Wk 1 Flashcards
functions of the respiratory system
- gas exchange
- immunological
- biological
how does the immunological respiratory function protect the lungs from infection?
defense systems in both the airway and alveolus protect the lungs from infectionhy
hypoventilation definition
the state in which less air enters the alveoli, resulting in reduced O2 & increased CO2 levels in the blood
what can hypoventilation be due to?
breathing that is too shallow/ too slow, from a number of causes e.g. obesity, SC injury, NM diseases
is a shunt intrapulmonary or intracardiac?
both
what do both intrapulmonary / intracardiac forms of shunting reuslt in?
blood entering the left-sided circulation without an increase in O2 content
intra-cardiac shunting defintion
blood passing from right to left side of heart (e.g. via ventricular septal defect) without going through lungs to be oxygenated
what is a ‘dead space’
non gas-exchange areas
what areas are classified as ‘dead space’
conducting airways (trachea, bronchi, respiratory bronchioles)
V/Q mismatch when there is either:
- blood flow (Q) with reduced ventilation (V) –> low V/Q
- ventilation (V) with reduced blood flow (Q) –> high V/Q
shunt example
obstructed airway –> perfusion without ventilation
dead space example
obstructed blood vessel –> ventilation without perfusion (blood cant travel through but air can)
driving force for the exchange of gases between alveolar and capillary blood?
difference in partial pressure between the individual gases
2 main movements occurring in the respiratory system
- pump (NM-skeletal structures)
- lung (gas and secretion movement in the lungs)
Pump definition
to move air in and out of the lungwh
what does a ‘pump’ require?
neuro, musculo, and skeletal components to be intact e.g. SC, nerves, NMJ, muscles, bone, pleura
2 key functions within the lung:
- gas movement
- secretion movement
where does gas movement go
through the conducting airways to alveoli
where is the gas movement occurring?
between the alveolus and capillary
secretion movement occurs:
in the airways
Link between gas & secretion movement
if gas doesnt get into alveoli, clearance by gas flow will be ineffective
what happens if the airways are blocked / narrowed by secretions?
affects gas getting into alveoli (distribution of ventilation)
what can gas movement be divided into?
O2 and CO2 movement
what are the 2 components of secretion movement?
- MCC
- cough (back up clearance mechanism)
CO2 movement depends on…
the total volume of gas that moves in and out of the alveoli (Va) and is linked to the efficiency of the ‘pump’
what is O2 movement largely dependent on?
- alveolar surface area
- integrity of the interstitium
- pulmonary circulation
define respiratory load
what the muscles have to work against to:
1. move the chest wall (chest wall compliance)
2. move air through the airways (airway resistance)
3. expand the alveoli (lung compliance)
Is reduced O2 movement localised or generalised?
both
is reduced MCC mucus issues or cilia issues?
both