WK 2 Chapter 10

Question 1

movement of drug into the bloodstream

Answer 1

absorption

Question 2

higher to lower concentration

Answer 2

diffusion

Question 3

early liver metabolism

Answer 3

first-pass effect

Question 4

eliminating drugs from the body

Answer 4

excretion

Question 5

rate and amount of drug reaching systemic circulation

Answer 5

bioavailability

Question 6

time it takes for drug amount to be halved

Answer 6

half-life

Question 7

drug that binds to a receptor

Answer 7

agonist

Question 8

recipient site

Answer 8

receptor

Question 9

cooperative effect of two or more drugs

Answer 9

synergism

Question 10

one drug prolongs the effects of another drug

Answer 10

potentiation

Question 11

two drugs decrease each other’s effect

Answer 11

antagonism

Question 12

interference of drug with the effect of another

Answer 12

drug interaction

Question 13

opioids

Answer 13

drug abuse

Question 14

many drugs

Answer 14

polypharmacy

Question 15

over the counter

Answer 15

nonprescription drug

Question 16

combined effect of more than one agent

Answer 16

additive effect

Question 17

the antibiotic ciprofloxacin may have decreased absorption when taken with

Answer 17

magnesium- and aluminum- containing antacids

Question 18

Synergism refers to the effect of two or more drugs causing

Answer 18

a stronger effect

Question 19

which vitamin in certain green leafy vegatables interacts with warfarin

Answer 19

vitamin k

Question 20

garlic is an herb used for lowering cholesterol and modestly lowering blood pressure. which types of drugs would you caution patients about taking concurrently with garlic

Answer 20

antihypertensives

Question 21

patients who miss a dos of a scheduled medication should

Answer 21

consult with pharmacist or physician regarding the missed dose

Question 22

what patient variables may predispose a patient to drug interactions

Answer 22

age

Question 23

concurrent use of alcoholic beverages and sedatives may result in

Answer 23

excessive CNS depression

Question 24

the blood pressure medicine propranolol can reduce the effectiveness of an albuterol inhaler in an asthmatic patient. this is an example of

Answer 24

antagonism

Question 25

which of the following increases the drug metabolizing enzymes of the liver

Answer 25

smoking

Question 26

which of the following drugs may be given concurrently with grapefruit

Answer 26

acetaminophen

Question 27

chronic use of alcoholic beverages may interact with the drug phenytoin by

Answer 27

increasing liver enzyme activity

Question 28

vegetables such as broccoli and cabbage may inactivate

Answer 28

warfarin

Question 29

carbidopa is often prescribed in combination with levodopa in patients with parkinson’s disease. the addition of carbidopa decreases the amount of levodopa needed to have an effect, but it does not have a beneficial effect in these patients if given alone. this is an example of

Answer 29

potentiation

Question 30

any patient taking a monoamine oxidase (MAO) inhibitor (an antidepressant) should avoid all of the following food or beverages, except

Answer 30

diet coke

Question 31

factors that may result in a drug interaction include the following except

Answer 31

pharmacy intervention

Question 32

which nonprescription drug interacts with warfarin

Answer 32

aspirin (Bayer)

Question 33

Drugs that are most often abused include

Answer 33

opioids

Question 34

Antagonism refers to the effect of one drug causing another drug to have

Answer 34

a weaker effect

Question 35

which of the following drugs may cause peripheral neuritis in some patients

Answer 35

isoniazid

Question 36

all of the following drugs’ effects may be decreased by smoking, except

Answer 36

aspirin