What is the cause? Flashcards
Iron Deficiency
Menstrual loss, bleeding, dietary intake, absorbtion issues, cancer, pregnancy
Anemia of Chronic Disease
Underlying disease: chronic inflamation, alcoholism, malignancy
Lead intoxication
Exposure to lead including eating paint chips
Hereditary Spherocytocis
Mutated proteins cause weakened membrane (spectrin, ank, band 3) and spherocyte formation
Thalassemia
Different hemoglobin chains present than normal- Autosomal recessive disorders
B12 Deficiency
Vegan diet, pernicious anemia (autoimmune destruction of IF cells), failure to produce IF, malabsorbtion, defective transport or storage, metabolic pathway deficits
Folate deficiency
Alcoholism, overcooking food, malabsorbtion, inadequate intake, parasitic infection, pregnancy
G6PD Deficiency
X-linked recessive enzyme deficiency, triggered by lots of foods (fava beans) and chemicals
Autoimmune Hemolytic Anemia
Infection, malignancy, autoimmune, drug induced
PK deficiency
Second most common enzyme deficiency
Sickle Cell
Genetic mutation causing a Glu->Val transformation on hemoglobin leading to sickled RBC’s and hemolysis
Anemia due to renal dysfunction
Renal dysfunction.
Endocrine related anemia
Hyper, hypo thyroidism, adrenal insufficiency
Sideroblastic (Deposits of iron in mitochondria of erythroid precursors)
Chronic alcoholism, B6 deficiency, Lead poisining, X linked recessive
Malnutrition through lack of protein and calories
Self explanatory