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Pharmacology > women's health drugs > Flashcards

women's health drugs Flashcards

1
Q

what estrogen does in the body?

A

-thickens lining of the uterus, preparing for possible implantation of fertilized egg
-influences how the body uses calcium
-helps maintain health blood cholesterol levels
-keeps vagina healthy
-prevents osteoporosis

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2
Q

what does progesterone do in the body?

A

-helps prepare uterus for implantation of fertilized egg and maintain for pregnancy
-regulate BP
-improves sleep and mood

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3
Q

hormone replacement therapy: estrogen use

A

treat menopausal symptoms (hot flashes, vaginal dryness)

-treat lowest dose and shortest duration possible

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4
Q

hormone replacement therapy: estrogen examples

A

-Estraderm transdermal system
-climara pro
- vaginal cream
-estring
-femring
-estrogel
-estrasorb
-permarin

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5
Q

hormone replacement therapy: estrogen forms

A

patch
ring
cream
pills

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6
Q

hormone replacement therapy: estrogen contraindications

A

-estrogen dependent cancer
-undiagnosed vaginal bleeding
-pregnancy
-active thromboembolic disorder
-hx of clotting disorders

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7
Q

hormone replacement therapy: estrogen side effects

A

HA
N/V
breast tenderness

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8
Q

hormone replacement therapy: estrogen adverse effects

A

BLOOD CLOT
chemical hepatitis
HTN
edema
fluid retention

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9
Q

hormone replacement therapy: estrogen interactions

A

-decrease activity of oral anticoagulants
-increase toxicity of TCAs

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10
Q

hormone replacement therapy: estrogen nursing considerations

A

-take smallest dose
-give oral dose with food
-teach importance of annual checkups

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11
Q

progestins: provera action

A

inhibits the secretion of pituitary gonadotropins which prevent follicular maturation and ovulation

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12
Q

progestins: provera trade/generic name

A

provera (medroxyprogesterone)

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13
Q

progestins: provera pregnancy category

A

D

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14
Q

progestins: provera indications

A

-amenorrhea
-dysfunctional uterine bleeding

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15
Q

progestins: provera contraindications

A

-undiagnosed vaginal bleed
-estrogen dependent cancer
-liver disease
-pregnancy
-DVT

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16
Q

progestins: provera black box warning

A

CV disease/demation prevention
increase risk of MI, stroke, DVT

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17
Q

progestins: provera side effects

A

N/V
HA
breast pain
fluid retention
amenorrhea
galactorrhea

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18
Q

progestins: provera adverse effects

A

DVT
optic neuritis
HTN
stroke MI
breast cancer
ovarian cancer
jaundice

19
Q

progestins: provera monitoring

A

-pap smear
-breast exam
-pelvic exam at baseline and every 12 months after
-lipid panel

20
Q

progestins: provera nursing considerations

A

-teach on required test
-s/s of DVT/PE
-schedule of what days in a month to take provera

21
Q

depo-provera action

A

inhibits the secretion of pituitary gonadotropins

22
Q

depo-provera trade/generic

A

depo-provera/medroxyprogesterone acetate

23
Q

depo-provera containdications

A

breast cancer
liver tumors
liver disease

24
Q

depo-provera side effects

A

irregular bleed
weight gain
decrease libido
HA
acne
alopecia

25
Q

depo-provera adverse effects

A

b.b warning for significant BMD loss, use only as long term birth control (>2 years) if other methods inadequate, DVT, angioedema, depression

26
Q

depo-provera monitoring

A

-bone density
-glucose levels if diabetic
-pregnancy test if >14 weeks between doses

27
Q

herbs for menopause: isoflavones

A

use night sweat, hot flashes

-plant based estrogens
-can be found in: soymilk, soybeans, tofu

28
Q

herbs for menopause: black cohash

A

used for hot flashes, night sweats, vaginal dryness

-side effect: GI upset

29
Q

herbs for menopause: evening primose

A

use for hot flashes

-side effects: N/D, decrease blood clots

30
Q

herbs for menopause: don quai

A

use for hot flashes and night sweats

-little research on this product

31
Q

oral contraceptives: estrogen progestin combo

monophasic

A

fixed estrogen-progestin combo

12-28 day

32
Q

oral contraceptives: estrogen progestin combo

biphasic

A

fixed estrogen, variable progestin

21-28 day

33
Q

oral contraceptives: estrogen progestin combo

triphasic

A

3 or 4 monthly with estrogen and progestin

21-28 day

34
Q

extended cycle oral contraceptives

A

120 days

35
Q

oral contraceptives: action

A

-prevents ovulation
-increase uterine mucous viscosity and inhibits implantation of ovum

36
Q

oral contraceptives: indications

A

-prevent pregnancy
-endometriosis
-hypermenorrhea
-post coital emergency contraception
-menstrual cycle irregularity
-functional ovarian cyst

37
Q

oral contraceptives: side effects

A

HA
migraine
N/V
breast tenderness

38
Q

oral contraceptives: adverse effects

A

HTN
DVT
PE
alteration in lipid and carbohydrate metabolism

39
Q

oral contraceptives: interactions

reduce effectiveness and need alternative

A

antibiotics
barbiturates
INH
rifampin
St. Johns Wort

40
Q

oral contraceptives: less effective

A

anticonvulsants
hyptonics
warfarin
BB
antidiabetic
theophylline
TCAs

41
Q

emergency contraception: `use

A

prevent pregnancy after sexual intercourse

42
Q

emergency contraception: action

A

prevent/delay ovulation

43
Q

emergency contraception: trade/generic name

A

plan B , take action

44
Q

emergency contraception: nursing considerations

A

-assess hx and meds
-smoker?
-pregnant?
-educate on proper use
-drug interactions
-condoms
-depo=loss of bone density

Pharmacology (5 decks)

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