What is the typical study design for a prognostic test

Question 1

What are the 2 typical study designs for a prognostic test?

Answer 1

Cohort study and case controlled study

Question 2

Takes a group of individuals exposed to a disease and follows them prospectively over time (usually) to record how their disease progresses to an outcome when compared to a similar group who do not have the disease.

Answer 2

Cohort study

Question 3

Begins by identifying a group of individuals with the disease and retrospectively compare them to a group of individuals without the disease to highlight any significant differences in exposure which may act as prognostic factors.

Answer 3

Case controlled study

Question 4

Reasons for a case controlled study design

Answer 4

Rapid investigation in to potential risk factors for outcome

Question 5

What are the problems with a prospective study design?

Answer 5

They are difficult to conduct correctly and ethical concerns