WM- What's in a Medicine?

Question 1

How do pharmaceutical companies assess the potential of compounds as medicines?

Answer 1

Combinatorial chemistry; makes many related compounds to test them for pharmacological activity

Question 2

What do the phase I trials establish?

Answer 2

SAFETY of the potential medicine

Question 3

What do phase II trials establish?

Answer 3

EFFECTIVENESS of the potential medicine

Question 4

What do phase III trials establish?

Answer 4

If the potential medicine is better than the standard treatment

Question 5

What is the strongest type of acid?

Answer 5

Carboxylic acid

Question 6

What is the weakest type of acid?

Answer 6

Alcohol

Question 7

True or false? Phenol is a weaker acid than water

Answer 7

False. Phenol is stronger than water in terms of acidity

Question 8

What defines the strength of an acid?

Answer 8

Delocalisation levels / ability to delocalise

Question 9

What happens when neutral iron (III) chloride is added to phenol and its derivatives?

Answer 9

A purple complex is formed

Question 10

What is combinatorial chemistry?

Answer 10

A method for synthesising a large number of analogues in a short time.