

emphasize the role of psychopathology from genetic factors, neurochemical abnormalities, impact of illness, injury, disease on brain function
• Even disorders that appear to have a strong psychosocial component involve the interplay of biological factors, like ptsd (where studies found high resting heartbeat is tied to increased likelihood of development)
• Some disorders in dsm like at border of neurology and psychiatry
• Ex. Dementia, Tic disorders

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23
Q

what does the sociobiological/evolutionary biological approach emphasize?

A

assumes that psychological phenomena occur as result of being evolutionary adaptive and maintained through natural selection
• ex. Anxiety as attention to physical dangers…now maladaptive in todays world
• however, in some cases, these phenomena may be maladaptive by today’s standards (ex biological preparedness and phobias)

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24
Q

describe maslow’s hierarchy of needs

A

-physiological (breathing, food, sex, sleep, water
-safety: security of body, employment, resources, morality, family, health, property
Love/Belongingness: friendship, family, sexual intimacy
Esteem: self-esteem confidence, achievement, respect of and by others

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25
Q

Biopsychosocial model

A

emphasizes the interplay of biologiocal, psychological, and social factors in understanding mental disorders. Like the diathesis-stress model of psychopathology. With diathesis being the biological or genetic predisposition, and the environmental events or stressors triggering the disorder.

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26
Q

define developmental path. term: equifinality

A

There are multiple paths to psychopathology east. disparate routes may lead to a common outcome. all roads lead to rome in that different factors can lead to same outcome

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27
Q

define development term: multifinality

A

a given risk factor or initial state can lead to disparate outcomes during the course of development across different individuals.

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28
Q

how is substance dependence different than abuse?

A

dependence involves physiological symptoms of tolerance and withdrawal or psychological perception that they need substance to feel ok or function optimally, and is characterized by addiction and impaired control.
abuse is a maladaptive pattern and dependence criteria have never been met and is characterized by denial and limited control.

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29
Q

what is tolerance?

A

celular and metabolic adaptations in response to continued presence of substance. more is needed to achieve same effect, use becomes more frequent, and cross tolerance.

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30
Q

what is withdrawal?

A
  • experienced when administration of a substance to dependent individual is stopped/greatly reduced.
  • characteristic withdrawal syndromes associated with different drugs
  • withdrawal sx tend to be opposite to effects produced by drugs.
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31
Q

are tolerance and withdrawal required for a dependence diagnosis?

A

yes: for dependence diagnosis, “physiological adaptation of the body to prolonged exposure to the substance. tow aspects of this adaptation is tolerance and withdrawal”
dependence specifiers: “with phsyiological dependence when tolderance or withdrawal is present”
“without physiological dependence when no evidence of tolerance or withdrawal, instead is pattern characterized by pattern of compulsive substance use”

32
Q

current problems with the abuse/dependence distinction in the dsm:

A

o Dependence creates confusion: ex physicians may equate tolerance and withdrawal as dependence, ex may lead to under-medication of pain patients who evidence tolerance and withdrawal
o Poor test-retest reliability with abuse diagnosis, abuse not always a prodromal phase of dependence
o Too easy to get abuse diagnosis? Only need one sx
o Diagnostic “orphans” that are somewhere between.
o “Substance use Disorder”: still avoids diagnostic use of “addiction” despite endorsement of term by professional groups

33
Q

Substance abuse dsm IV criteria

A
  1. maladaptive pattern of recurrent substance use leading to significant impairment/distress.
  2. 1 or more within 12 months:
    - failure to fill major role obligations
    • recurrent use in physically hazardous situations
    • recurrent substance related legal probe
    • continued use in spite of interpersonal problems
  3. DEPENDENCE criteria NEVER MET!!!
34
Q

Substance Dependence DsmIV criteria

A

tolerance, withdrawal upon cessation, taking more of substance over longer period of time, loss of time related to use, activities forsaken, continued use despite knowledge of consequences.
dependence includes psychological and physical (like tolerance and withdrawal)

35
Q

Problems with abuse/dependence distinction is DSM

A

o Dependence creates confusion: ex physicians may equate tolerance and withdrawal as dependence, ex may lead to under-medication of pain patients who evidence tolerance and withdrawal
o Poor test-retest reliability with abuse diagnosis, abuse not always a prodromal phase of dependence
o Too easy to get abuse diagnosis? Only need one sx
o Diagnostic “orphans” that are somewhere between.
o “Substance use Disorder”: still avoids diagnostic use of “addiction” despite endorsement of term by professional groups

36
Q

Neuroadaptation and implications for tolerance and withdrawal?

