Weight loss Flashcards
Mechanisms of weight loss
Reduced intake
Reduced digestion, absorption
Increased lossess
Increased requirements
Reduced intake
Inappropriate feeding, unable to obtain, dental disease, dysphagia (strangles), pain, gatric disease (must be severe)
Reduced digestion, absorption, assimilation of nutrients
Dental, malabsorption syndromes (cyathostominosis- hypoalbuminaemia, diarrhoea, inflammatory)
Liver disease
Intestinal disease - may also cause chronic diarrhoea
Infiltrative bowel diesease - inflammatory or neoplastic infiltrates
Increased losses
Protein losing enteropathy - cyathostominosis, large strongyles
Rarely protein losing nephropathy, but severe if so
Sequestration to body cavity - pleuritis, peritonitis
Increased requirements
Preganancy, lactate, sepsis, neoplasia
History for weight loss
Diet (specifics), parasite control, age, activity, length of weight loss, dental, diarrhoea, inappetance, colic, type of pasture - other horses?
Physical exam
Muscle waste - head, cervical, epaxial
Oedema - ventral, limbs
Faecal staining on hindquarters
HR, abnormal lung sounds, GI motility
Dental
Faeces, parasites, sand grass
Neutrophilia
more common with parasite infection
Eosinophilia
Parasite, general inflammation
Anaemia
Chronic disease
Inflammatory markers
SAA - acute
Fibrinogen - 4-8h after initial inflammation
Total protein decrease
Hypoalbuminaemia
Hypoglobulinaemia
Masked by concurrent hypovolaemia
Albumin - GI more common than renal, effusions (peritoneal, pleural), liver - rare
Globulin - GI loss
Total protein increase - Hyperproteinaemia
Hyperalbuminaemia - chronic inflammatory - inc. cyathostominosis
Hyperglobulinaemia - infection, inflammation, neoplasia
Oral glucose test
Withhold food overnight
1g/kg 10-20% solution by nasogastric solution
Keep calm - insulin increase with stress
Blood glucose should double in 90 minutes and decrease with insulin response
Limitations - does not only assess SI function - small amount absorbed in LI
Delayed flat curve - delayed gastric emptying, poorly starved
Intestinal ultrasound
SI thickness
LI thickness
SI >4mm abnormal
LI >6mm abnormal