wk2 Flashcards
Motor neuron
Efferent neurone
Relays messages from the brain or spinal cord to the muscles and organs
Short dendrites and long axons
Neurones have three functions
Reception
Conduction
Transmission
Sensory neuron
Afferent neurone
Relays messages from receptors to the brain or spinal cord
Long dendrites and short axon
Cell body and dendrite are outside of the spinal cord; the cell body is located in a dorsal root ganglion
Interneuron ( relay)
Relays message from sensory neurone to motor neurone
Make up the brain and spinal cord
Short dendrites and short or long axon
Entirely within the spinal cord or CNS
Interconnect the sensory neurone with appropriate motor neuron
Structural features
Cell body (soma) Cell membrane Dendrite Axon hillock Axon. Myelin Nodes of ranvier Button
Synapse
Inside the neuron soma
Endoplasmic reticulum内质网 Cytoplasm细胞质 Ribosome核糖体 Golgi complex Mitochondria 线粒体 Microtubules Nucleus
Synaptic buttons
Synaptic vesicles
Neuro-transmitters
Resting membrane potential
Four keys: Na+ K+ CI- protein-
Five factors Random motion Different permeability of the membrane Electrostatic pressure Concentration gradients Sodium-potassium pump
Saltatory conduction
Passive conduction alone each myelin segment to next node of ranvier
New action potential generated at each node
Instant conduction alone myelin segments results in faster conduction than in unmyelinated axons
Glial cells : PNS
Schwann cells - similar to function of oligodendrocytes but in PNS, can guide atonal regeneration
Myelin and multiple sclerosis
Visual blurred and double vision Motor weakness of muscles Sensory numbness Coordination and balance Cognitive short and long term memory
Glial cells : CNS
Oligodendrocytes - extensions rich in myelin create myelin sheaths in CNS
Glial cells : CNS
Astrocytes ( star- cell)
Provide structural support
Clean up debris - phagocytosis
The synapse
Three parts Presynaptic terminal With vesicles containing neurotransmitters Receptors for reuptake Junction gap Where the NTs 'float' briefly after release Post-synaptic terminal With receptors for the NTs
3 types of directed synapses
Axoaxonic synapse
Increase the effects of one neuron on another ( presynaptic facilitation) others decrease the effects of one neuron in another ( presynaptic inhibition) The advantage is they selectively influence single synapses rather than the entire neuron