William's syndrome

Question 1

What is william’s syndrome?

Answer 1

This condition is characterized by mild to moderate intellectual disability or learning problems, unique personality characteristics, distinctive facial features, and heart and blood vessel (cardiovascular) problems.

Question 2

How are facial features altered?

Answer 2

Young children with Williams syndrome have distinctive facial features including a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips. Many affected people have dental problems such as teeth that are small, widely spaced, crooked, or missing. In older children and adults, the face appears longer and more gaunt.

Question 3

How does William’s syndrome affect intelligence?

Answer 3

People with Williams syndrome typically have difficulty with visual-spatial tasks such as drawing and assembling puzzles, but they tend to do well on tasks that involve spoken language, music, and learning by repetition (rote memorization).

Question 4

Cardiovascular symptoms of William’s syndrome?

Answer 4

Supravalvular aortic stenosis (SVAS)

Question 5

Musculoskeletal symptoms of william’s syndrome?

Answer 5

Abnormalities of connective tissue (tissue that supports the body’s joints and organs) such as joint problems and soft, loose skin.

Question 6

Other symptoms?

Answer 6

Affected people may also have increased calcium levels in the blood (hypercalcemia) in infancy, developmental delays, problems with coordination, and short stature.
Medical problems involving the eyes and vision, the digestive tract, and the urinary system are also possible.