Wk06 Electron Beam Therapy Flashcards

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1
Q

For electron beam, the beam is made to strike on a ___________________.

A

Scattering foil

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2
Q

What is the use of a scattering foil?

A

To spread the beam to get a uniform electron fluence across the treatment field.

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3
Q

What is the scattering foil made of?

A

Low Z material eg. Aluminium
To prevent production of bremstrahlung x rays

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4
Q

What are the major characteristics of an electron central axis depth dose curve?

A
  1. A region of uniform dose —> can treat lesions with 1 single beam
  2. Rapid falloff of dose —> minimise dose to structures beyond the target
  3. High surface dose —> use to treat superficial lesions
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5
Q

Why is there a bremsstrahlung tail in electron depth dose curve?

A

It is caused by interaction between the electron beam and the machine components in its paths
Eg. Waveguide exit window, scattering foil, transmission ionization chamber

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6
Q

The bremsstrahlung tail is more prone to _______ energy electron beams.

A

High

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7
Q

How to estimate the treatment depth of election beam?

A

90% depth dose = E/3.2 cm
80% depth dose = E/2.8cm
Where E = most probable energy in MeV at the surface

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8
Q

For electron beams, energy ________________, surface dose ______________.

A

Increases ; increases

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9
Q

What are the two problems of electron dose distribution?

A
  1. Lateral constriction —> the corners might not receive enough dose
  2. Bulging out for low level isodose line

Both problems are more prone to high energy beams

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10
Q

How is penumbra measured in electron beam?

A

p80-20: distance from 80% to 20% isodose line at the specified depth R85/2.

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11
Q

The output and depth dose curve are both ___________ dependent.

A

Field size

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12
Q

The effect of the field size on the output and depth dose curve is significant when_______?

A

When the distance the field edge and central axis is smaller than the range of laterally scattered electron. i.e. more significant in smaller field size

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13
Q

Electron beam appears to originate from a point in space called __________. Which locate behind the __________.

A

Virtual source ; scattering foil

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14
Q

What is virtual source distance?

A

The distance from the virtual source to the surface

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15
Q

Electron beam is almost ______________ when produced.

A

Monoenergetic

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16
Q

What is Epk(0)?

A

The most probable energy of electron beam on the phantom surface

17
Q

What is \Ek(0)?

A

The mean energy of the electron beam on the phantom surface.

18
Q

What is R50?

A

Half-value depth on the percentage depth dose curve of the electron beam

19
Q

What is Rp?

A

Practical range of the electron beam

20
Q

What is Eko?

A

The mean energy of the electron beam at the exit window
- very narrow
- almost monoenergetic

21
Q

What ionization chamber is recommended for electron dosimetric measurement

A

Plane-parallel chambers

22
Q

Where is the reference point for plane-parallel chambers and cylindrical chambers respectively?

A

Plane-parallel chambers: inner surface of the entrance window, at the centre of the window

Cylindrical chambers: 0.5r deeper, where r is the radius of the air cavity

23
Q

What parameter is used to specified electron beam quality

A

R50 = the depth in water at which the absorbed dose is 50% of he maximum dose

24
Q

What is the ionisation chamber is actually measuring?

A

The quantity measured is the depth-ionization distribution. Conversion is needed

25
Q

What is reference depth Zref?

A

The position where the chamber should be placed. We need to place our chamber at different depths for different energy measurements.

26
Q

The choice of energy for electron treatment planning depends on:

A
  1. The depth of target volume
  2. Minimum target dose required
  3. Dose to a critical organ
27
Q

Dose beyond the inhomogeneity can be corrected by ___________________________ method

A

Coefficient of equivalent thickness (CET)

28
Q

What is the use of bolus

A
  1. Flatten out an irregular surface
  2. Reduce the penetration of electrons in part of the field
  3. Increase the surface dose
29
Q

What can be used for electron field shaping

A

Low melting point alloy eg. Cerrobend, which allow less than 5% of transmission

30
Q

How to calculate the lead thickness needed for shielding?

A

Energy in MEV / 2 + 1mm safety margin

If the lead is too thin, the dose may even be enhanced

31
Q

What lesions required internal shielding?

A

Lip, buccal mucosa, eyelid lesions

32
Q

What are the benefits of using internal shielding?

A
  1. Protect the structures beyond the target volumes
  2. Electron backscatter from lead will enhance the dose upstream up to 30-70%
    => hence, a suitable thickness of bolus or wax is placed between the lea and preceding tissue surface to reduce back scatter dose.