What is the route of transmission and clinical/pathogenic features of this food-borne pathogen?

Question 1

Bacillus anthracis

Answer 1

Route:Insufficiently cooked contaminated meat

S/S: NVD (bloody), fever, malaise

Tx: penicillin

Question 2

Bacillus cereus

Answer 2

Route: meats, unrefrigerated rice

Pathogenesis: Preformed toxin

S/S: NVD (preformed toxin), or watery diarrhea and cramps

Tx: supportive care

Question 3

Brucella

Answer 3

Route: raw milk, cheese

S/S: fever, myalgia, arthralgia, bloody diarrhea

Tx: Rifampin and Doxyclycine

Question 4

Campylobacter jejuni

Answer 4

Route: undercooked poultry, unpasteurized milk, water

Pathogenesis: invasion

S/S: fever, bloody diarrhea

Tx: Supportive care

Question 5

Clostridium botulinum

Answer 5

Route: honey, home canning, corn syrup

S/S: NVD, descending muscle weakness

Tx: supportive care OR botulinum antitoxin OR botulism IgG (infants)`

Question 6

Clostridium perfringens

Answer 6

Route: meats, poultry

Pathogenesis: preformed toxin

S/S: watery diarrhea. no fever

Tx: Supportive care

Question 7

EHEC

Answer 7

Route: undercooked beef, fruits and vegetables, unpasteurized milk

Pathogenesis: cytotoxin

S/S: severe bloody diarrhea

Tx: Supportive care

Question 8

ETEC

Answer 8

Route: water or food contaminated with human feces

Pathogenesis: enterotoxin

S/S: watery diarrhea

Tx: Supportive care

Question 9

Listeria monocytogenes

Answer 9

Route: ready-to-eat deli meat, unpasteurized milk, fresh soft cheeses

Pathogenesis: invasive and neurotropic

S/S: enteric fever

Tx: supportive care and antibiotics

Question 10

Salmonella spp.

Answer 10

Route: Eggs, poultry, unpasteurized milk

Pathogenesis: invasion

S/S: diarrhea–> enteric (typhoid) fever

Tx: Supportive care. Antibiotics for S. Typhi and S. Paratyphi

Question 11

S. aureus

Answer 11

Route: unrefrigerated meats, potato salad, cream pastries

Pathogenesis: preformed toxin

S/S: NVD

Tx: supportive care

Question 12

Vibrio cholerae

Answer 12

Route: contaminated water, fish, shellfish, street food

Pathogenesis: enterotoxin

S/S: profuse rice water diarrhea

Tx: aggressive IV rehydration, tetracycline or doxycycline

Question 13

Yersinia enterolytica

Answer 13

Route: undercooked pork, unpasteurized milk, tofu

Pathogenesis: invasion

S/S: Appendicitis-like symptoms (NVD, fever, pain)

Tx: supportive care, or antibiotics for septecemia

Question 14

Shigella

Answer 14

Route: Food/water contaminated by human feces (e.g. food workers)

Pathogenesis: invasion

S/S: fever, bloody diarrhea

Tx: supportive care

Question 15

Plesiomonas shigelloides (no answers- just want to remember as an enteric pathogen)

Answer 15

!

Question 16

Helicobacter (no answers, just want to remember as an enteric pathogen)

Answer 16

!