A

drugs stimulate reward centers in the brain. With repeated substance use a homeostatic process known as neuroadaptation occurs in the brain. Brain adapts to excessive dopamine by decreasing production of dopamine and sensitivity of receptors (explains tolerance). when ingestion of an abused substance suddenly stops, teh body is not able to rapidly revert back to the preuse production levels of neurotransmitters affected, so these decreased levels then trigger withdrawal symptoms.

37
Q

What neurotransmitter is primarily implicated in substances of abuse?

A

usually drugs of abuse affect dopamine

38
Q

what are the basic tenets of substance use disorders related to psychodynamic approach?

A
  1. psychodynamic has the self medication hypothesis
    • substances may be used to ameliorate undifferentiated affected statues in alexythymic individuals
      • substances may be chosen for specific effects (like a heroin user has deep seated anger)
  2. serious psychopathology typically underlines substance use
39
Q

what are the basic tenets of substance use disorders related to behavioral approach?

A
  1. Classical conditioning: cravings (neutral S paired with UR leads to CS)
  2. operant conditioning (immediate positive reinforcement vs delayed punishment, withdrawal and continued use maintained by negative reinforcement)
    3, modeling (like teens seeing other teens drinking and then doing it themselves)
40
Q

what are the basic tenets of substance use disorders related to cognitive approach

A
  1. beliefs that facilitate use
  2. the role of self-efficacy related beliefs

they have:

  1. anticipatory beliefs (ill be productive if i use)
  2. relief oriented beliefs (my cravings will go away)
  3. facilitative/permissive beliefs (i deserce a reward: life is about taking risks sometimes
41
Q

what are the basic tenets of substance use disorders related to family based approach?

A

among adolescents, greater alcohol and drug use and poorer recovery are associated with variables such as”

  1. decreased parental involvement and monitoring
  2. parental displays of hostility and lack of warmth
    3. low family cohesion/higher rates of family conflict
    4. parental substance use is a risk factor for substance use in kids. (may be genetic or be due to modeling those behaviors or facilitating beliefs that make it acceptable)
42
Q

Legha et al article: how did these researchers make substance abuse treatment culturally responsive for a native american/alaskan native population?

A

Objective: Culture figures prominently in discussions regarding the etiology of alcohol and substance abuse in American Indian and Alaska Native (AI/AN) communities, and a substantial body of literature suggests that it is critical to developing meaningful treatment interventions. However, no study has characterized how programs integrate culture into their services. Furthermore, reports regarding the associated challenges are limited.
METHODS:Twenty key informant interviews with administrators and 15 focus groups with clinicians were conducted in 18 alcohol and substance abuse treatment programs serving AI/AN communities. Transcripts were coded to identify relevant themes.
RESULTS:
Substance abuse treatment programs for AI/AN communities are integrating culture into their services in two discrete ways: by implementing specific cultural practices and by adapting Western treatment models. More important, however, are the fundamental principles that shape these programs and their interactions with the people and communities they serve. These foundational beliefs and values, defined in this study as the core cultural constructs that validate and incorporate AI/AN experience and world view, include an emphasis on community and family, meaningful relationships with and respect for clients, a homelike atmosphere within the program setting, and an “open door” policy for clients. The primary challenges for integrating these cultural practices include AI/AN communities’ cultural diversity and limited socioeconomic resources to design and implement these practices.
CONCLUSIONS:
The prominence of foundational beliefs and values is striking and suggests a broader definition of culture when designing services. This definition of foundational beliefs and values should help other diverse communities culturally adapt their substance abuse interventions in more meaningful ways.

43
Q

The role of expectancies in substance use disorders?

A

: expectancy refers to use and ability to stop using. Studied mostly in alcohol use and over time become more positive
o may form from direct experience or observation in others (family) and can change over time
o the faster one can call up an expectancy the greater the risk factor (if can call up a positive one before a negative one)
o with cocaine over time expectancies become more negative
o interact with personality and emotional traits to predict substance use. Ex: impulsive= more positive expectancies around drug use. Negative affect or strssors to extent think drinking will increase mood
(like people with impulsivity tend to have positive expectancies regarding SU)

44
Q

What are the 4 principles upon which MI is based?

A

o 1.) Expression of Empathy: active listening, reflection, normalize
o 2.) Develop Discrepancy: amplify where someone is currently and where they want to be
o 3.) Roll with Resistance: a process between therapist and client
• amplified reflections, double sided reflections (refer back to previous statement after reflecting back what was just said), coming alongside (agreeing with someone), rule questions
o 4.) Support Self-Efficacy: instill belief that they are capable and responsible for change

45
Q

what are the theoretical underpinnings of MI?

