Women's Health

Question 1

MOA of bisphosphonates

Answer 1

inhibit osteoclast-mediated bone reabsorption –> enhances bone mineral density

Question 2

drugs that are bisphosphonates

Answer 2

alendtonate
ibandronate
risedronate
zoledronic acid

Question 3

adverse effects of bisphosphonates

Answer 3

HA, GI upset, joint pain

risk of esophageal burns if med lodges in esophagus before reaching stomach

risk of osteonecrosis of the jaw

possible severe bone, joint, or muscle pain

Question 4

patient teaching for bisphosphonates

Answer 4

take at least 30 min before the first morning beverage or food with at least 6-8 oz of water

need to remain upright for at least 30 min after taking the med to prevent esophageal and GI adverse effects

Question 5

adverse effects of oral contraceptives

Answer 5

HA, dizziness, breast tenderness, nausea, breakthrough bleeding, decreased libido, mood swings, weight gain

HTN
thromboembolism, possible PE, MI, stroke
alterations in lipid and carbohydrate metabolism
increases serum hormone concentrations
kidney stones
gallbladder problems

Question 6

drug interactions of oral contraceptives

Answer 6

antibiotics
barbiturates
isoniazid
rifampin
can decrease effectiveness of oral contraceptives