weird conditions

Question 1

adult onset stills disease
- major criteria
- minor criteria

Answer 1

• major : fever >1 w
• arthralgia/arthritis
• typical rash
• leukocytosis >10K
• > 80% granulocytes

minor
- sore throat
- lymphadenopathy
- hepatosplenomeg, splenomeg
- abN liver function studies
- negative ANA&RF

Question 2

mild-moderate disease still disease tx ?

Answer 2

nsaid

Question 3

mod-severe disease or failed nsaids

Answer 3

glucocorticoid/anaknra

Question 4

inclusion body myositis hallmark

Answer 4

finger flexor weakness

Question 5

can you have high CK in inclusion body myositis??

Answer 5

yes, but they are asymptomatic

Question 6

isolated dysphagia with incluson body myositis?

Answer 6

yes

Question 7

role for immunosup meds in in clusion body myositis?

Answer 7

nil

Question 8

what’s vexas presentation
- asscoiated with

Answer 8

fever
systemic inflammation
organ inflamamtion

macrocytosis and myleosuoppression

Question 9

vexas associated with heme conditions
increased risk of what ?

Answer 9

mds, mm, mgus

++ risk vte