Week One Flashcards

1
Q

Name the two major types of cells of the nervous system

A

Neurons & glia

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2
Q

Neurons can manipulate _____ _____ more quickly than other cells can

A

Electrical activity

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3
Q

True or false: the main function of a neuron is communication via electrochemical signals

A

True

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4
Q

The _____ is where specialized communication between neurons takes place via _____

A

Synapse & neurotransmitters

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5
Q

True or false: neurons are not polarized

A

False

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6
Q

The flow of information within a neuron is GENERALLY _____ —> _____ —> _____

A

Dendrite —> axon —> synapse

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7
Q

Microtubules run from - —> +, where the cell body is negative/positive (choose one) and the synapse is negative/positive (choose one)

A

Negative, positive

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8
Q

Kinesin is a +/- (pick one) while dyenin is a +/- (pick one) directed motor. Myosin motors are _____ dependent

A

+, -, actin

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9
Q

True or false: molecular motors only travel along axons

A

False

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10
Q

Name the three main types of glia in the CNS

A
  1. Microglia
  2. Oligodendrocytes
  3. Astroglia
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11
Q

In addition to forming the myelin sheath, oligodendrocytes help to _____ the axon

A

Nourish

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12
Q

Astrocytes are the most abundant type of glia. Name the six main functions they provide

A
  1. Scaffolding between neurons
  2. Creates the barrier within the BBB
  3. Help filter waste
  4. Modulate synapse via uptake of neurotransmitters
  5. Give neurons nutrients
  6. Provide pH of the environment
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13
Q

Microglia are the _____ cells of the nervous system

A

Immune

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14
Q

Microglia have direct/indirect effects on brain activity via their _____ signals

A

Direct, immune

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15
Q

Name the 5 primary ways we stain fixed tissue samples

A
  1. Golgi staining
  2. Intracellular fluorescent dye injection
  3. Intracellular enzymatic labeling
  4. Nissl staining
  5. Cresyl violent stains
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16
Q

Golgi staining labels _____ _____

A

Individual neurons

17
Q

Nissl staining labels the _____ of cells

A

Nucleus

18
Q

Cresyl staining labels the _____ in the _____ of all cells

A

RNA & ER

19
Q

Does immunohistochemistry label cells in a culture or a fixed slice of tissue?

A

Fixed slice of tissue

20
Q

Does immunocytochemistry label cells in a culture or a fixed slice of tissue?

A

Cells in a culture

21
Q

Indirect immunolabeling uses one/two (choose one) antibodies while direct immunolabeling uses one/two (choose one) antibodies

A

Two, one

22
Q

Genetic expression of _____ _____ allows for scientists to observe specific cells in living organisms

A

Fluorescent proteins

23
Q

True or false: Retrograde circuit tracing can be done in fixed tissue or a live organism

A

False (can only be done in live organism)

24
Q

A patch clamp records the activity of many/one (choose one) neurons

A

One