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Orgo Midterm Prepartion > Williamson Ether Synthesis > Flashcards

Williamson Ether Synthesis Flashcards

1
Q

Contained the tylenol tablet: how did you characterize that you got the final product?

A

State the IR SPECTRUM

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2
Q

Acetaminophen to phenacetin

A

Potassium carbonate
————->
Butanone

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3
Q

N-H bond peak

A

3300-3600

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4
Q

C=O bond peak

A

1600-1800

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5
Q

O-H bond peak

A

3200-3600

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6
Q

Williamson ether synthesis mechanism

A

SN2 reaction-2 steps

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7
Q

First step in SN2

A

Deprotonate the alcohol with a BASE⚾️ to form an alkoxide ion(alcohol would be acetaminophen)

Deprot. OH-> Alkoxide

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8
Q

Second Step in SN2

A

Produced alkoxide(nucleophile) -> reacts with the alkyl halide(electrophile) -> forms the ether phenacetin

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9
Q

Alkoxide

A

O^-

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10
Q

Melting point range of phenacetin

A

112-114 celsius

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11
Q

Percent Recovery

A

Pure/Crude*100%

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Orgo Midterm Prepartion (4 decks)

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