Week 8 - Guest Lecture Flashcards

1
Q

advantages: BIOCERAMICS

A
  • wear resistance
  • corrosion resistance
  • easy/ cheap manufacture
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2
Q

disadvantages: BIOCERAMICS

A
  • brittle

- difficult/ costly manufacture

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3
Q

applications: BIOCERAMICS

A
  • bone and dental replacements
  • drug delivery
  • cancer treatment
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4
Q

generations: BIOCERAMICS

A
  1. bioinert
    - accepted, no interation
  2. bioactive OR resorbable
    - interaction
  3. bioactive AND resorbable
    - supporting full self-healing
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5
Q

examples: BIOCERAMICS

A

Al2O3

  • most widely used for technical ceramic applications
  • cups/ heads in hip/knee implant
  • -> high fracture toughness/ wear R/ corrosion R
  • controlled drug delivery
  • -> high SA, easy functionalisation

CaP-based

  • similar to bonetooth mineral HA
  • -> form stable interface, simulates and guide cell growth
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6
Q

Define: Piezoelectricity

A

Transformation of mechanical stress to electric potential

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7
Q

Define: Direct piezoeffect

A

mechanical stress to electric potential

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8
Q

Define: Indirect piezoeffect

A

electrical field into mechanical strain

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9
Q

Piezoelectric graph

A
  • LOOK AT GRAPH
  • cofficient/ tensor (slope) = d
  • components determines by crystal symmetry
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10
Q

ex-vivo applications PIEZO

A
  • motion/ vibration sensors
  • energy harvesting
  • buzzers
  • ultrasound devices
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11
Q

in vivo applications PIEZO

A
  • sensing and monitoring
  • energy harvesting
  • temporary muscle function
  • vibration damping
  • cell stimulation and guidance
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12
Q

cell stimulation and guidance applications

A

in vivo culturing
- medical treatment of degenerative diseases
in vivo cell stimulation
- auditory nerves - cochlear implants
- guided cell growth - scaffolds, implants

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13
Q

Piezoelectric materials factors

A
  1. sufficient stimulus
  2. chemical stability
  3. mechanical compatibility
  4. microstructural compatibility
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14
Q
  1. Sufficient stimulus
A

WHAT

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15
Q
  1. Chemical stability
A
  • no controlled solubility
  • swelling/ loss of mechanical integrity
  • changes to surface chemistry
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16
Q
  1. Mechanical compatibility
A
  • stable under compression/ tension/ shear
  • similar elastic properties to tissue
  • wear and fracture during usage
  • stress shielding
17
Q
  1. Microstructural compatibility
A
  • allows cell ingrowth/ attachment