Wetting Of Powders Flashcards

0
Q

What does wetting depend on?

A

Surface properties of powder and vehicle

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1
Q

What does wetting precede?

A

Dissolution or dispersion of a powder,granule or tablet

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2
Q

What is the boundary of two phases called?

A

Interface

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3
Q

What is interfaces of gas/liquids?

A

Water and air , bubbles

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4
Q

What is the interface of gas/solids?

A

Table top

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5
Q

What is the interface of liquid/liquid?

A

Immiscible solvents, emulsion

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6
Q

What is the interface of liquid/solid?

A

Water drop on table, suspension

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7
Q

What is the interface of solid/solid?

A

Powder particles in contact

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8
Q

What are gas/liquid and gas/solid interfaces also called?

A

Surface

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9
Q

By which bonds are molecules in the bulk of each phase attracted to each other by equally in all directions?

A

Hydrogen bonding in water, London forced in oil

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10
Q

What are forces like at the boundary?

A

Unequal

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11
Q

What is the spontaneous movement of liquids?

A

Form the interface into the bulk

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12
Q

What does imbalance lead to?

A

Tension

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13
Q

What is interfacial tension?

A

The energy per unit area (force per unit distance) at the surface between phases

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14
Q

What is interfacial tension commonly expressed in?

A

milli-Newtons/meter

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15
Q

What is surface tension?

A

Energy required to create a unit area of surface: surface free energy / unit area = surface tension

16
Q

What liquids have higher surface tension?

A

Liquids with higher intermolecular attraction have higher surface tension: polar liquids

17
Q

What are high energy solids?

A

Metals and salts

18
Q

What is the problems with solid surfaces?

A

More complex:
Lack of mobility of molecules
Direct measurement of surface energy impossible
Exposure of different crystal faces

19
Q

What is sprinkled on water float on solid/liquid interface?

A

Talcum powder

20
Q

What must occur before immersion (wetting)?

A

Liquid must displace air and spread over the surface of the solid

21
Q

What is wettability?

A

The tendency of one liquid to spread on or adhere to a solid surface

22
Q

What does wettability refer to?

A

Interaction between liquid and solid phases

23
Q

What is the contact angle?

A

Ten angle made by the liquid with a solid surface

24
Q

What is the degree of the angle when wetting is complete?

A

0

25
Q

What can the degree of the angle increase to in non-wetting situation?

A

189 spherical droplet

26
Q

What do factors reducing slid-liquid and liquid air interfaces favour?

A

Wettability- non-polar liquids have better wettability

27
Q

What does the greater the value of solid-air mean?

A

The greater the chance for wetting (high energy solids)

28
Q

What is the contact angle of a nonwettable solid on a liquid surface?

A

> 90

29
Q

How can wettability be improved?

A

Reducing the surface tension of liquids (surfactants)

Use low surface tension liquids (addition of co-solvents)

30
Q

What can surfactants do?

A

Lowers the liquid-air interfaces

Absorbs to powder surface and reduce solid-liquid interfaces