Week 8 CO2 absorption Flashcards
Why is granule hardness important? How is it tested? What should the hardness number be?
- excessive powder → channeling, resistance, caking
- tested with steel ball bearings & screen pan
- % of original remaining = hardness number
- hardness number should be >75
Describe the gas flow through the CO2 absorber during the inhalation phase of respiration.
What is the absorptive capacity of baralyme?
26 liters of CO2 per 100 grams absorbent granules
In CO2 absorbers, color conversion signals….
absorber exhaustion
Describe how Compound A can be a problem with CO2 absorbents. What do you manufacturers recommend related to this issue? How do practitioners avoid this problem?
- CO2 granules degrade volatile anesthetic agents to some extent, especially sevoflurane
- when degraded by a strong base in CO2 absorbents (containing KOH and to a lesser extent, NaOH), sevoflurane forms Compound A at concentrations which have been demonstrated to be nephrotoxic in rats
- does not appear to be an issue with absorbents with no KOH/NaOH
- Manufacturer recommens no more than 2 MAC hours at flow rates of 1 to <2 L/min
- MAC hours = MAC x hours of inhalation agent given
- 1 MAC x 2 hours = 2 MAC hours
- 1/2 MAC x 4 hours = 2 MAC hours
- MAC hours = MAC x hours of inhalation agent given
- Most practitioners use at least 2 liters of FGF with sevo
- although this practice is not evidenced based necessarily no connection between renal damage and sevoflurane use has been determined after extensie clinical use
- ALSO, new absorbents do not appear to form Compound A
- although this practice is not evidenced based necessarily no connection between renal damage and sevoflurane use has been determined after extensie clinical use
Describe the calcium hydroxide reaction.
Describe the soda lime reaction.
- carbon dioxide combines with water to form carbonic acid
- carbonic acid reacts with hydroxides to form sodium (or potassium) carbonate and water and heat
Which volatile anesthetic is associated with the highest accumulation of carbon monoxide?
desflurane
How many liters of CO2 are 100g soda lime capable of absorbing?
26 liters of CO2/100 g of absorbent granules
What is channeling? Why is it a problem? How do some manufacturers try to prevent?
-
preferential passage of exhaled gas flow through absorber via pathways of low resistance
- results from loosely packed granules
- air space occupies 48-55% of the volume of the canister
- absorbent along channels may exhaust
- CO2 may filter though channels not visible
- CO2 monitoring may be affected
- some manufacturers now use a polymer to bind the granules in pre - formed channels to prevent channeling
What is the composition of Baralyme?
- 80% calcium hydroxide
- 20% barium hydroxide
- small amounts of sodium hydroxide and potassium hydroxide may be added
- (no hardening agent)
- (no water)
- granules are 4-8 mesh
What is the makeup of calcium hydroxide lime (aka amsorb plus)?
- 80% calcium hydroxide
- 16% water
- 1-4% calcium chloride
- calcium sulfate and polyvinylpyrrolidine
- added hardness
T or F: Color of the absorbent can revert back with rest.
True;
**especially in NaOH containing formulations**
1 pound of lithium hydroxide absorbs how many pounds of carbon dioxide?
.91 pounds of carbon dioxide
Desribe the litholyme reaction.
end product: lithium carbonate, water, heat