White Lesions Flashcards

1
Q

Why does an oral lesion look white?

A
  1. Edema in the tissue
  2. Necrosis - variable thickness, +/- removable
  3. Superficial coatings - removable
  4. Keratin - more or change in type
  5. Thickening of the epithelium
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2
Q

Describe features of edema and the lesions it’s associated with

A

Disappears with stretching

-Leukoedema: buccal mucosae

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3
Q

Describe features of extrinsic coatings (organisms) and the lesions it’s associated with

A

+/- removable

-Coated and hairy tongue
-Plaque
-Candida: burning/irritated sensation- can also be red

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4
Q

Describe features of thermal or chemical injury and the lesions it’s associated with

A

Leads to cauterized or superficial sloughed epithelium: +/- removable

-Toothpaste, mouthwash

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5
Q

Describe features of increased Keratin and/or epithelial thickening and the lesions it’s associated with

A

Non-removable

-Frictional keratosis: linea alba, tongue/cheek chewing, alveolar ridge
-Smokeless tobacco keratosis
-Hairy Leukoplakia: immunosuppression
-Leukoplakia

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6
Q

Why do we care about white lesions?

A

-Some require no tx
-Others are easily treated
-Exclude precancerous change and systemic disease (HIV or inherited condition)

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7
Q

Linea Alba

A

-“white line”
-Non-removable, white line along the occlusal plane
-Caused by chronic, low-grade, frictional trauma
-Recognize - no tx

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8
Q

Leukoedema

A

-Asymptomatic
-Non-removable, opalescent/pale white appearance of the buccal mucosa that diminishes when stretched
-More common in black adults and smokers
-Recognize - no tx

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9
Q

What are the key questions for Leukoedema?

A

-Is it removable?
-Does it disappear when stretched?
-Is it on the other side?
-Is it asymptomatic?

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10
Q

Coated Tongue

A

-Very common white coating on the dorsal tongue
-May have malodor
-Can be misdiagnosed as candidiasis
-Tx: scrape tongue

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11
Q

Hairy Tongue

A

-Elongated, discolored, filiform papillae
-Associated with smoking
-Discoloration (brown, black, green, yellow) due to bacteria, food stains, tobacco
-Asymptomatic or gagging if long. Bad taste
-Tx: brush tongue and stop smoking to reduce lesions

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12
Q

Dentifrice-Associated Slough

A

-Common, often related to tartar-control, whitening, sensitivity-control, multi-care toothpaste or overuse of mouthwash
-Mild peeling, sloughing of superficial keratin layers, labial/buccal mucosa and floor of mouth, usually asymptomatic
-Bland toothpaste formula may be helpful

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13
Q

Morsicatio (cheek/tongue chewing)

A

-White, ragged, non-removable but possibly partially peeling surface texture
-Labial and anterior buccal mucosa and lateral tongue
-Caused by chronic, low-grade, frictional trauma
-Management:
1. Recognize - typically no tx, unless extensive which might require biopsy to exclude premalignant changes
2. Pt. education and possible occlusal guard

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14
Q

Alveolar Ridge Keratosis

A

-Look for asymmetry, spread off the ridge, erythema or ulceration to warrant biopsy
-Study with 477 cases: 97.9% lacked dysplasia. The 2.1% dysplastic cases contained 1+ of the following: verrucous appearance, tobacco or alcohol use, multiple white lesions and previous SCC

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15
Q

Nicotine Stomatitis

A

-White keratotic change induced by heat of tobacco smoking or hot beverages
-Posterior hard palate, soft palate
-Elevated papules with ed center (orifices of minor salivary gland cducts) and white borders
-Not precancerous; resolution in 1-2 weeks following habit cessation

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16
Q

Hairy Leukoplakia

A

-Epstein-Barr Virus (EBV) induced lesion often with superimposed candidiasis
-Usually HIV-infected or other immune compromise. Rare in healthy patients
-Non-removable white plaque(s) of the lateral tongue
-Faint vertical strands to thick furrowing with shaggy keratotic surface
-Tx: usually resolved with control of HIV infection

17
Q

Hairy Leukoplakia Histology

A

-Thick, irregular parakeratin
-Candida infection common
-Hyperplastic (thicker) epithelium with “balloon cells” that show EBV by in situ hybridization
-No dysplasia
-Minimal inflammation