A

MI was developed by miller and rollick, and was influenced by prochaska and DiClemente’s Stages of Change model.
“enhancing intrinsic motivation to change client centered, directive method by exploring and resolving ambivalence”

46
Q

what are the stages of change influencing techniques of MI?

A
  1. precontemplation (psychoeducation)
  2. contemplation (resolve ambivalence)
  3. preparation (process the emotional. logistic, and social aspects of change)
  4. Action (teach coping to help with behavioral change, learn new bxs,)
  5. Maintenance (continue teaching and reinforcing relapse prevention strategies)
47
Q

What are the General goals of relapse prevention in MI?

A

relapse prevention provides a way of assessing full range of antecedents and consequences of use that may influence relapse potential and selecting interventions to help clients avoid/deal with risky situations in ways that reduce probability of a relapse.
prevent relapse in sobriety and maintain goals related to abstinence or hard reduction, teach tools to manage lapse (should it occur) and to prevent further relapse, coping skills training as cornerstone

48
Q

define analysis of past relapses

A

step by step by account of when someone last used. asked in great detail what happened to help them identify triggers/patterns/antecedents. also show them how these small choices lead to relapse

49
Q

define relapse fantasies

A

what would it take for your to start using again?

50
Q

define abstinence violation effect (AVE)

A

The idea that if they lapse, they relapse and are a drinker. here you want to show them that just bc they lapsed once didn’t mean they are back to being an alcoholic. it refers to the constellation of cognitive and affective experiences that typically follow a lapse. mean attribute violation of abstinence to internal, global, stable factors (lack of will power or underlying addiction or disease)→if attribute to an unstable, unusual situation, less likely to relapse

51
Q

define apparently irrelevant decisions (AIDS)

A

go blow by blow of account to look at small decisions

52
Q

define positive outcome expectancies

A

PIG= problem of immediate gratification, cost of impulsive consumption

53
Q

what are basic tenets and strategies used in behavioral couples therapy for alcoholism?

A

12-20 conjoint sessions, focuses on couple engagement, supporting abstinence, relational-focus, and continuing recovery.
o Goal is to stabilize alcohol problem and alter general marital and family patterns to provide an atmosphere conducive to sobriety
o Interventions: behavioral contracts (sobriety contract, sobriety calendar), determination of behaviors that reinforce or enable partner’s drinking, dealing with relapse in treatment
o Interventions to improve relationship: increase positive behavior exchange (catch partner doing something nice, planned leisure activities), communication training (speaker/listener), make positive specific requests, negotiation and compromise, problem solving skills
o Those who benefit: have a high school degree, employed or want to work, couple is still living together, enter therapy in a crisis, alcohol problems of longer duration
o Less likely to benefit: psychosis, severe violence, both alcoholic

54
Q

what are some ways to id high risk situations in terms of Relapse prevention in MI?

A

client autobiography, analysis of past relapses, relapse fantasies, and self-monitoring

55
Q

what are general principles of the 12 step program?

A
abstinence based (AA), view alcoholism as a disease and not bad behavior
o	recovery coming from connecting to something bigger than oneself, paradox of surrounding power so as to ultimately be empowered to gain sobriety, interpersonal support is critical to recovery, recovery viewed as a lifelong process with continued personal growth
o	not moderated or lead by mental health professional but by members themselves, during closed meetings individuals share their stories about problems and struggles with alcohol and how they are trying to maintain sobriety, differences in how “higher power” is defined, sponsorship is important part of the tradition
56
Q

is there evidence that a 12 step program works?

A

YES!

  • AA + professional treatment⇒ greater remission rates than professional treatment alone
  • AA participation associated with improved social support resources, less avoidant coping, less likelihood of drinking as a coping mechanism
  • sponsorship and service participation especially important elements in predicting abstinence
  • do people in AA do better because it attracts people already likely to succeed in treatment? One study says no.
57
Q

what did project MATCH find regarding 12-step interventions (slides and chapter info)

A

notes: • AA particularly helpful for patients who have a support system that encouraged drinking and were recent inpatients highly dependent on alcohol
• May not be as helpful for alcohol dependent individuals angry at start of treatment
• Lack of religiosity should not be a factor discouraging involvement with AA
Book: match was a unique multisite study that investigated whether it was posible to develop guidelines for matching clients with alcohol use disorders to appropriate treatment modalities based on client characteristics. (CBT, motivational enhancement, and 12 step facilitation therapy were used) findings said no one group better than others, but instead people who have social support sytems likely to support drinking do better in AA, people with high dependence on alcohol likely to better in 12 step program, and individuals who are angry at start are better in motivational enhancement

