Women's Health Flashcards

1
Q

Booking visit is at ________ weeks gestation. Ideally < ____ gestation.

A

8-12 weeks

Ideally < 10 weeks

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2
Q

What is checked at booking visit?

A

General info: lifestyle, folic acid, vitamin d, BMI.

Bloods:

  • FBC
  • Blood group + rhesus status
  • BBV: Hep B, Syphilis, HIV

Urine culture:
- For bacteriuria (e.g. GBS)

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3
Q

Early pregnancy scan to confirm dates is at ______ weeks gestation.

A

10 - 13+6 weeks

Down’s syndrome from 11 - 13+6 weeks

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4
Q

Anomaly scan is at ______ weeks gestation

A

18 - 20+6 weeks

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5
Q

When is first dose of anti-D prophylaxis given to rhesus negative women?

25 weeks
28 weeks
30 weeks
34 weeks

A

28 weeks

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6
Q

When is second dose of anti-D prophylaxis given to rhesus negative women?

25 weeks
28 weeks
30 weeks
34 weeks

A

34 weeks

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7
Q

External cephalic version is offered at ____ weeks gestation.

A

36 weeks

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8
Q

30F. Severe dysmenorrhoea, heavy & irregular bleeding, pain on defecation and dyspareunia. Likely diagnosis?

A

Endometriosis

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9
Q

20F. 1 week cramping and constant lower abdo pain, intermenstrual bleeding, dyspareunia + dysuria

A

PID

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10
Q

‘Snowstorm’ appearance on USS.

A

Hydatidiform mole (molar pregnancy)

  • Abnormal growth of cells in uterus. Type of gestational trophoblastic disease.
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11
Q

Mechanism of action of implant?

A

Inhibits ovulation and thickens cervical mucus

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12
Q

Mechanism of action of depot provera?

A

Inhibits ovulation and thickens cervical mucus

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13
Q

Mechanism of action of IUS?

A

Prevents endometrial proliferation

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14
Q

Levonorgestrel is in what contraception?

A

Mirena coil and Plan B emergency contraception (within 72 hours)

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15
Q

Medroxyprogesterone acetate is in what contraception?

A

Depot Provera

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16
Q

Etonogestrel is in what contraception?

A

Implant

17
Q

Cervical smear shows negative (high-risk) HPV - how should this person be managed?

  • Return to normal recall
  • Repeat in 3 months
  • Cytology
A

Return to normal recall. No need for cytology examination

18
Q

How to manage hrHPV positive and cytology normal smear?

A

Repeat smear in 12 months

19
Q

Repeat smear at 12 months for HPV positive + normal cytology shows HPV still positive…

A

Repeat smear in another 12 months

20
Q

HPV positive with normal cytology at 24 months

A

Refer to colposcopy

21
Q

First inadequate sample should be managed by _______.

Two inadequate samples should be managed by _______.

A

Repeat smear at 3 months

Refer to colposcopy if 2 consecutive inadequate smears.

22
Q

Contraceptives: time until effective?

Implant

A

After 7 days

23
Q

Contraceptives: time until effective?

Combined oral contraceptive pill

A

After 7 days

Unless taken within first 5 days of cycle - then covered

24
Q

Contraceptives: time until effective?

Depo Provera

A

After 7 days

25
Q

The placenta is attached to myometrium in placenta _______. This can cause PPH.

A

Accreta

26
Q

Strongest risk factor for cervical cancer?

A
  • HPV (16 & 18)
  • COCP
  • Many sexual partners
27
Q

Mutation of BRCA1 gene is a risk factor for what female cancers?

A

Ovarian and breast cancer

28
Q

Mechanism of action of COCP?

A

Inhibits ovulation

29
Q

How does HPV 16 cause cervical cancer?

A
  • Produces E6 oncogene

- This inhibits the p53 tumour suppressor gene

30
Q

How does HPV 18 cause cervical cancer?

A
  • Produces E7 oncogene

- This inhibits RB suppressor gene

31
Q

COCP counselling - what are the potential risks?

A

> 99% effective if take correctly

Risks:

  • Blood clots
  • MI and stroke
  • Breast and cervical cancer
32
Q

Endometrial cancer risk factors?

A
  • Obesity, DM, PCOS
  • Early menarche and late menopause
  • Nulliparity
  • Drugs: unopposed oestrogen (e.g. HRT), tamoxifen
33
Q

Investigation for endometrial cancer?

A
  1. Trans-vaginal ultrasound - to look at endometrial thickness
  2. Endometrial biopsy
34
Q

Management of endometrial cancer?

A

TAH + BSO

+/- post-operative RTX

35
Q

Mechanism of action of IUD?

A

Decreases sperm motility and survival