Week 8 CO2 absorption Flashcards

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1
Q

Why is granule hardness important? How is it tested? What should the hardness number be?

A
  • excessive powder → channeling, resistance, caking
  • tested with steel ball bearings & screen pan
    • % of original remaining = hardness number
  • hardness number should be >75
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2
Q

Describe the gas flow through the CO2 absorber during the inhalation phase of respiration.

A
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3
Q

What is the absorptive capacity of baralyme?

A

26 liters of CO2 per 100 grams absorbent granules

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4
Q

In CO2 absorbers, color conversion signals….

A

absorber exhaustion

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5
Q

Describe how Compound A can be a problem with CO2 absorbents. What do you manufacturers recommend related to this issue? How do practitioners avoid this problem?

A
  • CO2 granules degrade volatile anesthetic agents to some extent, especially sevoflurane
  • when degraded by a strong base in CO2 absorbents (containing KOH and to a lesser extent, NaOH), sevoflurane forms Compound A at concentrations which have been demonstrated to be nephrotoxic in rats
    • does not appear to be an issue with absorbents with no KOH/NaOH
  • Manufacturer recommens no more than 2 MAC hours at flow rates of 1 to <2 L/min
    • MAC hours = MAC x hours of inhalation agent given
      • 1 MAC x 2 hours = 2 MAC hours
      • 1/2 MAC x 4 hours = 2 MAC hours
  • Most practitioners use at least 2 liters of FGF with sevo
    • although this practice is not evidenced based necessarily no connection between renal damage and sevoflurane use has been determined after extensie clinical use
      • ​ALSO, new absorbents do not appear to form Compound A
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6
Q

Describe the calcium hydroxide reaction.

A
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7
Q

Describe the soda lime reaction.

A
  • carbon dioxide combines with water to form carbonic acid
  • carbonic acid reacts with hydroxides to form sodium (or potassium) carbonate and water and heat
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8
Q

Which volatile anesthetic is associated with the highest accumulation of carbon monoxide?

A

desflurane

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9
Q

How many liters of CO2 are 100g soda lime capable of absorbing?

A

26 liters of CO2/100 g of absorbent granules

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10
Q

What is channeling? Why is it a problem? How do some manufacturers try to prevent?

A
  • preferential passage of exhaled gas flow through absorber via pathways of low resistance
    • results from loosely packed granules
  • air space occupies 48-55% of the volume of the canister
  • absorbent along channels may exhaust
    • CO2 may filter though channels not visible
    • CO2 monitoring may be affected
  • some manufacturers now use a polymer to bind the granules in pre - formed channels to prevent channeling
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11
Q

What is the composition of Baralyme?

A
  • 80% calcium hydroxide
  • 20% barium hydroxide
  • small amounts of sodium hydroxide and potassium hydroxide may be added
  • (no hardening agent)
  • (no water)
  • granules are 4-8 mesh
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12
Q

What is the makeup of calcium hydroxide lime (aka amsorb plus)?

A
  • 80% calcium hydroxide
  • 16% water
  • 1-4% calcium chloride
  • calcium sulfate and polyvinylpyrrolidine
    • added hardness
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13
Q

T or F: Color of the absorbent can revert back with rest.

A

True;

**especially in NaOH containing formulations**

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14
Q

1 pound of lithium hydroxide absorbs how many pounds of carbon dioxide?

A

.91 pounds of carbon dioxide

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15
Q

Desribe the litholyme reaction.

A

end product: lithium carbonate, water, heat

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16
Q

State the color of the indicator when absorbent is fresh vs when absorbent is exhausted for phenolphthalein, ethyl violet, clayton yello, ethyl orange, and mimosa 2.

A
17
Q

Why was baralyme voluntarily pulled from the market?

A
  • implicated in fires
    • no water in makeup of baralyme
18
Q

Describe the size and shape selection of absorbent granules.

A
  • 4-8 mesh → granule size = number of openings per inch in a sieve through which particles can make it through
  • irregular shape = increased surface area
  • small granules increase resistance
  • blend of small and large minimize resistance with little sacrifice in absorbent capacity
19
Q

What is the makeup of litholyme (lithium hydroxide monohydrate)?

A
  • 75% lithium hydroxide
  • 12-19% H2O
  • <3% lithium chloride

**note: there is also an anhydrous formulation**

20
Q

What is the most common CO2 absorber and what is its critical pH?

A

ethyl violet

critical pH = 10.3

21
Q

Replace CO2 absorbent when ___ - ___ % color change.

A

50-70%

22
Q

Calcium hydroxide lime is capable of absorbing how many liters of CO2 per 100 g absorbent granules?

A

10 liters of CO2 / 100g of absorbent granules

23
Q

What is the make up of soda lime?

A
  • 4% sodium hydroxide
  • 1% potassium hydroxide
  • 15% H2O
  • 0.2% silica
  • 80% calcium hydroxide
24
Q

List the Anesthesia Safety Foundation Recommendation on Safe Use of Carbon Dioxide Absorbents.

A
  • turn off all gas flow when the machine is not in use
  • change absorbent regularly
  • change absorbent whenever the color change indicates exhaustion
  • change all abosrbent, not just one canister
  • change absorbent when uncertain of the state of hydration, such as if FGF is left on for extended time
  • low flows preserve humidity in granules
25
Q

1 pound of calcium hydroxide can absorb how many pounds of carbon dioxide?

A

.59 pounds of carbon dioxide

26
Q

Describe the flow of gas during the exhalation phase of respiration.

A
  • gases flow through the mask → into the rebreathing bag → and out the apl valve
  • fresh gas continues to flow from the common gas outlet at the machine into the common gas inlet at the absorber
27
Q

A problem with CO2 absorbents is the accumulation of carbon monoxide. How and why does this happen? What can happen to patients?

A
  • CO known to accumulate in desiccated (dry) NaOH and KOH containing absorbents when they are not used for 24-48 hours
    • high flow through a system for prolonged time (such as if one forgets to run down the O2 flow over the weekend) = dries it out
    • with dried out absorbent, a slow reaction occurs with the volatile anethetic agents and absorbents that produces CO
    • **can result in critically high levels of carboxyhemoglobin in exposed patients**