Wk 2

Question 1

Genetics

Answer 1

Genetics is the study of genes in your body

Question 2

Genomics

Answer 2

Genomics is the study of genes as a whole in a population or group.

Question 3

What are the four types of genetic inheritance?

Answer 3

Autozomo dominant - trait expressed with one copy of a gene. 50% chance of passing on.

Autosomal recessive hyphen required two copies of the gene, one from each parent.

X linked ( dominant or recessive ) carried on the x chromosome.

multi-factorial- traits that cluster in families, but do not have characteristic pattern of inheritance.

Question 4

Autosomal

Answer 4

Any chromosome that is not a sex chromosome ( 22 pairs )

Question 5

Pedigree

Answer 5

The recorded ancestry

Question 6

Heterozygous

Answer 6

Having two different alleles of a particular gene.

Question 7

Carrier

Answer 7

Someone with a recessive allele, phenotype doesn’t show.

Question 8

Dominant

Answer 8

An overriding gene.

Question 9

Proband

Answer 9

A person serving as the starting point for a genetic study of a family.

Question 10

Recessive

Answer 10

A less dominant gene that only shows in a phenotype when received from both parents.

Question 11

Epigenetics

Answer 11

How hereditable changes in genes expression. A change in phenotype without a change in genotype.

Question 12

Sex linked

Answer 12

A gene or hereditable characteristic carried by a sex chromosome.

Question 13

Homozygous

Answer 13

Having two or more identical alleles of a particular gene.

Question 14

Genotype

Answer 14

Genotype is the collection of jeans responsible for the various genetic traits of an individual.

Question 15

Phenotype

Answer 15

Phenotype is a composition of genes that make up and organisms observable characteristics or traits. An example would be hair color eye color skin color.

Question 16

Penetrance versus expression

Answer 16

Penetrance - percentage of population that have a specific gene.

expression - how likely that gene is to be expressed in a particular population.

Question 17

What chromosomes increase your risk for breast cancer?

Answer 17

An autosomal dominant from chromosomes 13 parentheses BRCA2 ) and chromosome 17 ( BRCA1 ) This causes a 50% to 80% risk increase of breast cancer.

Question 18

What is Tay-Sachs? What population does it run in?

Answer 18

Tay-Sachs is a recessive gene where the absence of a vital enzyme called hexosomindase A (HEX-A). It causes death within the first 4 years of life. It runs common in Eastern European Jewish descendants.

Question 19

What je an is responsible for obesity? What BMI classifies obesity?

Answer 19

Leptin and its receptors are related to obesity. Hey BMI greater than 30 is considered obese.

Question 20

What are the three mechanisms of epigenetics?

Answer 20

DNA methylation
Histone modification
RNA-bas ed mechanisms

Question 21

What are the healthy people 2020 to topics on genomics?

Answer 21

Recommendation number one is for women with certain high risk family health history of breast and ovarian cancer to receive genetic counseling.

Recommendation number two is for all people who are newly diagnosed with colorectal cancer should receive counseling and educational material about genetic testing family members could benefit from knowing whether colorectal cancer in their family is the hereditary for m called Lynch syndrome.

Question 22

What aspects of the environment affect human health and quality of life?

Answer 22

Physical.
Chemical.
Biological.
Social.
Psychological.

Question 23

What is the hereditable form of colorectal cancer?

Answer 23

Familial adenomatous polyposis (adenomatous polyposis coli (APC)) also known as Lynch syndrome.

Question 24

What type of genetic inheritance is hemophilia?

Answer 24

Hemophiliais a sex-linked recessivedisorder. The abnormal gene responsible forhemophiliais carried on theX chromosome. Males have oneX chromosomeand one Ychromosome.

Question 25

Is sickle cell anemia dominant or recessive?

Answer 25

Recessive

Question 26

What is polygenic?

Answer 26

Many genes that could affect one trade

Question 27

What is epistasis?

Answer 27

One gene that could mask the effects of another.

Question 28

What is complementary

Answer 28

One gene that depends on another

Question 29

What is collaborative

Answer 29

Two jeans together that create a new phenotype