Week 8 Flashcards
When thinking about risk factors for breast and ovarian cancer, how far back should family history be assessed?
3 generations back (mother, grandmother, or great grandmother)
What average of cancer is related to genetics?
On average about 10%, but ovarian and breast cancer is more like 70-80%
What are the professions that a person with a mass will present to?
Any one of these can be visited
PCP: 1st line of contact
Oncologist: if pre-existing relationship is present
Geritologist: If pt is older
What are the professions included in a cancer care team?
- Physicians providing oncology care
- Clinicians providing psychosocial support and spiritual workers
- Palliative care clinicians (Including hospice at end of life
- Rehab clinicians
- Physician assistant
- Pharmacist
- Nurses
What percentage of masses are found by palpation?
10%
___ is the preferred method and the way in which we get a definitive diagnosis of cancer
Biopsy is the preferred method and the way in which we get a definitive diagnosis of cancer
What types of cancer is a bone marrow biopsy used for?
Leukemia, myeloma, lymphoma
liquid tumors
What are the characteristics of a bone marrow biopsy?
- Sample of bone marrow
- Back of your hipbone
- Uses a long needle
What are the characteristics of an endoscopic biopsy?
- Tube is inserted into a cavity for imaging and tissue removal
- Allows for aspiration
What types of cancer is an endoscopic biopsy used for?
Lung, bladder, colorectal,
gastrointestinal
What is a needle biopsy used for?
To extract cells or tissue
What types of cancer is a needle biopsy used for?
Breast, liver, lung, prostate
What are the various types of needles that can be used in a needle biopsy?
- Fine needle (most commonly used)
- Core needle
- Vacuum assisted
- Image guided
- Stereotaxy (most common. Uses imaging during to allow the proper position of the biopsy. Used for the brain, and breast)
What type of imaging is a mammogram?
Xray imaging
What is the criteria for being a candidate for hormone therapy?
The receptor status has to be positive in order to be a candidate
What does it mean when a cancer pt’s margins are positive?
There are cancer cells on the edges of the specimen that was extracted. This results in either a second biopsy, a larger procedure or extra chemotherapy
What percent of cancer survivors with a body structure/function issue gets referred to PT?
About 20%
What does the CoC (commission on cancer) do?
It says that every cancer survivor has to have a survivorship care plan, which will document some details about the pt’s cancer, the treatment, the prevalence and severity of the side effects, and how they are being managed
What does a CARF (Commission on Accreditation of Rehabilitation Facilities) do?
It gives some structure around the prospective surveillance of pts with cancer
• Response to the medical management of cancer
• Side effects they have and how they are being addressed
What are some examples of a CoC (commission on cancer) accredited facility?
- Hospitals
- Breast cancer centers
- Cancer centers
As a PT working in a CoC accredited facility, what should be the 1st question asked?
Who is managing the pt’s survivorship care plan and how do I see/participate in it?
Under the CoC, what is the standard that mostly relates to the PT, and why?
E11, because it says cancer survivors have to be screened for stress at least once in the cancer care continuum. This screening includes an assessment of any physical issues the pt may be having
What are some of the body structure impairments found in pts with breast cancer?
- ↓Range of motion
- Muscle weakness
- CIPN (chemotherapy induced peripheral neuropathy)
- Lymphedema risk
What are some of the individual limitations found in pts with breast cancer?
- Difficulty reaching
- Difficulty lifting
- Dizziness
What are some of the society limitations found in pts with breast cancer?
• Unable to meet specific job
demands (60% returns to work, but many report to being able to work at the same level)
• Unable to fulfill life roles
What are some of the environment limitations found in pts with breast cancer?
- Unemployment
- Travel Precautions
- Housework Demands
What are the personal factors that impacts a pt with cancer?
- Loss of Identity
- Body Image Changes
- Anxiety
When selecting outcome measurement tools for the evaluation of pts with cancer, what is the recommendation on which ones to pick?
Try to pick those that are condition/region specific d/t having the sensitivity to pick up on immediate or monthly changes that the pt may see
When do we use generic health status outcome measure for pts with cancer?
For 6 months or annual assessments
When picking an outcome measure for a pt with cancer, we need to think about its use within the prospective surveillance model. What does this entail?
Is it going to be a tool that is well suited for repeated measures? (this is what we want). The prospective surveillance model is the one being recommended.
What are the characteristics of the prospective surveillance model?
• Baseline assessments
• Regular screenings
- Every 3-6 months for the first 3 years
- Every 6-12 months for the next 2 years
- Annually thereafter
• Early identification and treatment of side effects
• Multidisciplinary team approach
• Model has been recommended
What are the pros of the prospective surveillance model?
- Increased patient education and satisfaction
- Early identification
- Early treatment
- Reduced risk of disability
- Builds patient’s trust
- Builds patient’s self management skills
What are the cons of the prospective surveillance model?
- Extra Encounters
- Financial Costs
- Human Capital
- Referral Points
- Documentation
- Hypervigilance
What are the recommendations to keep in mind when thinking about the screening and examination of a pt with cancer?