58
Q

Describe the characteristics of atypical depression

A

characterized by mood reactivity—being able to experience improved mood in response to positive events. Atypical features are much more common in bipolar disorders and they respond differently to meds (better with MAOis)

59
Q

Describe the characteristics of melancholic depression

A

characterized by anhedonia (the inability to find pleasure in positive things), or lack of mood reactivity (i.e. mood does not improve in response to positive events) and at least 3: a quality of depressed mood more pronounced than that of grief or loss, a worsening of symptoms in the morning hours, early-morning waking, psychomotor retardation, excessive weight loss
a severe form of depression that responds to somatic treatments (antidepressants, ECT; poor placebo response).
book says: experience a loss of pleasure in all or almost all activities and are nonreactive to usually pleasureable activities, must display 3/6 symptoms, and is severe.

60
Q

Describe the characteristics of chronic depression

A

Meets criteria continuously

61
Q

diagnostic criteria for MDD

A

requires one or more more depressive episodes, no history of mood episodes that would indicate bipolar disorder (no manic, hypomanic or mixed), and no symptoms that would indicate another disorder like schizoaffective disorder
MDE reqmts: an individual must experience sx for most days, nearly everyday for a minimum of 2 weeks.

There must be sad mood and/or anhedonia. If one or the other is present, an additional 4 sx from the above list are needed.

Anhedonia: Cognitive factors can underlie the lack of interest in activities and the attendant behavioral inhibition seen in depression. This includes beliefs like “I won’t be able to do anything” and beliefs that doing anything won’t bring any pleasure anyways.

If there are BOTH sad mood and anhedonia, only 3 additional sx are needed. (5 total sx are needed).

MDE criteria are on page 356 of DSM-IV-TR. Sx can be grouped into:

Emotional sx: depressed mood

Vegetative sx : appetite/weight disturbance (e.g., anorexia), sleep problems (e.g., insomnia, excessive sleep), fatigue, psychomotor disturbance, and impaired attention.
Rule of thumb for weight gain is 5%
Agitation or retardation must be observable by others.
Loss of ability to perform in school may be a sign of depression in children.
In some older adults, a depressive episode with memory difficulties occurs in the early phase of an evolving dementia.

Cognitive symptoms: feelings of worthlessness, guilt; difficulties with concentration; suicidal thoughts

Suicidal thoughts, actions (note that these are described as needing to be recurrent thoughts – so not necessarily occurring most days – or a single attempt (“an attempt or a specific plan”). This is in contrast to other dep sx that are specified as needing to be present everyday or nearly everyday.

62
Q

Diagnostic criteria for Dysthymia?

A

Chronic depression (2 yrs adults, 1 kids),
accompanied by: 2/6 symptoms of depression
during 2 year period, no sx remission for more than 2 mod at a time
no MDE during first 2 yrs of disorder
no manic or hypomanic episodes
(*75-90% with dysthymia report hx of md at some time during their illnessm and children with dysthymia, 42%-75% have superimposed MDD aka double depression)
• Double depression involves having dysthymia for at least two years before a having a Major depressive episode.,

63
Q

how do MDD and Dysthymia differ?

A
  • MDD involves one or more major depressive episodes (MDE) with no history of manic hypomanic or mixed episodes
  • Dysthymia involves chronic depression for at least 2 years (one year for child) and depressed mood DOES NOT meat criteria for an MDE (though MDE can be superimposed after two years for double depression)

accompanied by 2 or 6 symptoms of depression without remission for 2 months and no MDE during the 1st two years of the disorder + no manic or hypomanic episodes.

Differences between major depressive disorder and dysthymia are characterized by levels of severity, duration and persistence. For example, the change in mood in major depression occurs nearly every day during a period of two weeks, whereas in dysthymia, the mood disturbance occurs more days than not during a two-year period. Dysthymia may be reported less than major depression, as its symptoms are less severe and easier to live with.

64
Q

What is the typical course of MDD and dysthymia?

A

• Over lifetime, one MDE is assoiciated with 50% chance of a second MDE
• Two MDEs associated with 70-80% chance of recurrance
• 20-25% experience only partial recovery between episodes
• 25% of individuals experience double depression
-median age for getting dep 23-25,and left untreated can lest 6-12 months.
In birth cohorts since the 1940s the prevalence of mood disorders has been increasing and the age of illness onset decreasing, leading some to dub this period the ‘‘age of melancholy’’. Causes remain unclear, but hypotheses range from changes in genetic loading for disorders across generations to the breakdown of societal supports and stressors associated with changes in social roles
By 2020, depression will be 2nd leading cause of disability worldwide
Affects 14 million American adults
Lifetime estimates – women: 5-9%; men: 2-3%
Point prevalence for adolescents: 4.7%
Rates of MDD have been found to range from 1-8% among older adults.
15% of individuals with MDD who attempt suicide will succeed in killing themselves
Individuals with MDD admitted to nursing homes have a 59% greater chance of death w/in 1st year

First and Tasman note that the presentation of a clinical depression can be highly variable – some will experience the stereotypical sadness as one of the most prominent symptoms, but others will primarily experience internal agitation and a generally uncomfortable mood. Still others will be primarily agitated, or will experience deep psychological pain that is not necessarily accompanied by marked sadness.