• Consider using prospective surveillance for the early
identification of side effects (screening)
• Use the ICF model as your framework for evaluation and
selection of tools (examination)
• Choose Functional Reporting Tools
- Global/generic/condition measure (full systems screen)
- Impairment-specific or condition/region measures (preferred)
• Document test and measure changes over time to demonstrate progress towards goals
What are the side effects of chemotherapy drug methotrexate?
• “fever, chills, swollen lymph glands, night sweats, weight loss;
• vomiting, white patches or sores inside your mouth or on your lips;
• diarrhea, blood in your urine or stools;
• dry cough, cough with mucus, stabbing chest pain, wheezing, feeling short of breath;
• seizure (convulsions);
• kidney problems - little or no urination, swelling in your feet or ankles;
• liver problems - stomach pain (upper right side), dark urine, jaundice
(yellowing of the skin or eyes);
• nerve problems - confusion, weakness, drowsiness, coordination problems,
feeling irritable, headache, neck stiffness, vision problems, loss of movement in any part of your body; or
• signs of tumor cell breakdown - confusion, tiredness, numbness or tingling,
muscle cramps, muscle weakness, vomiting, diarrhea, fast or slow heart rate, seizure.”
What are the side effects of chemotherapy drug 5 FU, antimetabolite, which has a 30% rate?
- Diarrhea
- Nausea and possible occasional vomiting
- Mouth sores
- Poor appetite (impacts therapy)
- Watery eyes, sensitivity to light (photophobia)
- Taste changes, metallic taste in mouth during infusion
- Discoloration along vein through which the medication is given
- Low blood counts (anemia risk) (impacts therapy)
What are the potential structural and functional impacts of radiation therapy?
• 40 Gy + results in skin effects - Hair loss can occur with >1Gy - Dryness of glands • 50 Gy + results in bone effects • 60 Gy + results in soft tissue effects • 70 Gy + results in muscle and tendon effects
What is dose of radiation?
The irradiation absorbed by
each kilogram of tissue expressed as Grays (Gy) - 1 Gy = 1 J/kg of tissue.
What determined the total dose of radiation administered to a pt?
Total dose determined by tumor sensitivity and tissue
tolerance
How is radiation therapy usually administered?
The dose is usually given in a number of daily fractions, where they get 1-2 Gy each visit. Typical treatment is 1.5-2 Gy/ visit
In most solid tumors, which is the case in most cancers, how many Gy of radiation does the pt receive?
40-60 Gy, which means they are going to get between 40-60 treatments if they get 1 Gy per visit, or 20-30 treatments if they get 2 Gy per visit.
The goals of PT for a pt with cancer are to prevent, restore, support and to be palliative. What are we trying to prevent in a pt with cancer?
• Before the development of disability
• Lessen severity or shorten
duration
The goals of PT for a pt with cancer are to prevent, restore, support and to be palliative. What are we trying to restore in a pt with cancer?
• Return to former status is expected, without handicap or
residual disease
• Return to gainful occupation
The goals of PT for a pt with cancer are to prevent, restore, support and to be palliative. What are we trying to support in a pt with cancer?
• Ongoing disease is controlled or slowly progressing
• Maintain degree of function
through training and care
The goals of PT for a pt with cancer are to prevent, restore, support and to be palliative. What are we trying to be palliative about in a pt with cancer?
- Increasing disability is expected from relentless disease progression
- Prevent or reduce complications
- Allow them to control their exit
What are the most common cancer related side effects to screen for and how do we screen for them?
• Fatigue (shortness of breath) - Fatigue Severity Scale - Figure 8 Walk Test - Stanford Fatigue Scale • Anemia - Hemoglobin and Hematocrit • Hair loss or integumentary issues - Various symptom inventory tools • Gastrointestinal problems - Various symptom inventory tools • Pain - Visual analog scale - Pain drawings - Numerical pains scales
What needs to be done in order to clear a pt with general cancer for exercise?
• Evaluate for comorbidities
• Exercise testing is not
generally required for walking, flexibility and weight
training
• If exercise testing is needed
for higher level aerobic activity then follow ACSM for testing and contraindications
What needs to be done in order to clear a pt with colon cancer for exercise?
Evaluate ostomy self-care
What needs to be done in order to clear a pt with breast cancer for exercise?
- Evaluate the arm/shoulder
* Lymphedema risk
What needs to be done in order to clear a pt with prostate cancer for exercise?
- Evaluate pelvic girdle
* Lymphedema risk
What needs to be done in order to clear a pt with gyn cancer for exercise?
- Evaluate pelvic girdle
* Lymphedema risk
What needs to be done in order to clear a pt with lung cancer for exercise?
Evaluate pulmonary function
What is the possible PT intervention for a cancer pt that present with SOB?
Aerobic exercise, endurance training in order to be able to tolerate mod level activity
What is the possible PT intervention for a cancer pt that present with LE swelling?
- Edema management
* Reduce lymphedema risk
What is the possible PT intervention for a cancer pt that present with coordination deficits?
- Balance
* Coordination
What is the possible PT intervention for a cancer pt that present with muscle weakness?
Muscle strengthening