In adolescents an early sign of depression may be the presence of anxiety. (Note that brain changes that control emotions – frontal lobes (prefrontal cortex) – do not fully develop until mid 20’s).

65
Q

What is Double Depression?

A

• Double depression involves having dysthymia for at least two years BEFORE a having a Major depressive episode. dysthymic disorder is comorbid with MDD.

66
Q

What differences are observed between major depressive episodes in MDD versus bipolar disorder?

A

MDD: presence of at least one MDE but NO HIROTY OF MANIC< HYPOMAN< or MIXED EPISODES.
Bipolar: history of at least one manic/mixed/episode or • MDD – Insomnia, Agitated psychomotor activity, more somatic complaints
• Bipolar – Hypersomnia, psychomotor retardation, fewer somatic complaints

67
Q

What are characteristics of depression in older adults?

A

• Less likely to report dysphoria
• Commonly experience depletion syndrome (Loss of interest, loss of energy, psychomotor retardation, hopelessness, helplessness)
• Vascular depression: A form of late onset depression associated with vascular risk factors, cognitive impairment, psychomotor retardation, apathy
Also, sometimes depression looks like dimentia.

68
Q

What is the current bereavement exclusion for Major Depressive Disorder? (MDD)

A

Symptoms of a MDE are better accounted for by v-code of Bereavement unless the following are present:

marked functional impairment
morbid preoccupation with worthlessness
suicidal ideation
psychomotor retardation.
psychotic symptoms

Or MDE symptoms persist beyond 2 months

69
Q

Diversity Considerations for MDD and Bipolar Disorder?

A

• High rates of misdiagnosis among ethnic minorities - hispanics and african americans at most

70
Q

Medications commonly used for depressive disorders and potential problems for each

A
  • SSRIs – Most widely used, especially good for mild to moderate depression, sexual side effects, black box warning regarding suicide inyouth
  • Tricyclics – 2nd line treatments, as effective as SSRIs but worse side effects and overdose potential
  • MAOis – Effective for atypical depression, risk of hypertensive crisis if tyramine containing food is eaten (must monitor blood levels)
  • SNRIs
71
Q

Basic structure and findings of the STAR-D study?

A

largest prospective trial of MDD, plus they used real world individuals, and did several options.
1. all started on ssri citalopram,
after 12 wks, participated in a sequence of up to 3 random trials after
2.
remission rate found to take at least 8 weeks, sociodemographic measures and symptom patters did NOT predict differential benefit for meds options.

FOUND: there was NO CLEAR MEDICATION WINNER for pts whose depression didn’t remit after one or more aggressive med trials. both switching and augmenting are reasonable if meds fail, and 2/3 of patients who initally fail meds will get better after 4 levels of tx. also CBT and CR seems to produce similar remission rates as drugs, people on two meds instead of one seemed ot improve faster.

72
Q

features of Psychodynamic theories of depression:

A

person experiences real or imagined loss, disruption in early mother-child relationship is one basis.

73
Q

features of behavioral theories of depression:

A

lewinsohns behavioral model says that a lack of response-contingent reinforcement in an individual’s environment can lead to depression. basically, the person doesn’t do enough sufficiently rewarding activities.

74
Q

features of CBT theories of depression:

A

such as beck, these primarily have focused on teh role that negative cognitions play in creating a vulnerability to depression and maintaining a depression state. basicaly how you perceive and interpret events in you environment shapes you mood and behavior. they make cognitive errors in processing info, like selective abstraction

75
Q

features of Seligman’s learned helplessness theories of depression

A

based on animal research where dogs exposed to inescapable shock didn’t try to escape subseqent shocks. Seligman belived that individuals who believe they are helpless to control negative situations in their lives are vulnerable to becoming depressed. later it was added they depressed people tend to attribute negative outcomes to internal stable factors.

76
Q

features of interpersonal theories of depression.

A

these emphasize impairments in social relationships can have on onset and perpetuation of depression. like coyne, sho said that individuals become depressed in response to interpersonal losses.